A5091494393- Neurological disorders and treatments
- Transcranial Magnetic Stimulation Studies
- Parkinson's Disease Mechanisms and Treatments
- Genetic Neurodegenerative Diseases
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Neuroscience and Neural Engineering
- Muscle activation and electromyography studies
- Intensive Care Unit Cognitive Disorders
- Autoimmune Neurological Disorders and Treatments
- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
- Stroke Rehabilitation and Recovery
- Diet and metabolism studies
- Infectious Encephalopathies and Encephalitis
- Vagus Nerve Stimulation Research
- Genetics and Neurodevelopmental Disorders
- Neurological diseases and metabolism
- Cellular transport and secretion
- Psychosomatic Disorders and Their Treatments
- Prion Diseases and Protein Misfolding
- Nerve Injury and Rehabilitation
- Photoreceptor and optogenetics research
- Gastrointestinal motility and disorders
- Acute Ischemic Stroke Management
Universidade de São Paulo
2020-2025
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2017-2021
Duke University
2013
ABSTRACT Background: More than one-third of COVID-19 patients present neurological symptoms ranging from anosmia to stroke and encephalopathy. Furthermore, pre-existing conditions may require special treatment be associated with worse outcomes. Notwithstanding, the role neurologists in is probably underrecognized. Objective: The aim this study was report reasons for requesting consultations by internists intensivists a COVID-19-dedicated hospital. Methods: This retrospective carried out at...
Epidural electrical spinal cord stimulation has been studied for more than a decade Parkinson's disease symptoms, but compelling evidence its effectiveness is still lacking. The aim of this study was to evaluate the in disease. Participants had diagnosis, gait impairment and freezing gait, no pain. Paddle electrodes were implanted at T2-T4 level. After 6 months parameter selection, subthreshold sham compared through double-blinded randomized evaluation further with suprathreshold...
Abstract Background Gait disorders in patients with Parkinson's disease (PD) can become disabling progression without effective treatment. Objectives To investigate the efficacy of intermittent θ burst trans‐spinal magnetic stimulation (TsMS) PD gait and balance disorders. Methods This was a randomized, parallel, double‐blind, controlled trial. Active or sham TsMS applied at third thoracic vertebra 100% motor threshold, during 5 consecutive days. Participants were evaluated baseline,...
To describe the clinical, neurological, neuroimaging, and cerebrospinal fluid (CSF) findings associated with encephalopathy in patients admitted to a COVID-19 tertiary reference center. We retrospectively reviewed records of consecutive evaluated by consulting neurology team from March 30, 2020 through May 15, 2020. Fifty-five confirmed SARS-CoV-2 were included, 43 whom showed encephalopathy, further divided into mild, moderate, severe groups. Nineteen (44%) had undergone mechanical...
•Chronic spinal cord stimulation effectiveness was evaluated in four PD patients.•Double blinded cross over evaluation performed using subthreshold stimulation.•An open label with regular suprathreshold also performed.•No statistically significant effect produced either stimulation.•This study highlights the lack of strong clinical evidence supporting SCS for PD.
A 30-year-old woman had 5 days of visual hallucinations, nystagmus, memory impairment and mutism. On examination, she was disorientated with reduced attention span, gaze-evoked paratonia abnormal frontal reflexes. Cerebrospinal fluid (CSF) showed 80 cells, protein 0.41 g/L glucose 3.2 mmol/L (plasma 5.0 mmol/L). MR scan the brain involvement limbic extra-limbic regions brainstem. Commercial cell-based assays were negative, but tissue-based neuropil staining, for anti-metabotropic glutamate...
Abstract Objective To describe the clinical, neurological, neuroimaging and cerebrospinal fluid (CSF) findings associated with encephalopathy in patients admitted to a COVID-19 tertiary reference center. Methods We retrospectively reviewed records of consecutive evaluated by consulting neurology team from March 30, 2020 through May 15, 2020. Results Fifty-five confirmed SARS-CoV-2 were included, 43 whom showed encephalopathy, further divided into mild, moderate severe groups. Nineteen (44%)...
<title>Abstract</title> Parkinson’s disease (PD) is a neurological disorder that affects the central nervous system, resulting in progressive impairment of movements, such as tremors, slow muscle stiffness, imbalance, speech and writing disturbances, deterioration gait. Understanding challenges associated with PD, including episodes freezing, where individuals suddenly stop struggle to resume rhythmic has been subject study literature. The reliable detection freezing before it occurs still...
Background: Gait and balance symptoms affect meaningly Parkinson's disease patients, in their quality of life ability. In those who are not responsive to dopaminergic therapy, managing these becomes a treatment challenge. The spinal cord has emerged as promising target for treating gait disturbances patients. Our objective was test whether repetitive Transcranial Magnetic Stimulation over is an effective tool on drug refractory Methods: This open label, prospective, unicentric pilot study....