A5078829324- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Tracheal and airway disorders
- Cardiac Arrhythmias and Treatments
- Congenital Diaphragmatic Hernia Studies
- Aortic Disease and Treatment Approaches
- Pulmonary Hypertension Research and Treatments
- Coronary Artery Anomalies
- Renal and Vascular Pathologies
- Kawasaki Disease and Coronary Complications
- Mechanical Circulatory Support Devices
- Cardiac electrophysiology and arrhythmias
- Cardiac Valve Diseases and Treatments
- Liver Disease and Transplantation
- Cardiovascular Issues in Pregnancy
- Cardiovascular Effects of Exercise
- Congenital Anomalies and Fetal Surgery
- Vascular anomalies and interventions
- Inflammasome and immune disorders
- Cardiomyopathy and Myosin Studies
- Autoimmune and Inflammatory Disorders Research
- Polysaccharides and Plant Cell Walls
- Blood Coagulation and Thrombosis Mechanisms
- Cardiovascular Conditions and Treatments
- Systemic Lupus Erythematosus Research
Government Medical College
2025
Hospital for Sick Children
2024
Kyushu University
2014-2024
Kyushu University Hospital
2023
Kyushu Institute of Information Sciences
2021
University Hospital of Zurich
2012
Left ventricular non-compaction (LVNC) is a cardiomyopathy characterized by prominent trabeculae and intertrabecular recesses. We present the cases of 3 girls with sameryanodine receptor type 2(RYR2) mutation who had phenotypes both catecholaminergic polymorphic tachycardia (CPVT) LVNC.
Right ventricular (RV) hemodynamic performance determines the prognosis of patients with RV pressure overload. Using ultrafast ultrasound, natural wave velocity (NWV) induced by cardiac valve closure was proposed as a new surrogate to quantify myocardial stiffness.
Abstract Objective Congenital portosystemic venous shunt (CPSVS) is a rare vascular malformation with high risk of mortality from pulmonary arterial hypertension (PAH), but the treatment outcome CPSVS closure remains elusive. Our aim was to investigate clinical features and establish optimal management or without PAH. Methods Twenty‐four patients treated in Kyushu University Hospital between 1990 2015 were enrolled this study. The divided into PAH group ( n = 9) non‐PAH 15). Clinical...
Abstract Background Loeys–Dietz syndrome, also known as Marfan syndrome type II, is a rare connective tissue disorder caused by dominant mutations in transforming growth factor - beta receptors ( TGFBR1 and 2 ). Case presentation We report 7-year-old Japanese boy with who carried novel, de novo missense mutation TGFBR2 (c.1142g > c, R381P). He showed dysmorphic faces skeletal malformations that were typical previous cases Loeys-Dietz syndrome. The cardiac studies disclosed the presence of...
Abstract Aims Interatrial shunting (IAS) reduces left atrial pressure in patients with heart failure. Several clinical trials reported that IAS improved the New York Heart Association score and exercise capacity. However, its effects on haemodynamics vary depending shunt size, cardiovascular properties, stressed blood volume. To maximize benefit of IAS, quantitative prediction under individual is essential. The generalized circulatory equilibrium framework determines as intersection cardiac...
Objective. Chronic inflammation plays a key role in the development of atherosclerosis. Early progression atherosclerosis has been reported patients with RA. Cryopyrin-associated periodic syndromes (CAPS) are autosomal dominant autoinflammatory disorders caused by heterozygous NLRP3 gene mutations. infantile neurological cutaneous and articular (CINCA) syndrome is most severe form CAPS display early onset rash, fever, uveitis joint manifestations. However, there no previous report on CAPS....
Introductions: Pulmonary regurgitation is a diastolic phenomenon but little known of the impact RV-PA conduit interventions on RV function. We measured acute effects PPVI or stent implantation relaxation with high-fidelity pressure catheters. Methods: Right and left heart measurements Millar Mikro-Cath catheters in children undergoing intervention, who had also an MRI. The time constant (RV-tau) was calculated as monoexponential decay interval between at dP/dt min (P 0 ) to when fell 10% P ....
Introduction: Congenital portosystemic shunt (CPSS) is a rare vascular malformation which forms shunts between the portal and systemic veins. Pulmonary arterial hypertension (PAH) in CPSS patients heightens mortality risk. Research Questions: It remains unclear patients’ characteristics are associated with developing PAH individuals. Additionally, it not yet determined whether closure improves prognosis of these patients. Methods: This single-center case-control study explored data from 31...
Thrombotic microangiopathies (TMA) are microvascular occlusive disorders characterized by systemic or intrarenal platelet aggregation, thrombocytopenia, and red cell fragmentation. Post-operative TMA mostly occurs in adult patients with cardiovascular surgery, the distinct pathophysiology from classical thrombotic thrombocytopenic purpura (TTP) although exact remains unclear.A one-month-old infant developed after initial surgery of double outlet right ventricle. ADAM metallopeptidase...
Congenital diaphragmatic hernia (CDH) is a relatively rare malformation, but it has high mortality rate. Its association with congenital heart disease lowers survival rate due to severe acidosis and desaturation caused by persistent pulmonary hypertension of the neonate. We describe herein case CDH transposition great arteries intact ventricular septum, in patient who was prenatally diagnosed, managed extracorporeal oxygenation (ECMO) support successfully treated both repair Jatene...
Purpose: Pulmonary valve replacement (PVR) improves right ventricular (RV) function in patients with tetralogy of Fallot (TOF). However, the impact PVR on left (LV) and mechanism improvement are still unclear. The purpose this study is to clarify LV mechanical efficiency adult TOF. Methods: Fourteen TOF (age 30.1±11.5 years) who underwent for significant pulmonary insufficiency were enrolled study. We measured end-diastolic volume index (LVEDVI), end-systolic (LVESVI), contractility...