А. Е. Комлев

ORCID: 0000-0001-6908-7472
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About
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Research Areas
  • Cardiac Valve Diseases and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Aortic Disease and Treatment Approaches
  • Aortic aneurysm repair treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Structural Anomalies and Repair
  • Cardiac Imaging and Diagnostics
  • Cardiac Arrhythmias and Treatments
  • Cardiac pacing and defibrillation studies
  • Cardiovascular Function and Risk Factors
  • Coronary Interventions and Diagnostics
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiac and Coronary Surgery Techniques
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Abdominal vascular conditions and treatments
  • Renal and Vascular Pathologies
  • Venous Thromboembolism Diagnosis and Management
  • Surgical Simulation and Training
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Atrial Fibrillation Management and Outcomes
  • Vascular anomalies and interventions
  • Cardiovascular Issues in Pregnancy
  • Case Reports on Hematomas
  • Biomarkers in Disease Mechanisms
  • Cardiac Health and Mental Health

National Medical Research Center of Cardiology
2019-2025

Research Medical Center
2023

Institute of Experimental Cardiology
2007-2019

Objective. To evaluate the efficacy and safety of transcatheter aortic valve implantation (TAVI) in patients with severe coronary artery (CA) lesions without prior myocardial revascularization. Material methods. A retrospective study included 270 who underwent TIA 2016-2021. In some (n=200, group 1), TAVI was performed after preliminary percutaneous intervention (PCI), other cases (n=70, 2) — PCI. Propensity score matching performed. Finally, we distinguished 2 groups by 68 patients. These...

10.17116/kardio20251801145 article EN Russian Journal of Cardiology and Cardiovascular Surgery 2025-02-12

Aim. To evaluate myocardial function in different groups of patients with left bundle branch block (LBBB) and the LBBB "model" — right ventricular pacing (RVP). Material methods. Global longitudinal strain (GLS) parameters, such as global constructive work (GCW), wasted (GWW), index (GWI), efficiency (GWE), were measured 25 dilated cardiomyopathy (DCM) (DCM-LBBB group), 20 DCM a narrow QRS complex (DCM-nonLBBB 15 developed after transcatheter aortic valve implantation (TAVI 12 idiopathic...

10.15829/1560-4071-2025-5955 article EN cc-by Russian Journal of Cardiology 2025-03-15

The article presents a clinical case of successful conservative treatment complicated wound the pelvic limb horse. was carried out in stable. Against background systemic antibacterial therapy, regular rinsing canal and abscessed cavities with antiseptic solutions performed to achieve maximum mechanical purification from detritus purulent discharge. By day 42, complete healing achieved restoration functionality. When developing an algorithm for wound, it is necessary take into account...

10.36871/vet.zoo.bio.202501106 article EN Veterinariya Zootekhniya i Biotekhnologiya 2025-01-01

<h3></h3> Представлены данные литературы и собственные исследования о синдроме Такоцубо, относительно редкой патологии сердца, имеющей сходство с острым коронарным синдромом, но без существенного поражения коронарных артерий. Ведущим патогенетическим фактором является повреждающий эффект катехоламинов в условиях стресса вовлечением патогенез сосудов микроциркуляции. Имеется определенная недооценка синдрома Такоцубо как клиницистами, так патологоанатомами, связи чем часть случаев ошибочно...

10.17116/patol2021830115 article RU Russian Journal of Archive of Pathology 2021-01-01

Introduction. Cardiac conduction disturbances with the subsequent need for pacemaker implantation are a major clinical problem in postoperative period of transcatheter aortic valve (TAVI). The aim study. To develop multifactorial models predicting risk developing cardiac and after TAVI early on "training" sample patients an assessment diagnostic accuracy developed model "control" patients. Material methods. study included 337 severe or critical stenosis who underwent from 2021 to 2022...

