- Cardiac electrophysiology and arrhythmias
- Hepatitis C virus research
- Atrial Fibrillation Management and Outcomes
- Hepatitis B Virus Studies
- Cardiac Arrhythmias and Treatments
- Smart Parking Systems Research
- Liver Disease Diagnosis and Treatment
- Cancer Cells and Metastasis
- Ubiquitin and proteasome pathways
- Evaluation Methods in Various Fields
- Cardiovascular Effects of Exercise
- Cardiomyopathy and Myosin Studies
- COVID-19 and healthcare impacts
- Gastric Cancer Management and Outcomes
- Cardiac Ischemia and Reperfusion
- Microbial infections and disease research
- Mitochondrial Function and Pathology
- Advanced Fiber Optic Sensors
- Wnt/β-catenin signaling in development and cancer
- Tendon Structure and Treatment
- COVID-19 and Mental Health
- Hepatocellular Carcinoma Treatment and Prognosis
- RNA and protein synthesis mechanisms
- Cancer Genomics and Diagnostics
- Ferroptosis and cancer prognosis
Tongji University
2008-2025
Second Military Medical University
2014-2024
Shanghai Tenth People's Hospital
2014-2024
Eastern Hepatobiliary Surgery Hospital
2014-2024
Tongji Hospital
2008-2023
Shanghai East Hospital
2018
Pudong New Area People's Hospital
2014
Anhui Normal University
2012
Ministry of Education of the People's Republic of China
2010
Background Asialoglycoprotein receptor (ASGPR)-ligand-based separation combined with identification Hep Par 1 or pan-cytokeratin (P-CK) antibody have been demonstrated to detect circulating tumor cells (CTCs) in hepatocellular carcinoma (HCC). The aim of this study was develop an improved enrichment and system that allows the detection all types HCC CTCs. Methods specificity prepared anti-ASGPR monoclonal characterized. were bound by ASGPR subsequently magnetically isolated second...
Microtubule integrity is important in cardio-protection, and microtubule disruption has been implicated the response to ischemia cardiac myocytes. However, effects of Taxol, a common stabilizer, are still unknown ischemic ventricular arrhythmias. The arrhythmia model was established isolated rat hearts by regional ischemia, myocardial infarction ischemia/reperfusion. structure immunohistochemically measured. potential mechanisms were studied measuring reactive oxygen species (ROS),...
<title>Abstract</title> Background Data on the impact of antiviral therapy(AVT) long-term outcomes hepatitis B virus(HBV)-related hepatocellular carcinoma(HCC) patients with cirrhosis after hepatectomy are limited. We aimed to determine effect AVT HBV-related cirrhotic HCC. Methods A total 1396 HCC who underwent curative resection and received entecavir for postoperative were categorized into no-AVT groups. Recurrence overall survival(OS) rates compared, especially according initiation time...
Abstract Serum hepatitis B core‐related antigen (HBcrAg) is considered a surrogate marker of the amount and activity intrahepatic covalently closed circular DNA. This study aimed to explore prognostic value HBcrAg on patients with virus (HBV)‐related hepatocellular carcinoma (HCC) after curative hepatectomy undergoing antiviral therapy (AVT). Data 949 consecutive HBV‐related HCC resection between 2010 2013 were reviewed. levels measured at surgery (baseline) for all time 2 years...
Contact method is an important to measure the complex permittivity of polymer films. There are some possible factors affecting its accurate measurement for thin films by direct contact method. To solve problem, this paper analyzes reasons errors induced flatness tolerance and edge effect from view three-electrode structure, that state film surface as well. An equivalent electric circuit model proposed based on surfaces. The correction formulas used with coarse derived according model, then...
Abstract This study aims to analyse the pathological features of skeletal muscle injury repair by using rats model responses different exercise intensities. Eighty‐four were randomly divided into five groups for treadmill exercise. The short‐term control, low‐intensity, medium‐intensity and high‐intensity underwent gastrocnemius sampling after 6, 8 12 weeks long‐term group optical coherence tomography angiography 18 RNA sequencing was performed on samples, followed corresponding histological...
The cardiomyocytes in the superior vena cava (SVC) myocardial sleeve have distinct action potentials and ionic current profiles, but refractoriness of these cells has not been reported. Using standard intracellular microelectrode techniques, we demonstrated sheep that effective refractory period (ERP) SVC (114.7 +/- 6.5 ms) is shorter than inferior (IVC) (166.7 6.2 ms), right atrial free wall (RAFW) (201.0 6.0 appendage (RAA) (203.1 5.8 (P < 0.05). cardiomyocyte ERP was heterogeneously...
Background: The outbreak of novel coronavirus disease 2019 (COVID-19) has led to increasing international concern. Effective screening strategy and early recognition the are crucial limiting spread this worldwide challenge.Methods: Fever clinics 25 hospitals evenly distributed in 16 Districts Shanghai were selected. All patients visiting fever from begin (17 January 2020) February enrolled. A standardized procedure for COVID-19 was presented all suspected cases monitored analyzed till they...
Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive malignancy with poor prognosis. Aspartate β-hydroxylase (ASPH) an α-ketoglutarate-dependent dioxygenase involved in the post-translational hydroxylation of target proteins. ASPH has been demonstrated to be upregulated ICC, yet its role remains elucidated. This study aimed investigate potential function ICC metastasis.Survival curves for overall survival pan-cancer data from The Cancer Genome Atlas (TCGA) database was depicted using...