A5002965139- Toxic Organic Pollutants Impact
- Effects and risks of endocrine disrupting chemicals
- Per- and polyfluoroalkyl substances research
- Environmental Toxicology and Ecotoxicology
- Air Quality and Health Impacts
- Mercury impact and mitigation studies
- Reproductive biology and impacts on aquatic species
- Pharmaceutical and Antibiotic Environmental Impacts
- Heavy Metal Exposure and Toxicity
- Fatty Acid Research and Health
- Pesticide Exposure and Toxicity
- Birth, Development, and Health
- Atmospheric chemistry and aerosols
- Carcinogens and Genotoxicity Assessment
- Isotope Analysis in Ecology
- Nutritional Studies and Diet
- Marine animal studies overview
- Fish Ecology and Management Studies
- Mycotoxins in Agriculture and Food
- Climate Change and Health Impacts
- Immunotoxicology and immune responses
- Aquaculture Nutrition and Growth
- Pharmacological Effects and Toxicity Studies
- Marine and coastal ecosystems
- Health, Environment, Cognitive Aging
Norwegian University of Life Sciences
2014-2024
657 Oslo
2020
Norwegian Veterinary Institute
2008-2012
In the European regulatory context, rodent in vivo studies are predominant source of neurotoxicity information. Although they form a cornerstone neurotoxicological assessments, costly and topic ethical debate. While public expects chemicals products to be safe for developing mature nervous systems, considerable numbers commerce have not, or only limited extent, been assessed their potential cause neurotoxicity. As such, there is societal push toward replacement animal models with vitro...
Abstract Ionizing radiation is known to cause DNA damage, yet the mechanisms underlying potential transgenerational effects of exposure have been scarcely studied. Previously, we observed in offspring zebrafish exposed gamma during gametogenesis. Here, hypothesize that these are accompanied by changes methylation possibly inherited subsequent generations. We assessed F1 embryos (5.5 hours post fertilization) with whole genome bisulfite sequencing following parental 8.7 mGy/h for 27 days and...
Perfluoroalkyl substances (PFASs) are used in a wide range of consumer products, including ski such as waxes. However, there is limited knowledge on the release PFASs from products into environment and resultant uptake biota transport food webs. We investigated levels, patterns, biomagnification soil, earthworms (Eisenia fetida), Bank voles (Myodes glareolus) skiing area Trondheim, Norway. In general, was higher PFAS levels compared to reference with no activities. The dominated by...
The aim of the present study was to investigate effects defined mixtures polycyclic aromatic hydrocarbons (PAHs) and perfluoroalkyl substances (PFASs), at low, environmentally relevant (1× = L), or high (20× H) doses, on biological responses in Atlantic cod (Gadus morhua). To this end, farmed juvenile were exposed day 0 7 via intraperitoneal (i.p.) injections, a two-week vivo experiment. In total, there 10 groups fish (n 21-22): two control groups, four separate exposure PAH PFAS (L, H),...
In the present study, we investigated dopaminergic and steroid hormone systems of A/J mice fed environmentally relevant concentrations a perfluoroalkyl substance (PFAS) mixture over period 10 weeks. The PFAS was chosen based on measured in earthworms at Norwegian skiing area (Trondheim) consisted eight different PFAS. Dietary exposure to led lower total brain dopamine (DA) male mice, as compared control. On transcript level, tyrosine hydroxylase (th) exposed males reduced, control group. No...
In the present study, developmental and reproductive effects of lifelong exposure to environmental relevant concentrations two natural mixtures persistent organic pollutants (POP) were investigated using classical molecular methods in a controlled zebrafish model. The used extracted from burbot ( Lota lota ) liver originating freshwater systems Norway: one mixture with high levels background polybrominated diphenyl ethers (PBDE), polychlorinated biphenyls (PCB),...
Aflatoxins are fungal metabolites that contaminate foods and feeds, causing adverse health effects in humans animals. This study determined the occurrence of aflatoxins fish feeds their potential on fish. Eighty-one were sampled from 70 farms 8 feed manufacturing plants Nyeri, Kenya for aflatoxin analysis using competitive enzyme-linked immunosorbent assay. Fish 12 gross microscopic pathological examination. Eighty-four percent tested positive aflatoxins, ranging 1.8 to 39.7 µg/kg with a...
Persistent organic pollutants (POPs), including brominated flame retardants (BFRs), perfluoroalkyl substances (PFAS) and metals, can accumulate in marine mammals be transferred to offspring. In this study, we analyzed 64 lipophilic POPs, four emerging BFRs, the blubber, liver muscle of 17 adult common minke whales (Balaenoptera acutorostrata) from Barents Sea investigate occurrence tissue partitioning. addition, placental transfer concentration ratios 14 PFAS metals were quantified nine...
Abstract Little is known of the movement or presence unregulated, emerging contaminants in top predators. The aim present study was to conduct first screening legacy and multiple tissues killer whales ( Orcinus orca ) from Norway investigate tissue partitioning maternal transfer. Blubber collected 8 2015 2017, addition muscle 5 individuals, kidney, liver, heart, spleen a neonate. We screened for 4 unregulated brominated flame retardants found pentabromotoluene (PBT) hexabromobenzene (HBB) at...
The aim of this study was to assess the levels heavy metals in both wild and farmed tilapia on Lake Kariba Zambia evaluate impact intensive fish farming tilapia. Three sites for (2 distant 1 proximal farms) two farms were selected. One hundred (52 from sites; 20 near farms; 28 fish) sampled muscle tissues excised analysis (Mg, Fe, Zn, Al, Cu, Se, Co, Mo, As, Cr, V, Ni, Hg, Pb, Li, Cd, Ag) by acid (HNO3) digestion ICP-MS. All found be below maximum limits (MLs) set WHO/EU. Essential higher...