A5102025906- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Pulmonary Hypertension Research and Treatments
- Cardiac Arrhythmias and Treatments
- Coronary Artery Anomalies
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiovascular Issues in Pregnancy
- Renal and Vascular Pathologies
- Mechanical Circulatory Support Devices
- Cardiac pacing and defibrillation studies
- Tracheal and airway disorders
- Aortic Disease and Treatment Approaches
- Ultrasound in Clinical Applications
- Pediatric Hepatobiliary Diseases and Treatments
- Congenital Anomalies and Fetal Surgery
- Congenital Diaphragmatic Hernia Studies
- Obstructive Sleep Apnea Research
- Cardiovascular Effects of Exercise
- Retirement, Disability, and Employment
- Acute Myocardial Infarction Research
- Vascular anomalies and interventions
University Health Network
2021-2025
Kyushu University Hospital
2015-2025
Mount Sinai Hospital
2021-2024
University of Toronto
2018-2024
Fukuoka Children's Hospital and Medical Center for Infectious Diseases
2023-2024
Kyushu University
2013-2024
Toronto General Hospital
2018-2020
San Diego Cardiac Center
2020
Kyushu Hospital
2008
Background Identification of individuals at risk for major adverse cardiovascular events is essential contemporary management patients with repaired tetralogy Fallot. We sought to identify clinical and magnetic resonance imaging (CMR) predictors outcomes in Methods Children adults prospectively enrolled the CORRELATE (Comprehensive Outcomes Registry Late After Tetralogy Fallot Repair) registry followed North American, European, Asian centers were studied. All had least moderate pulmonary...
The relationship between right ventricular (RV) fibrosis and heart reverse remodelling following pulmonary valve replacement (PVR) has not been well studied in adults with repaired tetralogy of Fallot (rTOF). Our aims were to histologically quantify RV explore the severity cardiac post-PVR.Adults rTOF pre-PVR cardiovascular (CMR) imaging consented procurement muscle during PVR. Samples stained picrosirius red collagen volume fraction. Clinical data at baseline last follow-up reviewed....
Right ventricular (RV) failure and dyssynchrony are strong determinants of prognosis in patients with adult congenital heart disease (ACHD). The aim this study was to investigate the relationship between interventricular (IVD) using cine-tagged magnetic resonance imaging (MRI) RV dysfunction ACHD patients.Sixty-seven (38 repaired tetralogy Fallot; 22 atrial septal defect; seven defect) underwent tagging MRI. Time curves myocardial circumferential strains for left (LV) free walls were...
Patients with Fontan circulation are known to be at high risk for developing atrial tachyarrhythmias (AAs). Our objective was examine the efficacy and safety of amiodarone in management ATs adult patients.Primary outcomes this single-centre, retrospective study included freedom from AAs incidence adverse effects on patients. Heart failure (HF) events composite death any cause, revision heart transplantation were evaluated as secondary outcomes. Predictors HF discontinuing also evaluated.A...
We measured right ventricular (RV) strain by applying a novel postprocessing technique to conventional short-axis cine magnetic resonance imaging in the repaired tetralogy of Fallot (TOF) and investigated whether pulmonary valve replacement (PVR) changes RV strain. Twenty-four patients with TOF who underwent PVR 16 healthy controls were enrolled. Global maximum minimum principal strains (GPSmax, GPSmin) global circumferential longitudinal (GCS, GLS) from images reconstructed radially along...
Objectives Although a life-preserving surgery for children with single ventricle physiology, the Fontan palliation is associated striking morbidity and mortality advancing age. Our primary objective was to evaluate impact of non-invasive, external, thoraco-abdominal ventilation on pulmonary blood flow (PBF) cardiac output (CO) as measured by cardiovascular magnetic resonance (CMR) imaging in adult subjects. Methods Adults dominant left post-Fontan (lateral tunnel or extracardiac connections)...
Pulmonary regurgitation (PR) is a risk factor for sudden cardiac death in adult patients with repaired tetralogy of Fallot (TOF). However, transthoracic echocardiography (TTE) cannot fully visualize the pulmonary valve (PV) and PR. We investigated whether intracardiac (ICE) could PV PR better than TTE. Thirty TOF (mean age 33 ± 15 years) scheduled catheterization underwent ICE. The visualization severity were classified into three grades. ICE depicted TTE (ICE vs. TTE: not visualized,...
rTOF, repaired tetralogy of Fallot SAS, specific activity scale VO2, oxygen consumption
Abstract A long duration of Fontan circulation can cause fibrosis, cirrhosis the liver and cancer. There have been some reports hepatocellular carcinoma occurring after procedure (FP), we encountered a case intrahepatic cholangiocarcinoma (ICC) FP. We herein report 33-year-old man who developed ICC receiving At five years age, patient underwent original 16 years he received total cavopulmonary connection conversion. Sixteen later, suffered right heart failure. Thereafter his symptoms showed...