10.38109/2225-1685-2024-3-50-56 article EN cc-by-nc-sa Eurasian heart journal 2024-10-01

Aim . To study the immediate and short-term outcomes of transcatheter mitral valve edge-to-edge repair with MitraClip NT in patients severe regurgitation as part Russia prospective single-center study. Material methods The included 16 (men, 10; women, 6) mean age 70,1±2,1 years (mean Euroscore II, 6,90±5,56%; STS, 6,33±3,94%). Immediate technical success was defined successful access, delivery, removal device, adequate placing clip(s) to reduce grade 2 or below without need for device-...

10.15829/1560-4071-2022-4689 article EN cc-by Russian Journal of Cardiology 2022-03-12

Nowadays aortic stenosis is the most common valvular pathology in Europe and North America its incidence increases with age. Long asymptomatic period, duration of which varies different patients, main clinical feature this disease. In 80% patients severe onset signs that significantly worsen prognosis, occurs within next 4 years. So, if two-year survival rate period at least 50%, a 5-year symptomatic without surgery, according to some estimates, reduced 15%. Therefore, these do not have any...

10.20996/1819-6446-2015-11-1-53-59 article EN cc-by Rational Pharmacotherapy in Cardiology 2015-01-01

Aim. To develop diagnostic criteria for proximal left bundle branch block (LBBB) based on non-invasive methods and to determine the significance of these in predicting effect cardiac resynchronization therapy (CRT). Material . criteria, 58 patients (21 men, mean age, 76,1±7,1 years) with LBBB occurred immediately after transcatheter aortic valve implantation (TAVI) were included. assess developed second group included 22 (11 57,9±9,3 dilated cardiomyopathy (DCM), who had indications CRT. The...

10.15829/1560-4071-2023-5403 article EN cc-by Russian Journal of Cardiology 2023-09-23

The level of circulating stromal progenitor cells carrying osteonectin (ON), a marker osteogenic differentiation, was evaluated by flow cytometry in blood patients with coronary artery disease (CAD). Ninety-nine CAD were included into the study. Coronary angiography all showed critical stenosis at least 2 arteries or their major branches. control groups 8 without and 19 healthy volunteers. In patients, no lesions bed found angiography. absence volunteers confirmed bicycle stress test....

10.1139/y07-001 article EN Canadian Journal of Physiology and Pharmacology 2007-03-01

Резюме Сложность и вариабельность анатомии митрального клапана (МК) обусловливают необходимость индивидуализированного под0 хода к лечению его патологии, в первую очередь митральной недостаточности. В течение последнего десятилетия разрабатыва0 ются транскатетерные методы лечения патологии МК у пациентов высокого крайне хирургического риска. Рекон0 структивные вмешательства представлены несколькими разновидностями пластики створок кольца МК, а также подклапанного аппарата, которые...

10.36396/ms.2020.16.1.001 article RU Russian Cardiology Bulletin 2020-06-14

Aim. In the issue we report first in Russia experience of transcatheter “valve-invalve” implantation (TVIV) for treatment severe tricuspid stenosis due to structural deterioration surgical bioprosthesis. Material and methods . TVIV was performed 4 high-risk redo patients (1 3 previous sternotomies) various ages across (18-68 years) with Results Technical success achieved 100% cases. Diastolic gradients on valve markedly decreased all patients. Peak transtricuspidal gradient from 20,4 10 mmHg...

10.15829/1560-4071-2019-2-31-37 article EN cc-by Russian Journal of Cardiology 2019-03-07

Aim . To analyze own experience of hybrid and endovascular treatment patients with combined cardiac surgery oncological pathology. Material methods. A retrospective study included 185 (52-92 years) cancer pathology — 15,7% the total number who were operated on at Department Cardiovascular Surgery in 2010-2018 using transcatheter In 135 high-risk patients, implantation aortic valve was performed (35% men, group 1), operations for aneurysm 50 (96% 2). Results Among prostate top concomitant...

