Objective: Due to the complex relationship between kisspeptin and hypothalamic-pituitary-gonadal axis, study was planned measure levels in polycystic ovary syndrome (PCOS) analyze correlations PCOS-related reproductive, metabolic changes.Methods: The designed as a prospective Dokuz Eylul University December 2011 September 2013. A total of 285 PCOS cases 162 controls were recruited. After antropometric measeruments physcial examination, blood samples taken for biochemical analysis.Results:...

Objectıve: The aim of the study is to investigate effect myo-inositol (MYO) on pregnancy rates patients diagnosed with polycystic ovary syndrome (PCOS) who undergone controlled ovulation induction and intrauterine insemination (IUI).Methods: A total 196 infertile PCOS admitted Dokuz Eylul University Faculty Medicine were included in between March 2013 May 2016. group 1 (n = 98) given 4 g MYO 400 μg folic acid before during induction. ovarian hyperstimulation (COH) recombinant FSH IUI. 2 98),...

Recently, myoinositol (myo-ins) and folic acid combination has gained an important role for treating Polycystic Ovary Syndrome (PCOS), in addition to combined oral contraceptives (COC). We aimed examine myo-ins effects on anti-Mullerian hormone (AMH) levels compare them with those ones obtained administering COC. In this prospective study, 137 PCOS patients, diagnosed according Rotterdam criteria admitted the Reproductive Endocrinology Infertility Outpatient Clinic at Dokuz Eylul University...

Villitis of unknown etiology (VUE) is noninfectious chronic villitis thought to be associated with fetal growth restriction and stillbirth. COVID-19 the pandemic SARS-CoV-2 infection can cause an increased risk in pregnant women for potential maternal complications from immunological mechanism. We report a 39-week-gestational-age infant delivered 37-year-old mother diagnosed at 37 weeks gestation. The placental examination showed morphological features VUE. immunohistochemically that...

Slow flow HD is a Doppler Ultrasound modality that typically geared toward visualization of small‐size vessels and low velocity blood flow. In this commentary, we emphasize the importance implementing use as an adjunct to traditional modalities in echocardiography screening both first second trimester. This carries many characteristics allow it overcome limitations our current ultrasound facilitate mapping entirety fetal heart. The clinical implications are significant regard earlier...

Objective To analyse the pregnancy outcome by combining plasma homocysteine with uterine artery Doppler velocimetry at 11 to 14 weeks of gestation. Method A prospective cohort study 103 healthy pregnant women. Uterine was performed between and Abnormal blood flow defined as average pulsatility index >1.5 presence unilateral or bilateral diastolic notch. scores were calculated a modified scoring method velocity waveforms. Serum for measurement homocysteine, vitamin B 12 folate levels...

Magnetic resonance imagining (MRI) is gradually becoming the more preferred imaging modality in evaluation of central nervous system (CNS) abnormalities rather than foetal ultrasonography (USG). The aim this study was to compare findings prenatal neurosonography and MRI. a retrospective analysing records 160 pregnant women who underwent both MRI USG due suspicion CNS between 2008 2019. Indications for applying were findings. When compatibility results examined abnormalities, it found fully...

Amaç: İnsan koryonik gonadotropin (hCG), son foliküler olgunlaşmayı ve ovulasyonu tetiklemek için intrauterin inseminasyonda (IUI) kullanılan standart bir tedavidir.Bu çalışmanın amacı, hCG tetikleme uygulamasına salgılatıcı hormon agonisti (GnRHa) eklemenin oosit olgunlaşması üzerine etkisini klinik gebelik sonuçlarını araştırmaktır.Gereç Yöntemler: Bu, üçüncü basamak merkezde gerçekleştirilen retrospektif kesitsel çalışmadır.Kliniğimizde ile kombine IUI tedavisi uygulanan toplam 74 primer...

Amaç: Abortus, ilk trimester gebeliklerinin en sık görülen komplikasyonudur ve gelişen embriyonun sitogenetik anormalliği, bozulmuş implantasyon plasentasyon ile ilişkilidir.Günümüzde abortus riskini doğru bir şekilde öngören güvenilir biyobelirteç bulunmamaktadır.Kisspeptinler, KISS1 geni tarafından kodlanan peptit ailesidir.Kisspeptin, insanlarda gebelik boyunca plasentada yüksek oranda eksprese edilir.Çalışmamızda, yardımcı üreme teknikleri kullanılarak elde edilen 18-40 yaş arası...

Umbilical artery\vein, middle cerebral artery, and ductus venosus Doppler velocimetry were performed at 33 weeks of gestation in the settings an intrauterine growth restricted fetus during a heart rate deceleration. Interestingly, we recorded sudden onset redistribution fetal blood flow with bradycardia. Spontaneous normalization waveforms was observed once returned to normal. Our case provides evidence circulatory variation human resulting from acute incident causing

Introduction: Maternal regulatory T (Treg) cells play a pivotal role in establishing general immune homeostasis the decidua for maintenance of pregnancy. We aimed this study to investigate relationship between mRNA expression immunomodulatory genes and CD25+ Treg with early pregnancy losses. Methods: Our included 3 groups losses including sporadic spontaneous abortions, recurrent abortions post IVF treatment control group. performed RT-PCR analyzing levels 6 CD25 immunohistochemistry...

The coronavirus disease (COVID-19) has created a serious health problem in pregnant people. We aimed to address whether vaccination can prevent development of placental SARS-CoV-2 infected mothers.We reported the pathology findings obtained from routine histopathological examination placentas overall 38 cases.We found low prevalence vaccinated people with active infection comparison those unvaccinated cases.Based on our findings, pathological lesions and may lower risk illness

Background: The pathogenesis of endometriosis is still debatable, and many studies reported a predisposition to infectious immunological factors. In this study, we aimed evaluate the human papillomavirus (HPV) positivity in pain-related symptoms infertility. Methods: cross-sectional 410 patients were enrolled study. HPV-positive (n = 202) HPV-negative 208) compared with symptoms, infertility, endometrioma presence. term “Other HPV” was utilized encompass all HPV types exception 16 18, which...

This paper reports the measures taken to manage impact of COVID-19 pandemic on O&G services in a tertiary referal centre and their outcomes. All patients included this study received inpatient treatment underwent surgery between March 10 2020 end June 2020, including obstetric or gynaecologic cases combined. Data age, diagnosis, operation, duration preoperative postoperative hospital stay, status were recorded. was diagnosed with nasopharyngeal swab test. Thirty-seven (20%) 177 operations...

The aim of this study is to retrospectively examine invasive diagnostic methods, structural anomalies accompanying cystic hygroma, and pregnancy outcomes in hygroma cases admitted a tertiary centre. population the consisted 29 live foetuses with foetal neck only first or second trimester. In study, pregnant women who applied our centre were included. Amniocentesis chorionic villus sampling was performed for genetic analysis according weeks diagnosed by ultrasound examination two clinicians...

Measurement of urinary β2M (beta 2-microglobulin) is a sensitive and reliable assay for detecting tubular injury, renal toxicity, lymphomas, leukemia, or myeloma.Some chemical substrates may increase the level in-vivo.Elevated in urine unusual because it rapidly degrades when pH below 6.The bladder can also be used as marker to assess maturation neonates.β2M could result fetal megacystis, which an abnormally enlarged appearing after 10 weeks gestation, fetus begins produce...

"Abnormal patterns of blood flow through the uterine arteries: Is it a clue for placental abruption in clinically suspected cases?." Journal Obstetrics and Gynaecology, 35(8), pp. 869–870