A5100321863- Meningioma and schwannoma management
- Vestibular and auditory disorders
- Sinusitis and nasal conditions
- Ear and Head Tumors
- Head and Neck Surgical Oncology
- Ear Surgery and Otitis Media
- Cerebral Venous Sinus Thrombosis
- Neurofibromatosis and Schwannoma Cases
- Pituitary Gland Disorders and Treatments
- Facial Nerve Paralysis Treatment and Research
- Pancreatic and Hepatic Oncology Research
- Allergic Rhinitis and Sensitization
- Tumors and Oncological Cases
- Neuroendocrine Tumor Research Advances
- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal disorders and treatments
- Oral and Maxillofacial Pathology
- Medical Imaging Techniques and Applications
- Metastasis and carcinoma case studies
- Health and Wellbeing Research
- Gastric Cancer Management and Outcomes
- Hearing, Cochlea, Tinnitus, Genetics
- Salivary Gland Tumors Diagnosis and Treatment
- Teratomas and Epidermoid Cysts
- Respiratory and Cough-Related Research
Jeonbuk National University
2012-2024
Chonbuk National University Hospital
2014-2024
Korea Bio Polytechnic College
2020-2024
Yeungnam University College
2022
Yeungnam University
1996-2022
GTx (United States)
2022
In-Q-Tel
2022
Hankyong National University
2020
Catholic University of Korea
1999-2020
Sangji University
2020
Pancreatic stellate cells (PSCs) differentiate into cancer-associated fibroblasts (CAFs) that produce desmoplastic stroma, thereby modulating disease progression and therapeutic response in pancreatic ductal adenocarcinoma (PDA). However, it is unknown whether CAFs uniformly carry out these tasks or if subtypes of with distinct phenotypes PDA exist. We identified a CAF subpopulation elevated expression α-smooth muscle actin (αSMA) located immediately adjacent to neoplastic mouse human...
To evaluate prospectively the accuracy of integrated positron emission tomography (PET) and computed (CT) with use fluorodeoxyglucose (FDG), compared that stand-alone CT, for preoperative staging non-small cell lung cancer, surgical histologic findings used as reference standard.Institutional review board approval patient informed consent were obtained. From November 2003 to February 2004, 106 patients (78 men, 28 women; mean age, 56 years) cancer underwent curative resection (tumor lymph...
Glycosylation alterations are indicative of tissue inflammation and neoplasia, but whether these contribute to disease pathogenesis is largely unknown. To study the role glycan changes in pancreatic disease, we inducibly expressed human fucosyltransferase 3 β1,3-galactosyltransferase 5 mice, reconstituting sialyl-Lewisa, also known as carbohydrate antigen 19-9 (CA19-9). Notably, CA19-9 expression mice resulted rapid severe pancreatitis with hyperactivation epidermal growth factor receptor...
OBJECTIVE Advances in neuroimaging techniques have led to the increased detection of asymptomatic intracranial meningiomas (IMs). Despite several studies on natural history IMs, a comprehensive evaluation method for estimating growth potential these tumors, based relative weight each risk factor, has not been developed. The aim this study was develop weighted scoring system that estimates rapid tumor aid treatment decision making. METHODS authors performed retrospective analysis 232 patients...
Of 149 patients with suspected cytomegalovirus (CMV) gastrointestinal disease, 51 (36%) confirmed cases, 6 (4%) probable and 64 (45%) instances of non-CMV disease were analyzed using the CMV antigenemia assay; 22 (5%) indeterminate excluded. The sensitivity specificity assay (defined as detection > or =1 positive cells per 200,000 leukocytes) for diagnosis 54% (95% confidence interval, 41%-68%) 88% 77%-94%), respectively.
This study evaluated the usefulness of T2-weighted and gadolinium-enhanced T1-weighted magnetic resonance (MR) images correlated with patients' menopausal status in assessing depth myometrial invasion stage I endometrial carcinoma. MR 46 patients carcinoma were retrospectively reviewed. Twenty-five premenopausal, 21 postmenopausal. The staging accuracy without regard to was 59% for 61% images. However, when separately premenopausal postmenopausal patient groups, imaging had an 80% group 81%...
Comprehensive knowledge of the anatomical features trigeminal schwannomas (TSs) is essential in planning surgery to achieve complete tumor resection. In current report, we propose a modified classification TSs according their location origin, shape, and extension into adjacent compartment, discuss appropriate surgical strategies with this classification.We retrospectively analyzed 49 patients TS who were treated surgically by single neurosurgeon at Asan Medical Center between 1993 2013.There...
To assess the impact of complete resection craniopharyngioma (CP) in adults on oncologic and functional outcomes.We retrospectively analyzed 82 patients with CP who were surgically treated by same neurosurgeon at our institution between January 1994 December 2012.Gross total (GTR) was achieved 71 (86.6%), near (NTR) 7 (8.5%), subtotal (STR) 3 (3.7%). The disease-specific overall survival rate 100% exclusion 2 surgery-related mortalities. recurrence 12.2% (10 patients), however according to...
The subtype of eccrine carcinoma known as squamoid ductal (SEDC) is rare; only 38 cases, including 6 cases in the ear, have been documented literature. This may be first case to focus on fact that SEDC, located within dermal and subcutaneous layers, spares epidermis histopathologically, which can cause clinicians confuse SEDC with acute perichondritis.
The incidence of fungal sinusitis is increasing; however, its pathophysiology has not been investigated previously. We investigate the effect periodontitis on over a 12-year follow-up period using nationwide population-based data.The group was randomly selected from National Health Insurance Service database. non-periodontitis obtained by propensity score matching considering several variables. primary end point diagnosis sinonasal balls (SFBs) and invasive (IFS).The groups included 12,442...
There have been no definite indications for additional surgical resection after endoscopic submucosal dissection (ESD) of invasive colorectal cancer (SICC). The aims this study were to evaluate the feasibility ESD nonpedunculated SICC and determine need subsequent surgery ESD.A total 150 patients with in resected specimens analyzed. Among them, 75 underwent ESD. Clinical outcomes histopathological risk factors lymph node (LN) metastasis evaluated.The en-bloc complete (R0) rates 98% (147/150)...
A complex relationship exists between chronic kidney disease-mineral and bone disorder (CKD-MBD) adverse outcomes among dialysis patients. This study aimed to report the prevalence of CKD-MBD examine impact achieving target parameters on morbidity mortality one year after peritoneal (PD) initiation.In this retrospective cohort study, patients electively initiated PD were followed up for year. Laboratory collected 4-6 months initiation was determined based Kidney Disease Outcomes Quality...
Study Objectives: To evaluate the risk of insomnia in patients with sudden sensorineural hearing loss (SSNHL).Methods: A retrospective propensity score-matched cohort study was conducted using a nationwide representative sample from National Sample Cohort 2002-2013 data Korea Health Insurance Service.The SSNHL group (n = 631) included diagnosed between January 2002 and December 2005.The comparison (4 controls for every patient SSNHL, n 2,524) selected score matching, according to...
Silibinin, has been investigated for its potential benefits and mechanisms in addressing vanadium pentoxide (V2O5)-induced pulmonary inflammation. This study explored the anti-inflammatory activity of silibinin elucidate by which it operates a mouse model vanadium-induced lung injury.