Zhongqiang Li

ORCID: 0000-0001-6962-5146
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About
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Research Areas
  • Dental Radiography and Imaging
  • Laser Applications in Dentistry and Medicine
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Optical Imaging and Spectroscopy Techniques
  • Spectroscopy and Chemometric Analyses
  • Image and Signal Denoising Methods
  • Dental materials and restorations
  • Molecular Biology Techniques and Applications
  • Advanced Optical Imaging Technologies
  • Photonic and Optical Devices
  • Advanced X-ray and CT Imaging
  • Endodontics and Root Canal Treatments
  • Medical Image Segmentation Techniques
  • Image Processing Techniques and Applications
  • Advanced Sensor and Control Systems
  • Advanced Fiber Optic Sensors
  • Photoacoustic and Ultrasonic Imaging
  • Visual perception and processing mechanisms
  • Advanced Data Compression Techniques
  • Plant and Fungal Species Descriptions
  • Power Systems and Technologies
  • Nanoplatforms for cancer theranostics
  • Cancer therapeutics and mechanisms
  • Digital and Cyber Forensics
  • Advanced Data and IoT Technologies

Ocean University of China
2025

Louisiana State University
2018-2024

Johns Hopkins University
2024

Johns Hopkins Medicine
2024

Linyi People's Hospital
2022

Louisiana State University Agricultural Center
2021

Shandong University
2020

Chongqing Technology and Business University
2015

Vestfold University College
2015

Systems Technology (United States)
2015

Adaptive optics (AO) has been instrumental in ophthalmic imaging, by correcting wavefront aberrations ocular and achieving diffraction-limited resolution. Current state-of-the-art AO retinal imaging systems use mirror-based to avoid surface reflection chromatic aberrations, requiring a large system footprint with long focal length spherical mirrors. Here we report compact refractive lens-based scanning laser ophthalmoscopy (SLO) simultaneous dual channel fluorescence capacity mouse retina....

10.1101/2025.03.31.645335 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2025-04-02

Abstract Cracked teeth are the third most common cause of tooth loss, but there is no reliable imaging tool for diagnosis cracks. Here, we demonstrate feasibility indocyanine green near‐infrared fluorescence (ICG‐NIRF) dental detection enamel cracks and enamel–dentin in vitro first (ICG‐NIRF‐I, 700–950 nm) second (ICG‐NIRF‐II, 950–1700 windows with transmission excitation light, compared ICG‐NIRF conventional NIR illumination‐II (NIRi‐II) X‐ray imaging. Dentin were detected by CT scan, while...

10.1111/nyas.14374 article EN Annals of the New York Academy of Sciences 2020-06-09

The plant homeodomain (PHD) finger is identified in many chromatin-binding proteins, and functions as a 'reader' that recognizes specific epigenetic marks on histone tails, bridging transcription factors their associated complexes to chromatin, regulating gene expression. PHD finger-containing proteins perform biological are involved human diseases including cancer. PHF14 predicted code for protein with multiple fingers. However, its function unidentified. aim of this study characterize...

10.1093/abbs/gmt055 article EN Acta Biochimica et Biophysica Sinica 2013-05-21

Abstract Indocyanine green (ICG) has been widely used in medical imaging, such as retinal angiography. Here, we describe a pilot ex vivo study of ICG‐assisted near‐infrared fluorescence (NIRF) dental imaging the first (700–950 nm for ICG‐NIRF‐I) and second (1000–1700 ICG‐NIRF‐II) NIR windows using human extracted teeth; our is compared with traditional prevalent X‐ray II illumination (NIRi‐II, 1310 nm) without ICG enhancement. The results show that much better contrast both NIRi‐II (by...

10.1111/nyas.14086 article EN Annals of the New York Academy of Sciences 2019-04-05

SUMMARY The present study aims to evaluate the antiparasitic activity of active components from Costus speciosus against Ichthyophthirius multifiliis . Bioassay-guided fractionation was employed identify compounds C. yielding 2 bioactive compounds: Gracillin and Zingibernsis newsaponin. In-vitro assays revealed that newsaponin could be 100% effective I. at concentrations 0·8 4·5 mg L −1 , with median concentration (EC 50 ) values 0·53 3·2 respectively. All protomonts encysted tomonts were...

