Guanglei Li

ORCID: 0000-0002-0979-288X
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About
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Research Areas
  • Microgrid Control and Optimization
  • Power Systems and Renewable Energy
  • High-Voltage Power Transmission Systems
  • HVDC Systems and Fault Protection
  • Smart Grid Energy Management
  • Geophysics and Sensor Technology
  • Optimal Power Flow Distribution
  • Energy Load and Power Forecasting
  • Seismic Waves and Analysis
  • Power Systems and Technologies
  • Wind Turbine Control Systems
  • Hybrid Renewable Energy Systems
  • Power System Reliability and Maintenance
  • Electric and Hybrid Vehicle Technologies
  • Integrated Energy Systems Optimization
  • Industrial Technology and Control Systems
  • Electric Vehicles and Infrastructure
  • Advanced Chemical Sensor Technologies
  • Mechanical and Optical Resonators
  • Soil erosion and sediment transport
  • Islanding Detection in Power Systems
  • Electric Power System Optimization
  • Evaluation and Optimization Models
  • Cancer-related molecular mechanisms research
  • Smart Grid and Power Systems

Guilin University of Electronic Technology
2025

ShanghaiTech University
2023-2024

Shandong University
2023-2024

Peking University
2024

Shenyang Jianzhu University
2024

Nanjing University of Science and Technology
2024

Harbin Medical University
2023

Second Affiliated Hospital of Harbin Medical University
2023

Xi'an University of Technology
2020-2022

Nanjing Institute of Industry Technology
2020-2022

Claudins, the integral tight junction (TJ) proteins that regulate paracellular permeability and cell polarity, are frequently dysregulated in cancer; however, their role neoplastic progression is unclear. Here, we demonstrated knockout of Cldn18, a claudin family member highly expressed lung alveolar epithelium, leads to enlargement, parenchymal expansion, increased abundance proliferation known distal progenitors, epithelial type II (AT2) cells, activation Yes-associated protein (YAP),...

10.1172/jci90429 article EN Journal of Clinical Investigation 2018-02-04

Importance Trials have not demonstrated superiority of alteplase or tenecteplase vs standard care in patients with mild stroke and raised safety concerns. Prourokinase is an alternative fibrinolytic that may a favorable profile, the benefit-risk profile prourokinase unknown. Objective To investigate efficacy ischemic within 4.5 hours symptom onset. Design, Setting, Participants This was multicenter, prospective, open-label, blinded–end point randomized clinical trial conducted from November...

10.1001/jamaneurol.2024.4688 article EN JAMA Neurology 2025-01-21

Abstract Base editors (BEs) are a recent generation of genome editing tools that couple cytidine or adenosine deaminase activity to catalytically impaired Cas9 moiety (nCas9) enable specific base conversions at the targeted genomic loci. Given their strong application potential, BEs under active developments toward greater levels efficiency and safety. Here, previously overlooked nCas9‐centric strategy is explored for enhancement BE. Based on cytosine BE (CBE), 20 point mutations associated...

10.1002/advs.202405426 article EN cc-by Advanced Science 2024-06-17

As a special microbial fermented tea, the aging year of Liubao tea is crucial determinant its value. This study established fast and high-precision method for identifying age by combining terahertz time-domain spectroscopy technology with chemometric methods. Most common optimization algorithms rely too much on guidance elite individuals in process are prone to fall into local optimal solutions. Therefore, this paper uses differentiated creative search algorithm global thinking optimize...

10.1080/00387010.2025.2450055 article EN Spectroscopy Letters 2025-01-10

Abstract The balance among different CD4 + T cell subsets is crucial for repairing the injured spinal cord. Dendritic (DC)‐derived small extracellular vesicles (DsEVs) effectively activate T‐cell immunity. Altered peptide ligands (APLs), derived from myelin basic protein (MBP), have been shown to affect and reduce neuroinflammation levels. However, application of APLs challenging because their poor stability associated side effects. Herein, it demonstrate that DsEVs can act as carriers APL...

10.1002/advs.202304648 article EN cc-by Advanced Science 2023-11-30

In order to solve the problems of low accuracy and efficiency point cloud registration for stereo camera systems, we propose a binocular method based on IWOA Improved ICP. We following approaches in this paper—the process is divided into two steps complete initial coarse exact registration. stage, an improved Whale Optimization Algorithm (IWOA) nonlinear convergence factor adaptive weight coefficients was proposed realize combination with RANSAC algorithm, obtained transformation matrix used...

