A5027946371- Cervical Cancer and HPV Research
- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Molecular Biology Techniques and Applications
- Genital Health and Disease
- Cutaneous Melanoma Detection and Management
- Reproductive tract infections research
- Uterine Myomas and Treatments
- Nonmelanoma Skin Cancer Studies
- Neonatal Respiratory Health Research
- Cancer-related molecular mechanisms research
- Cutaneous lymphoproliferative disorders research
- Endometriosis Research and Treatment
- Cancer Risks and Factors
- Cancer and Skin Lesions
- Gynecological conditions and treatments
- Urological Disorders and Treatments
- Urinary Bladder and Prostate Research
- Surgical Sutures and Adhesives
- Hepatitis B Virus Studies
- Minimally Invasive Surgical Techniques
- AI in cancer detection
- Infant Development and Preterm Care
- Sexual function and dysfunction studies
- Global Cancer Incidence and Screening
European Institute of Oncology
2017-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2012-2024
University of Sassari
2020-2023
Ripamonti
2019-2023
University of Pavia
2011-2019
Policlinico San Matteo Fondazione
2011-2016
Clinica Valle Giulia
2015
Weatherford College
2014
ABSTRACT This study assessed the accuracy of high-risk human papillomavirus testing BD Onclarity HPV (Onclarity) assay on vaginal self-collected FLOQSwab versus cervical samples to ensure similar detect intraepithelial neoplasia. Testing was performed two automated platforms, Viper LT and COR, evaluate effect machine using self-samples analyze influence collection, transport, freezing-unfreezing results. A sample were collected from 300 women. The first tested LT, second swab frozen...
Whereas HPV16 and HPV18 have been the focus in current risk-based cervical cancer screening algorithms using HPV genotype information, mounting evidence suggests that oncogenic types such as HPV31, 33, 52 58 pose a ≥CIN3 risk equivalent to or greater than of HPV18, combined HPV31 HPV33 rivals even women above 30 years age. Here, we evaluate baseline CIN2 CIN3 by colposcopy referral population from Denmark Italy. In total, 655 were enrolled upon after positive sample. All samples analyzed...
The accuracy of available HPV molecular assays on self-samples needs to be evaluated as compared clinician-collected samples. This pilot study aimed investigate the BD Onclarity™ assay vaginal and first-void urine Sixty-four women referred colposcopy for cervical dysplasia performed a self-collection provided sample, after informed consent. A specimen was collected during clinician examination. All samples were tested using Viper™ LT System. Overall positive agreement (OPA) between...
Quality Control (QC) and Assurance (QA) principles are essential for effective cervical cancer prevention. Being a crucial diagnostic step, colposcopy’s sensitivity specificity improvements strongly advocated worldwide since inter- intra-observer differences the main limiting factors. The objective of present study was evaluation colposcopy accuracy through results QC/QA assessment from survey in Italian tertiary-level academic teaching hospitals. A web-based, user-friendly platform based on...
The association between vulvodynia and interstitial cystitis/bladder pain syndrome (IC/BPS), a chronic, debilitating disease of unknown etiology, may involve sex hormone-dependent mechanisms regulating vulvo-vaginal health. We aimed to prospectively investigate the effects 12 weeks local estrogen therapy (LET) on urinary/bladder sexual symptoms in premenopausal women with IC/BPS. Thirty-four (mean age: 36.1 ± 8.4) diagnosed IC/BPS were treated vulvo-vaginally three-times/week estriol 0.5 mg...
Assessing lymph node metastasis is crucial in determining the optimal therapeutic approach for endometrial cancer (EC). Considering impact of lymphadenectomy, there an urgent need a cost-effective and easily applicable method to evaluate risk cases sentinel (SLN) biopsy failure. This retrospective monocentric study enrolled EC patients, who underwent surgical staging with nodal assessment. Data concerning demographic, clinicopathological, ultrasound, characteristics were collected from...
Vulvar melanoma (VM) is rare and often diagnosed late. Dermoscopy may aid in its recognition, differentiating VM from other more common vulvar lesions, such as melanosis naevi. However, little known about the dermoscopic features of thin VM. To retrospectively analyse a series histopathologically VMs to highlight their most suggestive features. A multicentre, retrospective study was conducted, including proven VMs, either intraepidermal or with Breslow thickness ≤ 0.5 mm, during period...
Objective The aim of the study was to investigate distribution high-risk (HR) human papillomavirus (HPV) genotypes and role multiple infection in preneoplastic neoplastic cervical lesions, according histology, age, number per infection. Materials Methods Nine hundred eighty-eight women affected by known HPV-related lesions attending European Institute Oncology, Milan, Italy, from December 2006 2014, were selected for a cross-sectional study. Prevalence HPV calculated histology Univariate...
ABSTRACT The introduction of self‐sampling in cervical cancer screening has raised the importance HPV test validation on self‐collected samples. This study aimed to evaluate clinical accuracy OncoPredict Screening (SCR) assay vaginal and first‐void urine (FVU) samples, relative specimens, using VALHUDES Framework. FVU self‐samples followed by a clinician‐collected brushing were collected from 500 women referred colposcopy tested SCR assay. demonstrated sensitivity detect intraepithelial...
"Long-term risk of malignancy in the neovagina created using colon graft vaginal agenesis – A case report." Journal Obstetrics and Gynaecology, 35(5), pp. 543–544
The prevalence of reaches up to 5% in women younger than 40 years. Therefore, the fertility preservation should be goal clinical practice with desire pregnancy and low-risk features. aim this study is compare oncological reproductive outcomes different hormonal therapies FST EC. A retrospective single-center recruiting patients presumed FIGO STAGE IA endometrioid G1 EC from 2005 2020 was performed. We assessed for three therapeutic options: GnRHa + LNG-IUD vs. MA MET. In total, 75 were...
The aim of the study was to evaluate association between size cervical lesions as detected by colposcopy and multiple human papillomavirus (HPV) infection in subjects with intraepithelial neoplasia (CIN).A case series 898 CIN diagnosed histopathology infected high-risk HPV. Human genotypes were identified using INNO-LIPA genotyping system.The rates 1, 2, 3+ 53.1% (477/898), 14.1% (127/898), 32.7% (294/898), respectively. Among loop electrosurgical excision procedure or cold-knife conization,...
The aim of the study was to evaluate outcome persistent (≥2 years) low-grade cervical intraepithelial neoplasia (CIN 1) treated with loop electrosurgical excision procedure (LEEP).A 252 subjects biopsy-confirmed CIN 1 diagnosed after squamous lesions or atypical undetermined significance on Papanicolaou test and LEEP. Post-LEEP follow-up cytological, colposcopic, molecular diagnostic examinations were scheduled at 6 months, year, yearly thereafter.The enrolled had a total number 1,008 visits...
Objective Many methods are available today for human papillomavirus (HPV) testing; they differ technology, targets, and information on the genotypes detected. In this study, we evaluated performance of Onclarity HPV assay in detection follow-up cervical preneoplastic lesions. Materials Methods One hundred sixty-seven women referred to European Institute Oncology, Milan, treatment lesions were enrolled. We investigated utility extended genotyping test management intraepithelial neoplasia...