10.15829/1728-8800-2019-4-99-104 article EN cc-by CARDIOVASCULAR THERAPY AND PREVENTION 2019-09-04

Aim. To study the effect of transcatheter aortic valve implantation (TAVI), performed by different types prostheses and various surgical access, on prognosis patients with critical stenosis comorbidities. Material methods. Patients (n=130) that had consistently 80 TAVI Edwards transfemoral (n=50) transapical (n=30) as well 50 replacement CoreValve system were included into study. Complications including perioperative mortality, total 30-day post-hospital mortality registered during...

10.20996/1819-6446-2016-12-6-718-724 article EN cc-by Rational Pharmacotherapy in Cardiology 2016-01-01

Aim. To establish the prevalence of atherosclerotic lesions in unpaired visceral artery branches abdominal aorta. explore features clinical presentation, state mucosa upper GI tract. Materials and methods. A total 118 patients with atherosclerosis aorta aged 45 to 89 years were examined. The comparison group included 120 without Patients both groups had coronary atherosclerosis. Ultrasound dopplerography (USDG) as a screening technique, CT angiography, MSCT aortography used verify...

10.31146/1682-8658-ecg-217-9-75-84 article EN cc-by Experimental and Clinical Gastroenterology 2024-01-17

Main causes of secondary hypertrophic cardiomyopathy include acromegalic cardiomyopathy. Heart damage in patients with the acromegaly is mediated both by direct action growth hormone and insulin-like factor-1, increased deposition collagen lymphomononuclear cells myocardium, which leads to architectural changes, disturbances fluid electrolyte balance, severe left ventricular myocardial hypertrophy, diastolic systolic dysfunction chronic heart failure. This article presents world's first...

10.26442/00403660.2024.04.202682 article EN cc-by-nc Terapevticheskii arkhiv 2024-05-02

Transcatheter aortic valve implantation (TAVI) is a technology that allows effective surgical treatment for stenosis. One of the causes stenosis congenital pathology characterized by bicuspidal structure valve. This condition has long been considered an absolute contraindication to TAVI, however, emergence new generations prostheses, experience, as well deep understanding anatomy bicuspid valves perform TAVI in such patients. article discusses existing classifications valves, features...

10.29001/2073-8552-2024-39-2-28-35 article EN Siberian Journal of Clinical and Experimental Medicine 2024-07-09

10.30842/ielcp2306901528051 article EN Indo-European linguistics and classical philology 2024-01-01

To search for predictors of adverse cardiovascular events after edge-to-edge transcatheter mitral valve repair (TMVR) in patients with severe regurgitation (MR) various origins an assessment structural and functional remodeling the heart left ventricular (LV) contractile function.

10.18087/cardio.2024.9.n2699 article EN cc-by Kardiologiia 2024-09-30

Aim. To evaluate immediate single-center results of transcatheter aortic valve implantation (TAVI) with use novel self-expanding bioprosthesis Acurate neo. Material and methods. TAVI procedure was performed in 69 high-tointermediate surgical risk patients (mean age 76,8±6,1years, 31 males, 68 females) severe calcified stenosis diverse comorbidity. Concomitant coronary artery disease observed 43 (62%), atrial fibrillation 23 (33%), diabetes mellitus type 2 26 (38%) patients. Median Euroscore...

10.15829/1560-4071-2019-8-59-64 article EN cc-by Russian Journal of Cardiology 2019-09-20

The authors present up-to-date review of clinical pathophysiology aortic stenosis (AS) based on differentiation its haemodynamic patterns, and some actual issues instrumental diagnostics classification AS. variety presentations AS is diverse combination pathological changes haemodynamics. In Russian cardiology, there no clear pathophysiological despite relevance under the progress surgical transcatheter treatment suggest pilot which includes 6 types (0-5) different following variables: left...

10.20996/1819-6446-2020-10-06 article EN cc-by Rational Pharmacotherapy in Cardiology 2020-10-18
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