A5011889763- Gastrointestinal motility and disorders
- Gut microbiota and health
- Advancements in Battery Materials
- Gastroesophageal reflux and treatments
- Esophageal Cancer Research and Treatment
- Advanced Battery Materials and Technologies
- Helicobacter pylori-related gastroenterology studies
- Eosinophilic Esophagitis
- Diet and metabolism studies
- Esophageal and GI Pathology
- Supercapacitor Materials and Fabrication
- Clostridium difficile and Clostridium perfringens research
- Gastric Cancer Management and Outcomes
- Molecular Sensors and Ion Detection
- HIV Research and Treatment
- Dialysis and Renal Disease Management
- Advanced biosensing and bioanalysis techniques
- Genomics and Phylogenetic Studies
- Inflammatory Bowel Disease
- Tryptophan and brain disorders
- HIV/AIDS drug development and treatment
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Berberine and alkaloids research
- Ginseng Biological Effects and Applications
Peking University Third Hospital
2016-2025
Peking University
2016-2025
National Institute for Parasitic Diseases
2011-2025
Shenzhen Polytechnic
2025
University of Science and Technology Liaoning
2025
Vector (United States)
2025
Anhui University of Finance and Economics
2025
China University of Petroleum, East China
2025
China Energy Engineering Corporation (China)
2025
Laboratoire de Chémo-biologie synthétique et thérapeutique
2025
Keeping mammalian gastrointestinal (GI) tract communities in balance is crucial for host health maintenance. However, our understanding of microbial the GI still very limited. In this study, samples taken from tracts C57BL/6 mice were subjected to 16S rRNA gene sequence-based analysis examine characteristic bacterial along mouse tract, including those present stomach, duodenum, jejunum, ileum, cecum, colon and feces. Further analyses 283,234 valid sequences obtained pyrosequencing revealed...
A highly selective and sensitive OFF-ON fluorescent sensor 1, employing the PET mechanism, was designed synthesized. It could be used to detect Cd2+ ion in aqueous solution image living cells. The fluorescence intensity significantly enhanced about 195-fold quantum yield increased almost 100-fold. Moreover of 1 linearly with high sensitivity (0−1 μM) toward Cd2+.
Emerging evidence indicates that psychological stress is involved in the pathogenesis of irritable bowel syndrome, which characterized by visceral hypersensitivity and may be accompanied gut dysbiosis. However, how such contributes to development incompletely understood. Here, we aimed investigate influence stress-induced microbial changes exert on sensitivity, as well possible underlying mechanisms associated with this effect.Male Sprague-Dawley rats underwent chronic water avoidance (WAS)...
Depression is a recurrent, heterogeneous mood disorder occurring in more than 260 million people worldwide. Gut microbiome dysbiosis associated with the development of depressive-like behaviors by modulating neuro-biochemical metabolism through microbiome-gut-brain (MGB) axis. Fecal microbiota transplantation (FMT) has been proposed as potential therapeutic solution for depression, but efficiency and mechanism are unknown. Here, we performed an FMT from Sprague-Dawley (SD) rats ('healthy'...
Layered transition-metal (TM) oxides have drawn ever-growing interest as positive electrode materials in potassium-ion batteries (PIBs). Nevertheless, the practical implementation of these is seriously hampered by their inferior cyclic property and rate performance. Reported here a self-templating strategy to prepare homogeneous P2-K0.6CoO2 (KCO) microcubes. Benefiting from unusual microcube architecture, interface between electrolyte active material considerably diminished. As result, KCO...
Prussian white (PW) is considered as a promising cathode material for potassium-ion batteries (KIBs) due to its low cost and high theoretical capacity. However, the water content structural defects strict synthesis conditions of PW lead unsatisfactory cycling performance specific capacity, hindering practical applications. Herein, template-engaged reduction method proposed, using MIL-88B(Fe) self-template KI reducing agent prepare K-rich with content. Furthermore, hierarchical porous...
Abstract Layered transition metal oxides are extensively considered as appealing cathode candidates for potassium‐ion batteries (PIBs) due to their abundant raw materials and low cost, but further implementations limited by slow dynamics impoverished structural stability. Herein, a layered composite having P2 P3 symbiotic structure is designed synthesized realize PIBs with large energy density long‐term cycling The unique intergrowth of phases in the obtained oxide plainly characterized...
