A5080903092- Intimate Partner and Family Violence
- Genomics and Phylogenetic Studies
- Climate Change and Health Impacts
- Global Public Health Policies and Epidemiology
- Neural and Behavioral Psychology Studies
- Child Abuse and Trauma
- Bacteriophages and microbial interactions
- Health disparities and outcomes
- Bacterial Genetics and Biotechnology
- Sex and Gender in Healthcare
- Heart Rate Variability and Autonomic Control
- COVID-19 and healthcare impacts
- COVID-19 Impact on Reproduction
- Healthcare Policy and Management
- South Asian Studies and Conflicts
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Systems, Economic Evaluations, Quality of Life
- Nutritional Studies and Diet
- Migration, Health and Trauma
- Global Health Care Issues
- Nutrition and Health in Aging
- Neurotransmitter Receptor Influence on Behavior
- Machine Learning in Bioinformatics
- Functional Brain Connectivity Studies
- Vaccine Coverage and Hesitancy
Institute for Health Metrics and Evaluation
2022-2024
University of Washington
2022-2024
University of North Carolina at Chapel Hill
2019-2023
Simon Fraser University
2016-2018
Automated prediction of bacterial protein subcellular localization is an important tool for genome annotation and drug discovery. PSORT has been one the most widely used computational methods such analysis; however, it not updated since was introduced in 1991. In addition, neither nor any other available make predictions all five sites characteristic Gram-negative bacteria. Here we present PSORT-B, version bacteria, which as a web-based application at http://www.psort.org. PSORT-B examines...
BackgroundSex and gender shape health. There is a growing body of evidence focused on comprehensively systematically examining the magnitude, persistence, nature differences in health between females males. Here, we aimed to quantify leading causes disease burden males across ages geographies.MethodsWe used Global Burden Disease Study 2021 compare disability-adjusted life-year (DALY) rates for 20 individuals older than 10 years at global level seven world regions, 1990 2021. We present...
Abstract The health impacts of intimate partner violence against women and childhood sexual abuse are not fully understood. Here we conducted a systematic review by comprehensively searching seven electronic databases for literature on violence-associated abuse-associated effects. Following the burden proof methodology, evaluated evidence strength linking and/or to outcomes supported at least three studies. Results indicated moderate association with major depressive disorder maternal...
Understanding the RNA processing of an organism's transcriptome is essential but challenging step in understanding its biology. Here we investigate with unprecedented detail Pseudomonas aeruginosa PAO1, a medically important and innately multi-drug resistant bacterium. We systematically mapped cleavage dephosphorylation sites that result 5′-monophosphate terminated (pRNA) using monophosphate RNA-Seq (pRNA-Seq). Transcriptional start (TSS) were also differential (dRNA-Seq) both datasets...
Life expectancy (LE) differences within and between states by race/ethnicity have not been examined.To estimate LE for selected groups in from 1990 to 2019.Cross-sectional time-series analysis.United States.Deidentified death records Census data were used construct regression models with smoothed time series of mortality 2019.LE at birth, sex year, subgroups people reporting Hispanic, non-Hispanic Black, or White race/ethnicity.Disparities across 8.0 years females 12.2 males 7.9 7.8 2019....
Background Naltrexone, an opioid receptor antagonist that is Food and Drug Administration approved for treating alcohol use disorder ( AUD ), reduces craving intake. Despite known pharmacological properties, little regarding the effects of naltrexone on neural circuit function. Thus, a data‐driven examination in human subjects may offer novel insight into its treatment mechanisms. Methods Twenty‐one using males (22 to 39) participated double‐blind, placebo‐controlled crossover study brain...
The non-selective opioid receptor antagonist, naltrexone is one of the most prescribed medications for treating alcohol and addiction. Despite decades clinical use, mechanism(s) by which reduces addictive behavior remains unclear. Pharmaco-fMRI studies to date have largely focused on naltrexone's impact brain behavioral responses drug or cues decision-making circuitry. We hypothesized that effects reward-associated regions would associate with reduced attentional bias (AB) non-drug,...
Abstract Vaccine hesitancy is an increasing global health threat but much of the recent research has centred on USA. European countries provide interesting context due to increases in vaccine-preventable disease outbreaks as well variability vaccination laws. We investigated spatiotemporal clustering Measles, Mumps, and Rubella coverage Germany, a country with historic absence compulsory also examined measles incidence results. While we did not identify strong spatial patterns geographic our...
ABSTRACT Background Understanding the RNA processing of an organism's transcriptome is essential but challenging step in understanding its biology. Here we investigate with unprecedented detail Pseudomonas aeruginosa PAO1, a medically important and innately multi-drug resistant bacterium. We systematically mapped cleavage dephosphorylation sites that result 5'-monophosphate terminated using new high-throughput methodology called monophosphate RNA-Seq (pRNA-Seq). Transcriptional start (TSS)...
Population Medicine considers the following types of articles:• Research Papers -reports data from original research or secondary dataset analyses.• Review -comprehensive, authoritative, reviews within journal's scope.These include both systematic and narrative reviews.• Short Reports -brief reports research.• Policy Case Studies articles on policy development at a regional national level.• Study Protocols -articles describing protocol study.• Methodology -papers that present different...