A5100342671- MicroRNA in disease regulation
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Hepatitis B Virus Studies
- Surgical Sutures and Adhesives
- Wound Healing and Treatments
- Hepatitis C virus research
- Hepatocellular Carcinoma Treatment and Prognosis
- Bone Metabolism and Diseases
- Developmental Biology and Gene Regulation
- RNA Interference and Gene Delivery
- Hydrogels: synthesis, properties, applications
Northwest University
2025
Eastern Hepatobiliary Surgery Hospital
2014-2024
Second Military Medical University
2014-2024
The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture
2021
Chongqing Three Gorges Central Hospital
2017
Second Affiliated Hospital of Xi'an Jiaotong University
2017
Let-7 family microRNAs have been reported to be downregulated in human hepatocellular carcinoma comparison with normal hepatic tissues. Among them, let-7g was identified as the lowest expression using real-time RT-PCR. However, mechanism by which works remains unknown. Here, our present study, we had reexpressed vitro cell lines MHCC97-H and HCCLM3 via transfection. The proliferation after reexpression of assayed MTT method; migration invasion restoration were detected wound-healing...
MicroRNAs (miRs) are small noncoding RNA molecules and recently have demonstrated that altered expression functions their tight association with ulcerative colitis (UC). Previous microarray study reported miR-214 was downregulated in the sigmoid colon of patients active UC, but roles pathogenesis UC remain to be elucidated. In this study, significant lower level miR-214-3p higher STAT6 intestinal mucosa compared health controls were confirmed by quantitative real-time PCR. Results luciferase...
Abstract Serum hepatitis B core‐related antigen (HBcrAg) is considered a surrogate marker of the amount and activity intrahepatic covalently closed circular DNA. This study aimed to explore prognostic value HBcrAg on patients with virus (HBV)‐related hepatocellular carcinoma (HCC) after curative hepatectomy undergoing antiviral therapy (AVT). Data 949 consecutive HBV‐related HCC resection between 2010 2013 were reviewed. levels measured at surgery (baseline) for all time 2 years...
NF- κ B activation and its abnormal expression are involved in the progression of glioma. miRNA plays a crucial role bone diseases. The is becoming more important. purpose this study to explore mechanism by how miR-1 regulates signaling. C57 glioma mouse models were divided into osteoporosis (OP) group control group. qPCR was used measure levels OP mice. Bone marrow mesenchymal stem cells (BMSCs) cultured transfected with specific siRNA establish knockout cell model followed analysis...