A5029877929- Advanced biosensing and bioanalysis techniques
- Advanced Nanomaterials in Catalysis
- Biosensors and Analytical Detection
- Nanocluster Synthesis and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Electrochemical sensors and biosensors
- Carbon and Quantum Dots Applications
- RNA Interference and Gene Delivery
- Mercury impact and mitigation studies
- Advanced Biosensing Techniques and Applications
- MicroRNA in disease regulation
- Agriculture, Soil, Plant Science
- DNA and Nucleic Acid Chemistry
- Sulfur Compounds in Biology
- Luminescence and Fluorescent Materials
- Soil Carbon and Nitrogen Dynamics
- SARS-CoV-2 detection and testing
- Porphyrin and Phthalocyanine Chemistry
- COVID-19 Clinical Research Studies
- Bacterial Identification and Susceptibility Testing
- Mycotoxins in Agriculture and Food
- Calcium Carbonate Crystallization and Inhibition
- Pesticide and Herbicide Environmental Studies
- Bacteriophages and microbial interactions
- Enterobacteriaceae and Cronobacter Research
Gannan Normal University
2018-2025
Henan Normal University
2020-2024
Sichuan Agricultural University
2024
Northeast Agricultural University
2023
Hunan University
2020-2021
State Key Laboratory of Chemobiosensing and Chemometrics
2020-2021
Fuzhou University
2013-2019
First Affiliated Hospital of Xiamen University
2019
Northwest University
2019
Ganzhou People's Hospital
2019
Herein, we report for the first time a colorful chromogenic substrate, which displays vivid color responses in presence of different concentration analytes. Our investigation reveals that selective shortening gold nanorods (AuNRs) could generate series distinct colors covers nearly whole visible range from 400 to 760 nm. These can be easily distinguished by naked eye; as result, accuracy visual inspection greatly improved. Next, demonstrate utility AuNRs multicolor substrate develop number...
Abstract In this work, 3,3′,5,5′-tetramethylbenzidine(II) (TMB 2+ ), derived from H 2 O -horseradish peroxidase (HRP)-3,3′,5,5′-tetramethylbenzidine (H -HRP-TMB) reaction system, was used to etch AuNRs generate different colors of solution. Many enzyme reactions are involved in the production (e.g., glucose can react with dissolved oxygen presence oxidase (GOx) produce ). Given information, a simple visual biosensor developed study, as example target. The detection range proposed system...
Here, a fully integrated multicolor immunosensor was developed for sensitive and reliable semiquantitative analysis of HIV-1 p24, which integrates the multistep reactions horseradish peroxidase (HRP)-linked immunoassay gold nanorod (AuNR)-based assay into single microfluidic chip. The HRP-linked functions by moving magnetic beads bound to capture antibody through different aqueous phases containing reagents. HRP-catalyzed oxidation 3,3′,5,5′-tetramethylbenzidine (TMB) is used mediate AuNRs...
On the basis of different diffusivity and existence electrostatic repulsion between long short DNA on negatively changed indium tin oxide (ITO) microelectrode, a simple but sensitive immobilization free solution-phase electrochemical method for methylation detection inhibitor screening has been developed. Electroactive substance (methylene blue) tagged at penultimate base T close to 3′-terminal first, in absence methylation, methylene blue-labeled electroactive fragments cannot be generated...
The electronic balance, one of the most common pieces equipment in laboratory, is normally used to directly measure weight a target with high accuracy. However, little attention has been paid extension its applications. In this study, an balance was as readout develop novel aptasensor for protein quantification first time. Thrombin selected model target, and two aptamers recognizing different sites were (one aptamer immobilized on surface magnetic microparticles other functionalized platinum...
Abstract Colorimetric enzyme-linked immunosorbent assay utilizing 3′-3-5′-5-tetramethylbenzidine(TMB) as the chromogenic substrate has been widely used in hospital for detection of all kinds disease biomarkers. Herein, we demonstrate a strategy to change this single-color display into dual-color responses improve accuracy visual inspection. Our investigation firstly reveals that oxidation state 3′-3-5′-5-tetramethylbenzidine (TMB 2+ ) can quantitatively etch gold nanoparticles. Therefore,...
This approach utilizes the antibody-conjugated silver nanoparticle complex as an alternative to natural enzymes for signal generation, overcoming structural instability and environmental susceptibility inherent enzymes.
In this work, seed-mediated synthesis of gold nanorods (AuNRs) is demonstrated for multicolor biosensing the first time.
Thermometers, one of the most commonly used instruments at home, are normally adapted to measure temperature directly with high accuracy but rarely adopted act as readout in biosensors. It is necessary find some ways establish a relationship between concentration target and change. In this study, common thermometer was develop convenient immunosensor. The designed immunosensor comprises three components, including recognition area, water flow system, exothermic reaction bottle. capture...
Escherichia coli ( E. ) O157:H7 can cause many food safety incidents, which seriously affect human health and economic development. Therefore, the sensitive, accurate, rapid determination of is great significance for preventing outbreak spread foodborne diseases. In this study, a carbon dots-Fe 3 O 4 nanomaterial (CDs-Fe )-based sensitive electrochemical biosensor detection was developed. The CDs have good electrical conductivity, surface dots contains abundant carboxyl groups, be used to...
Developing nanozyme-based free radical scavenging is a promising signal modulation approach for ECL sensing. Nevertheless, the relatively low antioxidant activity and inherent pro-oxidant of numerous nanozymes have significantly hindered development this strategy. Here biofunctional copper-based metal-organic framework (CuMOF) with multiple enzyme-mimicking activities was employed immunosensor, guided by self-cascade reaction. The SOD, CAT, capacity to eliminate ·OH endow CuMOF powerful...
Due to its unique biological composition, aquatic products, especially fish, are extremely perishable compared other muscle products. Herein, we proposed an artificial nanozyme-based colorimetric detection of hypoxanthine (Hx), the indicator fish freshness, in a minute-time scale without assistance natural enzyme (hypoxanthine oxidase). The principle is based on interaction between Hx and polyvinylpyrrolidone-modified platinum cubic nanomaterials (PVP-PtNC), which catalytic active sites...