A5006027471- Memory and Neural Mechanisms
- Primate Behavior and Ecology
- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
- Neuroscience and Neuropharmacology Research
- Neonatal and fetal brain pathology
- Hemispheric Asymmetry in Neuroscience
- Human Pose and Action Recognition
- Face Recognition and Perception
- Multimodal Machine Learning Applications
- Domain Adaptation and Few-Shot Learning
- Evolutionary Psychology and Human Behavior
- Autism Spectrum Disorder Research
- Neural dynamics and brain function
- Advanced MRI Techniques and Applications
- Williams Syndrome Research
- Human-Animal Interaction Studies
- Animal Vocal Communication and Behavior
- RNA modifications and cancer
- Functional Brain Connectivity Studies
- Ureteral procedures and complications
- Urinary and Genital Oncology Studies
- Circular RNAs in diseases
- Olfactory and Sensory Function Studies
- Bladder and Urothelial Cancer Treatments
University of Miami
2023
The Affiliated Yongchuan Hospital of Chongqing Medical University
2023
Chongqing Medical University
2023
University of California, Davis
2008-2022
Oregon National Primate Research Center
2017
The University of Texas Health Science Center at Houston
2002-2009
The University of Texas Health Science Center at San Antonio
2007-2008
Institute of Behavioral Sciences
2001-2006
The role of the amygdala in dyadic social interactions adult rhesus monkeys (Macaca mulatta) was assessed after bilateral ibotenic acid lesions. Social, nonsocial, and spatial behaviors amygdalectomized control were 3 experiments: constrained, unconstrained, round robin. Lesions produced extensive damage to amygdala. Across all experiments, demonstrated increased affiliation, decreased anxiety, confidence compared with monkeys, particularly during early encounters. Normal subjects also...
Social dominance, personality ratings, and frequency, duration, timing of social behaviors were measured pre- postsurgically in 6 groups rhesus monkeys (Macaca mulatta), each consisting 1 sham-operated control monkey with a selective amygdala, hippocampal, or orbital frontal cortex lesion. Unlike previous reports, none the operated showed changes dominance postsurgery, although other measures varied by lesion site. Although displayed heightened avoidant, anxious, aggressive behaviors, those...
The authors measured the effects of bilateral amygdaloid, orbital frontal, or hippocampal lesions on emotional reactivity and passive avoidance in rhesus monkeys (Macaca mulatta). Animals were presented with 8 neutral aversive objects, each paired a highly preferred food reward. Sham-operated control animals displayed heightened defensive behaviors typically would not approach retrieve when potential predator (coiled rubber snake), 2 conditioned stimuli for laboratory-housed (a capture net...
Abstract Malformations of the hippocampal formation and amygdala have been implicated in several neurodevelopmental disorders; yet relatively little is known about their normal structural development. The purpose this study was to characterize early developmental trajectories hippocampus rhesus macaques ( Macaca mulatta ) using noninvasive MRI techniques. T1‐weighted scans 22 infant juvenile monkeys (11 male, 11 female) were obtained between 1 week approximately 2 yrs age. Ten animals (five...
Abstract We examined the effects of bilateral amygdaloid, hippocampal or orbital frontal cortex lesions on reward assessment in rhesus monkeys ( Macaca mulatta ). In Experiment 1, basic preferences for foods and inedible nonfoods were measured pre‐ postsurgery. None produced changes animals' palatable raw meat relative to presurgery, although amygdaloid yielded increased preference When reinforcement value each animal's highest‐preferred food was decreased by selective satiation, only...
Rhesus monkeys (Macaca mulatta) with bilateral ibotenic acid-produced lesions of the amygdala were compared controls in several novel situations, including exposures to metal objects, toy animals, and a person. Early testing, showed reduced inhibitions on responsiveness controls. With continuing exposures, differences between groups diminished sharply as waned This outcome is consistent hypothesis that mediates caution initial reactions ambiguous or threatening which, absence adverse...
Abstract Human and nonhuman primates rely almost exclusively on vision for social communication. Therefore, tracking eye movements examining visual scan paths can provide a wealth of information about many aspects primate processing. Although eye‐tracking techniques have been utilized with humans some time, similar studies in less frequent over recent decades. This has largely owing to the need invasive manipulations, such as surgical implantation devices limit head movement, which may not...
The sophisticated analysis of gestures and vocalizations, including assessment their emotional valence, helps group-living primates efficiently navigate social environment. Deficits in information processing emotion regulation are important components many human psychiatric illnesses, such as autism, schizophrenia anxiety disorder. Analyzing the neurobiology requires a multidisciplinary approach that benefits from comparative studies humans animal models. However, questions remain regarding...
Autonomic nervous system activity is an important component of affective experience. We demonstrate in the rhesus monkey that both sympathetic and parasympathetic branches autonomic respond differentially to valence passively viewed video stimuli. recorded cardiac impedance electrocardiogram while adult macaques watched a series 300 30-second videos varied their content. found (as measured by pre-ejection period) increased respiratory sinus arrhythmia) decreased as content changes from...
Although the amygdala has been repeatedly implicated in normal primate social behavior, great variability exists specific and nonsocial behavioral changes observed nonhuman primates with bilateral lesions. One plausible explanation pertains to differences context. This study measured behavior of amygdala-lesioned unoperated rhesus monkeys (Macaca mulatta) 2 contexts. Monkeys interacted 4-member groups over 32 test days. They were previously assessed pairs (N. J. Emery et al., 2001) therefore...
Abstract Very humanlike artificial agents can induce feelings of uneasiness in human perceivers. Stimuli that generate this response are said to occupy “the uncanny valley”. Given inconsistent findings the literature, whether or not nonhuman animals experience valley is unclear. Here, we recorded visual attention eleven male rhesus monkeys as they viewed faces varying realness across five levels, with measured by both number and duration fixations on a whole areas interest within (e.g.,...
Despite evolutionary claims about the function of facial behaviors across phylogeny, rarely are those hypotheses tested in a comparative context-that is, by evaluating how nonhuman animals process such behaviors. Further, while increasing evidence indicates that humans make meaning faces integrating contextual information, including from body, extent to which information during affective displays is unknown. In present study, we evaluated rhesus macaques (Macaca mulatta) dynamic conspecifics...
Across a variety of species, the amygdala appears to play key role in detection and avoidance potential dangers (e.g., unfamiliar social partners, novel objects or contexts, predators, etc.). For many seeking out appropriate food sources avoiding novel, distasteful potentially tainted is also daily concern. Amygdala damage nonhuman primates has been linked increased willingness select unpalatable foods, as well inedible items that intact animals typically reject. However, such findings have...
The ability to navigate through space involves complex interactions between multiple brain systems. Although it is clear that spatial navigation impaired during aging, the networks responsible for these altered behaviors are not well understood. Here, we used a within-subject design and [ 18 F]FDG-microPET capture whole-brain activation patterns in four distinct from young aged rhesus macaques: constrained (CAGE), head-restrained passive locomotion (CHAIR), (TREADMILL), unconstrained (WALK)....