A5101904794- Thermal Analysis in Power Transmission
- MicroRNA in disease regulation
- Cardiac electrophysiology and arrhythmias
- Cardiac Ischemia and Reperfusion
- Molecular Biology Techniques and Applications
- Lightning and Electromagnetic Phenomena
- Recycling and utilization of industrial and municipal waste in materials production
- Cancer, Lipids, and Metabolism
- Cardiac Fibrosis and Remodeling
- Single-cell and spatial transcriptomics
- Lipoproteins and Cardiovascular Health
- Atherosclerosis and Cardiovascular Diseases
- Power Systems Fault Detection
- Inflammasome and immune disorders
- Cardiac Health and Mental Health
- Multiple and Secondary Primary Cancers
- Coronary Artery Anomalies
- Electrical Fault Detection and Protection
- Heme Oxygenase-1 and Carbon Monoxide
- Cancer-related molecular mechanisms research
- Coronary Interventions and Diagnostics
- Evaluation Methods in Various Fields
- Cardiac Arrest and Resuscitation
- Curcumin's Biomedical Applications
- Cholangiocarcinoma and Gallbladder Cancer Studies
Shanghai Zhabei District Shibei Hospital
2019-2024
Weichai Power (China)
2010-2022
The University of Texas MD Anderson Cancer Center
2021
Nanjing Medical University
2012-2016
Wuxi People's Hospital
2012-2016
Wuhan Institute of Technology
2014
Tongji University
2010
Background/Aims: Cardiac fibrosis after myocardial infarction (MI) has been identified as a key factor in the development of heart failure, but mechanisms undelying cardiac remained unknown. microRNAs (miRNAs) are novel leading to fibrotic diseases, including fibrosis. Previous studies revealed that miR-22 might be potential target. However, roles and ill defined. The present study thus addressed impact Methods: After seven days following coronary artery occlusion mice, tissues used for...
Endothelial cells (EC) are sensitive to changes in the microenvironment, including hypoxia and ischemia. Disruption of microtubular network has been reported cases However, signaling pathways involved hypoxia-induced disruption unknown. The purpose this study was investigate molecular mechanisms disassembly human umbilical vein endothelial (HUVECs). HUVECs were cultured under normoxic or hypoxic conditions pretreated with without colchicine paclitaxel. MTT assay, Transwell trans-endothelial...
Cardiovascular diseases, including myocardial infarction, remain a leading cause of death globally. Emerging evidence suggests the gut microbiota plays crucial role in cardiovascular health. This study aims to explore impact on infarction using mouse model.
Ischemia/hypoxia and reperfusion impair mitochondria produce a large amount of reactive oxygen species (ROS), which lead to mitochondrial brain damage. Furthermore, heme oxygenase-1 (HO-1) as cytoprotective gene protects cells against ROS-induced cell death in ischemia-reperfusion injury. Induction HO-1 is involved effects taxol.We hypothesize that taxol cardiac myocytes possibly by preserving myocardial function inducing expression through the JNK pathway.In this project, perfused...
HMG-CoA reductase inhibitors (statins) inhibit cholesterol biosynthesis, and also decrease the formation of isoprenoid intermediates required for activation Rho kinase (ROCK) pathway. ROCK pathway plays pivotal roles in cardiovascular diseases including arteriosclerosis. It has been implicated that inhibition can reverse vascular dysfunction humans with atherosclerosis. However, it is not clear whether statins, at doses used to lower levels, activity atherosclerosis.We treated 40 subjects...
Abstract The aim of this study was to investigate the protective effect curcumin (Cu) on myocardial injury in diabetic cardiomyopathy vivo and vitro. Serum glucose, inflammatory cytokines, cardiac function indexes type 2 diabetes db/db mice were measured. mechanism action confirmed by immunohistochemistry, immunofluorescence, western blot experiments. H9C2 cells stimulated glucose (Glu) used as cell models Cu treatment improved tolerance lipid profile reduced production cytokines. In...
Microtubule integrity is important in cardio-protection, and microtubule disruption has been implicated the response to ischemia cardiac myocytes. However, effects of Taxol, a common stabilizer, are still unknown ischemic ventricular arrhythmias. The arrhythmia model was established isolated rat hearts by regional ischemia, myocardial infarction ischemia/reperfusion. structure immunohistochemically measured. potential mechanisms were studied measuring reactive oxygen species (ROS),...
Studies have shown that a C1019T polymorphism of the gene encoding gap junction protein connexin37 is associated with coronary artery disease (CAD). The aim present study was to explore association between in and CAD patients in-stent restenosis (ISR). A total 532 who had undergone stenting angiography at least three months after procedure were divided according clinical diagnosis standard into two groups which ISR (n=67) no (NISR; n=465) groups. further 501 healthy individuals controls....
Normal heart development is vital for maintaining its function, and the process involved in complex interactions between different cell lineages. How mammalian hearts develop differently still not fully understood. In this study, we identified several major types of cardiac cells, including cardiomyocytes (CMs), fibroblasts (FBs), endothelial cells (ECs), ECs/FBs, epicardial (EPs), immune (macrophage/monocyte cluster, MACs/MONOs), based on single-cell transcriptome data from embryonic both...
Islanding detection is an important issue for distributed generation operating with main network. To solve the problem of reliability and sensitivity conventional vector shift method, this paper presents a composite islanding method utilizing both angle change frequency variation derived from generator terminal voltage. The consists criterion auxiliary criterion, each one having its own setting calculating algorithm. establishment working principle proposed are described in detail....
In this paper, according to the 'Technical rule for connecting wind farm power system' promulgated by state, least squares support vector machine (LSSVM) algorithm is used build a mathematical model, and six indicators, namely, voltage deviation, fluctuation, flicker, grid harmonics, frequency deviation three-phase imbalance, are comprehensively considered certain quality level calculated, which evaluate of stations substation access points. LSSVM classification method based on principle...
This paper discusses electric field under overhead lines with a nearby building. Surface charge method is used. Planer triangle surface element chosen. Electric potential and strength produced by planer are presented. And analytical expression deduced. Then of 220kV double circuit building calculated. Results show that above the increases its distortion effect decreases due to shielding effect.
Phosphorus slag is a kind of industrial waste, which not only occupies the land but also causes potential harm to environment. In this paper, insulation board was prepared with phosphorus as main material. It concluded that best when ratio water material 0.3, for 50 wt%, quicklime/zeolite 0.52, cement 10 glass fiber 3 Na2SO4 0.5%, vesicant 0.8% and autoclave curing system 174.5°C 8 hours. And it has an apparent density 0.42 g/cm³, flexural strength 0.54 MPa thermal conductivity 0.068 W/(mK).
Abstract In order to measure the induced voltage of suspended conductor under high-voltage transmission line, a portable floating potential measuring device is developed in this paper. This paper proposes design scheme and develops high-precision sensing detection module ensure its sensitivity accuracy. improve anti-interference performance, isolation protection circuit designed performance system strong electromagnetic environment. Finally, coupling data acquisition multi-physical sensors...