10.1017/s0031182014001358 article EN Parasitology 2014-08-20

Abstract Current dental diagnosis, especially tooth abnormalities, relies largely on X‐ray–based imaging, a technique that requires specialized skills and suffers from ionizing radiation. Here, we present pilot study in rats of an efficient, ionizing‐radiation–free easy‐to‐use alternative for imaging. Postnatal at different ages were injected with indocyanine green molars imaged by laboratory‐designed endoscopic near‐infrared (NIR) imaging system. The results indicate the NIR can be used to...

10.1111/nyas.13674 article EN Annals of the New York Academy of Sciences 2018-05-08

Abstract X-ray-based imaging, including computed tomography, plays a crucial role in the diagnosis and surgery of impacted teeth that affects over 25% human population. But greatest disadvantage this technique is ionizing radiation risk to patients. Here we describe completely ionizing-radiation-free vivo near-infrared (NIR) fluoresence dental imaging with indocyanine green (ICG) agent has rarely been applied imaging. Our method can acquire structure images within short period (only 10...

10.1038/s41598-019-44660-y article EN cc-by Scientific Reports 2019-06-03

Abstract Background Breast cancer poses a significant health risk to women worldwide, with approximately 30% being diagnosed annually in the United States. The identification of cancerous mammary tissues from non-cancerous ones during surgery is crucial for complete removal tumors. Results Our study innovatively utilized machine learning techniques (Random Forest (RF), Support Vector Machine (SVM), and Convolutional Neural Network (CNN)) alongside Raman spectroscopy streamline hasten...

10.1186/s12575-024-00255-0 article EN cc-by Biological Procedures Online 2024-09-12

Cell-laden printing is the most commonly used approach in 3D bioprinting. One of major drawbacks cell-laden that cell viability highly affected by extrusion pressure and shear force process. We present a new cell-deposition method using superabsorbent capability printed scaffolds with four ink formations: 20:10 nanocrystal/alginate (NCA 20/10), nanofiber/alginate (NFA 20:02 20/02) 20/02). Limited pores were observed from surface inherent NCA NFA scaffolds, which may limit numbers cells to...

10.1088/2057-1976/ab8fc6 article EN Biomedical Physics & Engineering Express 2020-05-04

Dental diseases significantly impact the quality of life and human populations; current X-ray diagnostic dental imaging method may also bring potential health risks to humans. This study used extracted teeth rats as animal model test a new near-infrared (NIR) fluorescence system with painless mouthwash for administering indocyanine green (ICG). Our results show that delivery ICG enables better image contrast than subcutaneous injection at short time (1-10 minutes after administration):...

10.1109/jstqe.2020.2995659 article EN IEEE Journal of Selected Topics in Quantum Electronics 2020-05-21

In this study, we used rat animal model to compare the efficiency of indocyanine green (ICG)-assisted dental near-infrared fluorescence imaging with X-ray imaging, and optimized window for both unerupted erupted molars. The results show that morphology structures was observed clearly from ICG-assisted images (especially through endoscope). A better image contrast easily acquired at short windows (<10 minutes) For molars, there is another (48-96 hours) a prominent glow-in-the-dark effect:...

10.1002/jbio.201960232 article EN Journal of Biophotonics 2020-02-28

Abstract Background It is common for children to accidentally ingest chemical drugs with different degrees of toxicity. Meperfluthrin a highly effective and easy-to-use pyrethroid pesticide low widely used in electric mosquito coils. This type coil daily life, which increases the chance exposure among and, consequently, may lead accidental ingestion. There are only few reports meperfluthrin poisoning causing lung injury children. We report rare clinical case wherein child ingested orally....

10.1186/s12887-022-03117-4 article EN cc-by BMC Pediatrics 2022-01-17

The stereo vision results from the interaction between geometrical optics and visual psychology. Large depth will bring discomforts for of ghosting flicker. relevance ratio jumping out (RJD) electroencephalogram (EEG) gravity frequency (GF) was explored to reflect human health under different three-dimensional (3D) information (mainly negative disparity) displayed on a television (3D-TV) with shutter glasses. EEG obtained 10 volunteers when they were watching 3D film segments disparities....

10.1142/s179354581550011x article EN cc-by Journal of Innovative Optical Health Sciences 2014-10-16
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