Abstract The interfacial electric field (IEF) in the heterostructure can accelerate electron transport and ion migration, thereby enhancing electrochemical performance of potassium‐ion batteries (PIBs). Nevertheless, quantification modulation IEF for high‐efficiency PIB anodes currently remains a blank slate. Herein, we achieve first time tuning via amorphous carbon‐coated undifferentiated cobalt‐doped FeSe/Fe 3 Se 4 (denoted UN‐CoFe 5 /C) efficient potassium storage. Co doping increase ,...
Background Despite their wide occurrence, cryptosporidiosis and giardiasis are considered neglected diseases by the World Health Organization. The epidemiology of these microsporidiosis in humans developing countries is poorly understood. high concentration pathogens raw sewage makes characterization transmission simple through genotype subtype analysis a small number samples. Methodology/Principal Findings distribution genotypes subtypes Cryptosporidium spp., Giardia duodenalis,...
Background Over 200 cryptosporidiosis outbreaks have been reported, but little is known if other enteric pathogens were also involved in some of these outbreaks. Recently, an outbreak linked to poor hygiene by two Cryptosporidium hominis subtypes occurred a pediatric hospital ward (Ward A) China, lasting for more than 14 months. In this study, the concurrence during three with similar transmission route, Giardia duodenalis, Enterocytozoon bieneusi, and Clostridium difficile, was assessed....
A new fluorescent Pd2+ sensor 1, N-butyl-4-(p-methyloxy)-phenylethynyl-5-thiophenemethylamino-1,8-naphthalimide, was designed and synthesized. It showed highly selective on–off fluorescence changes for among the representative transition heavy metallic cations, its efficiently quenched by 5 equivalents of in buffer solution. The also displayed a chromogenic behavior toward from yellow to black-red, which could be easily observed naked eye.
The esophageal intraluminal baseline impedance may be used to evaluate the status of mucosa integrity. Esophageal acid exposure decreases impedance. We aimed compare in patients with various reflux events and different acid-related parameters, investigate relationships between epithelial histopathologic abnormalities impedance.A total 229 GERD 34 controls underwent 24-h multichannel pH monitoring (MII-pH monitoring), gastroendoscopy, completed a questionnaire (GerdQ). quantified...
Objective Description of the design and preliminary results baseline recruitment screening in endoscopic for esophageal cancer China (ESECC), first randomised controlled trial (RCT) assessing efficacy cost-effectiveness squamous cell carcinoma (ESCC). Design ESECC is a cluster RCT, 668 villages rural Hua County, Henan Province, high-incidence area ESCC China, were into two arms at ratio 1:1. Screening arm participants screened by Lugol chromoendoscopy; no was performed control arm....
The gut microbiota is recognized as a promising therapeutic target for anxiety. Berberine (BBR) has shown efficacy in the treatment of diseases such postmenopausal osteoporosis, obesity, and type 2 diabetes through regulating microbiota. However, effects BBR on anxiety are still unclear. purpose study to test whether ameliorates by modulating intestinal under estrogen-deficient conditions. Experimental was established specific pathogen-free (SPF) ovariectomized (OVX) rats, which were then...
Potassium manganese hexacyanoferrate shows great potential as a cathode material for potassium-ion batteries (PIBs) due to its impressive electrochemical performance, abundant elements, and easy synthesis. However, severe capacity fading poor K+ diffusion kinetics greatly limit large-scale application. Herein, we propose facile anion exchange method construct Mn–Ni Prussian blue analogue (denoted MnNi-PBA) spheres. The introduction of Ni can stabilize the structure enhance cycling rich...
The gut microbiota plays a prominent role in gut-brain interactions and dysbiosis is involved neuroinflammation. However, specific probiotics targeting neuroinflammation need to be explored. In this study, the antineuroinflammatory effect of potential probiotic Roseburia hominis (R. hominis) its underlying mechanisms investigated.First, germ-free (GF) rats are orally treated with R. hominis. Microglial activation, proinflammatory cytokines, levels short-chain fatty acids, depressive...