A5027752331- SARS-CoV-2 and COVID-19 Research
- Cell Adhesion Molecules Research
- Cerebrovascular and genetic disorders
- COVID-19 Clinical Research Studies
- Endometriosis Research and Treatment
- Gut microbiota and health
- SARS-CoV-2 detection and testing
- Oral microbiology and periodontitis research
- Diet and metabolism studies
- Reproductive System and Pregnancy
- RNA Interference and Gene Delivery
- Genomics, phytochemicals, and oxidative stress
- Phytochemicals and Antioxidant Activities
- Prostate Cancer Treatment and Research
- Nutrition, Genetics, and Disease
- Cancer Immunotherapy and Biomarkers
- Cancer, Lipids, and Metabolism
- Angiogenesis and VEGF in Cancer
- Curcumin's Biomedical Applications
- Renal Diseases and Glomerulopathies
- Salivary Gland Tumors Diagnosis and Treatment
- Tea Polyphenols and Effects
- Clostridium difficile and Clostridium perfringens research
- Oral Health Pathology and Treatment
- Antibiotic Resistance in Bacteria
Link Campus University
2024-2025
University of Campania "Luigi Vanvitelli"
2015-2024
Temple University
2017-2022
University of Naples Federico II
1999-2017
Emory University
2010
Mayo Clinic
2010
University of Turin
1999-2001
Ospedale Humanitas Gradenigo
2000
University of Insubria
1998
Oral pathogens may exert the ability to trigger differently activation of local macrophage immune responses, for instance Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans induce predominantly pro-inflammatory (M1-like phenotypes) while oral commensal microbiota primarily elicits functions consistent with anti-inflammatory (M2-like phenotypes).In healthy individuals vs. periodontal disease patients' blood samples, differentiation process from monocyte M1 M2 was conducted...
HIV-infected patients suffer several renal syndromes, which can progress rapidly from insufficiency to end-stage disease. Histologically, HIV-induced nephropathy is characterized by prominent tubulopathy with apoptosis of tubular cells. Clinical and experimental evidence suggests that injury may be directly related virus infection. Although HIV-1 a polytropic not solely lymphotropic pathogen, the susceptibility cells remains determined. This paper demonstrates in vitro permissiveness...
HtrA1 belongs to a family of serine proteases found in organisms ranging from bacteria humans. Bacterial (DegP) is heat shock-induced protein that behaves as chaperone at low temperature and protease high help remove unfolded proteins during shock. In contrast bacterial HtrA1, little known about the function human HtrA1. Here, we report first evidence microtubule-associated modulates microtubule stability cell motility. Intracellular localized microtubules PDZ (PSD95, Dlg, ZO1)...
Tumor immunologic microenvironment is strongly involved in tumor progression and the presence of infiltrating lymphocytes (TIL) with different phenotypes has been demonstrated to be prognostic relevance malignancies. We investigated whether TIL infiltration tissues could also predict outcome prostate cancer patients. To this end, we carried out a retrospective analysis correlating locally advanced patients undergone salvage radiotherapy upon relapse after radical surgery by populations....
Beer is one of the most consumed alcoholic beverages in world, rich chemical compounds natural origin with high nutritional and biological value. It made up water, barley malt, hops, yeast. The main nutrients are carbohydrates, amino acids, minerals, vitamins, other such as polyphenols which responsible for many health benefits associated this consumption drinks. Hops malt raw materials beer a source phenolic compounds. In fact, about 30% comes from hops 70%-80% malt. Natural foods or plants...
The coronavirus disease 2019 (COVID-19) global pandemic created an unprecedented public health emergency. Early recognition of infected person and disruption the transmission pathway are keys to controlling this major threat around world. scientifically reliable screening method is RT-PCR test that performed on ororhinopharyngeal swab in laboratory. In current severe SARS-CoV-2 pandemic, it necessary identify devices for rapid diagnosis reduce spread disease. aim study was provide a...
Renal cell carcinoma is an aggressive disease often asymptomatic and weakly chemo-radiosensitive. Currently, new biologic drugs are used among which everolimus, mTOR inhibitor, that has been approved for second-line therapy. Since involved in the control of autophagy, its antitumor capacity limited. In this view, chloroquine, a 4-alkylamino substituted quinoline family member, autophagy inhibitor blocks fusion autophagosomes lysosomes. present study, we evaluated effects everolimus alone or...
Head and neck region is involved in a high percentage of malignant lesions, oral squamous cell carcinoma (OSCC) undoubtedly the most frequently found, accounting for over 90% tumors. Hormone receptor overexpression, like Estrogen Receptor (ER), Progesterone (PR) Endothelial Growth Factor (EGFR), signaling have been related to pathogenesis OSCC. For metastasis OSCC, Cancer Stem Cells (CSCs) undergo epithelial mesenchymal transition (EMT) under influence growth factors, cytokines, regulation...
This study was conceived to evaluate the effects of three different diets on body composition, metabolic parameters, and serum oxidative status. We enrolled groups healthy men (omnivores, vegetarians, vegans) with similar age, weight BMI, we observed a significant decrease in muscle mass index lean vegan compared vegetarian omnivore groups, higher homocysteine levels vegetarians vegans omnivores. studied whether from omnivore, vegetarian, subjects affected stress, growth differentiation both...