10.3390/app12199461 article EN cc-by Applied Sciences 2022-09-21

Increasing environmental issues and energy crises led to rapid developments of hybrid electric vehicles, especially the planetary powertrain system (PHPS). This paper presents a comprehensive review PHPS, focusing primarily on contributions in aspect configuration, classification comparison. In this work, new method for PHPS architectures is proposed according number motors (EMs). addition, two kinds framework, are extensively emphasized terms its architectures, advantages disadvantages....

10.3390/en13020329 article EN cc-by Energies 2020-01-09

In response to the urgent need address climate change and reduce carbon emissions, there has been a growing interest in innovative approaches that integrate AI CDR technology. This article provides comprehensive review of current state research this field aims highlight its potential implications with clear focus on integration CDR. Specifically, paper outlines four main for integrating CDR: accurate emissions assessment, optimized energy system configuration, real-time monitoring scheduling...

10.3390/pr12020402 article EN Processes 2024-02-17

Electrochemical seismic sensors are key components in monitoring ground vibration, which featured with high performances the low-frequency domain. However, conventional electrochemical suffer from low repeatability due to limitations fabrication and limited bandwidth. This paper presents a micro-fabricated sensor force-balanced negative feedback system, mainly composed of sensing unit including porous micro electrodes immersed an electrolyte solution circuit magnet. In this study, devices...

10.3390/s17092103 article EN cc-by Sensors 2017-09-13

Folate deficiency (FD) during pregnancy can cause fetal intrauterine growth restriction in pigs, of which the skeletal dysplasia is a major manifestation. Factors influencing muscle development are very important formation porcine meat quality trait. However, effect folate on and its molecular mechanisms unknown. The objective this study to determine maternal transcriptome piglets from reciprocal cross, full-sibling Landrace (LR) Chinese local breed Laiwu (LW) pigs were used for cross...

10.1371/journal.pone.0082616 article EN cc-by PLoS ONE 2013-12-09

A novel control strategy for battery energy storage system (BESS) which is integrated within photovoltaic power station presented in this paper. Normally the function of BESS to mitigate fluctuation PV meet requirements dispatch center. In paper, besides smoothing, peak shaving also considered BESS, means part capacity idle when fluctuations small and not all needed, then on basis time-in-use electricity price, can take earn extra benefits. Thus, size-limited be fully utilized meanwhile...

10.1109/cac.2017.8243243 article EN 2017-10-01

This paper presents an electrochemical seismic sensor in which paraylene was used as a substrate and insulating layer of micro-fabricated electrodes, enabling the detection signals with enhanced sensitivities comparison to silicon-based counterparts. Based on microfabrication, paralene-based sensors were fabricated thickness spacer 6.7 μm. Compared counterparts ~100 μm layers, parylene-based devices produced higher 490.3 ± 6.1 V/(m/s) vs. 192.2 1.9 at 0.1 Hz, 4764.4 18 318.9 6.5 1 4128.1...

10.3390/s18041165 article EN cc-by Sensors 2018-04-11

This paper reports a MEMS based electrochemical seismometer featured with low cost and wide working bandwidth. In this study, new sensing unit was proposed, in which pair of ultra-thin electrodes large reactive surface areas were integrated on corresponding silicon substrates, leading to 1) an decrease increase yield due the simplified fabrication processes (e.g., only three standard microfabrication steps); 2) bandwidth (0.14Hz -26.81Hz) optimized geometrical parameters, compared...

10.1016/j.proeng.2016.11.277 article EN Procedia Engineering 2016-01-01

In order to assess the greatest impact of electrified railway on power quality points common coupling, a prediction and evaluation method considering is proposed. This paper explains based typical case an system. First, according characteristics traction supply system, all different working conditions load, various indicators at public connection point are simulated calculated. Then, combined with background harmonic test results substations, that take into account obtained. Finally,...

10.1109/acpee51499.2021.9436913 article EN 2022 7th Asia Conference on Power and Electrical Engineering (ACPEE) 2021-04-01

A monolithic electrochemical micro seismic sensor capable of monitoring three-axial vibrations was proposed in this paper. The mainly consisted four sensing units interconnected within flow channels and by interpreting the voltage outputs units, with arbitrary directions can be quantified. sensors are fabricated based on MEMS technologies characterized, which produced sensitivities along x, y, z axes as 2473.2 ± 184.5 V/(m/s), 2261.7 119.6 3480.7 417.2 V/(m/s) at 30 Hz. In addition, x-y,...

10.3390/s18041047 article EN cc-by Sensors 2018-03-31
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