A5070024844- Analytical Chemistry and Chromatography
- Analytical chemistry methods development
- Pharmacological Effects and Assays
- Chemical and Physical Properties in Aqueous Solutions
- Mass Spectrometry Techniques and Applications
- Pesticide Residue Analysis and Safety
- Ionic liquids properties and applications
- Electrochemical Analysis and Applications
- Phytochemistry and Biological Activities
- Pharmaceutical and Antibiotic Environmental Impacts
- Essential Oils and Antimicrobial Activity
- Forensic Toxicology and Drug Analysis
- Beetle Biology and Toxicology Studies
- Bioactive Natural Diterpenoids Research
- Coleoptera Taxonomy and Distribution
- Natural product bioactivities and synthesis
- Thermodynamic properties of mixtures
- Traditional and Medicinal Uses of Annonaceae
- Plant Toxicity and Pharmacological Properties
- Renal function and acid-base balance
- Electrochemical sensors and biosensors
- Chromatography in Natural Products
- Aquaculture Nutrition and Growth
- Milk Quality and Mastitis in Dairy Cows
- Microbial Metabolites in Food Biotechnology
Sapienza University of Rome
2015-2021
Solid-phase extraction (SPE) coupled to LC/MS/MS analysis is a valid approach for the determination of organic micropollutants (OMPs) in liquid samples. To remove greatest number OMPs from environmental matrices, development innovative sorbent materials crucial. Recently, much attention has been paid inorganic nanosystems such as graphite-derived materials. Graphene oxide employed water-purification processes, including removal several dyes, flame retardants, or pharmaceutical products....
Polymeric nanoparticle-based carriers are promising agents to deliver drugs cells. Vitisvinifera phenolic compounds known for their antifungal activity against Candida albicans. The aim of the present study was investigate pterostilbene or crude extracts from non-fermented grape pomace, entrapped in poly(lactic-co-glycolic) acid nanoparticles (NPs), with diameters 50 and 150 nm, on biofilm. fluorescent probe coumarin 6 used uptake poly(lactic-co-glycolic)acid (PLGA) NPs planktonic cells...
In the present work, dispersive liquid-liquid microextraction (DLLME) was used to extract six synthetic cannabinoids (JWH-018, JWH-019, JWH-073, JWH-200, or WIN 55,225, JWH-250, and AM-694) from oral fluids. A rapid baseline separation of analytes achieved on a bidentate octadecyl silica hydride phase (Cogent Bidentate C18; 4.6 mm × 250 mm, 4 μm) maintained at 37 °C, by eluting in isocratic conditions (water:acetonitrile (25:75, V/V)). Detection performed using positive electrospray...
The changes upon methanol (MeOH) addition in the structural arrangement of highly eco-friendly deep eutectic solvent (DES) formed by choline chloride (ChCl) and sesamol 1:3 molar ratio have been studied means attenuated total reflection Fourier transform infrared spectroscopy, small- wide-angle X-ray scattering (SWAXS), molecular dynamics simulations. introduction MeOH into DES promotes increase number Cl-MeOH hydrogen bonds (HBs) through replacement molecules from anion coordination sphere....
This paper describes, for the first time, use of oxidized buckypaper (BP) as a sorbent membrane stir-disc solid phase extraction module. The original device, consisting BP disc ( d = 34 mm) enveloped in polypropylene mesh pouch, was designed to extract organic micropollutants (OMPs) from environmental water samples dynamic mode. High-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) used analyze extracts. Several classes pesticides and pharmaceuticals were chosen model...
The structural properties of the choline chloride : sesamol 1 3 DES have been investigated by means SWAXS measurements and MD simulations.
The use of psychoactive substances is a serious problem in today's society and reliable methods analysis are necessary to confirm their occurrence biological matrices. In this work, green sample preparation technique prior HPLC-MS was successfully applied the extraction 14 illicit drugs from urine samples. isolation procedure dispersive liquid-liquid microextraction based on low transition temperature mixture (LTTM), composed choline chloride sesamol molar ratio 1:3 as extracting solvent....
Adulteration of Mozzarella di Bufala Campana with cow milk is a common fraud because the high price and limited seasonal availability water buffalo milk. To identify such adulteration, this work proposes novel approach based on use species-specific, low-molecular-weight biomarkers (LMWBs). Liquid chromatography-tandem mass spectrometry screening analyses identified β-carotene, lutein, β-cryptoxanthin as LMWBs milk, while ergocalciferol was found only in Adulterated mozzarellas were prepared...
This paper describes an analytical approach, based on LC-diode array detector-MS/MS (LC-DAD-MS/MS), for characterizing the fat-soluble micronutrient fraction in rainbow trout (Oncorhynchus mykiss). Two different procedures were applied to isolate analytes from liver and muscle tissue: overnight cold saponification hydrolyze bound forms simplify analysis; matrix solid-phase dispersion avoid artifacts maintain unaltered naturally occurring forms. Analytes separated a C30 column by using...
As it is known, the chromatographic separations of vitamins not a trivial issue. The subtle heterogeneity among homologs belonging to same group makes difficult perform their speciation. On other hand, differences in terms structure complicate simultaneous analysis main forms several vitamin groups. Long times as well use conventional toxic organic solvents, such hexane and MeOH, are downsides methods based on liquid chromatography. Over last few years, Ultra-Performance Convergence...
In this paper, the first phytochemical analysis of ethanolic extract Daphne sericea Vahl flowering aerial parts collected in Italy and its biological activities were reported. Eleven compounds identified i.e., α-linolenic acid (1), tri-linoleoyl-sn-glycerol (2), pheophorbide a ethyl ester (3), pilloin (4), sinensetin (5), yuanhuanin (6), rutamontine (7), syringin (8), p-coumaric (9), p-anisic (10) caffeic (11). To best our knowledge, (1-4, 7-8 10) isolated from D. for time during work,...
Abstract Cantharidin (CA), a toxic terpene produced by blister beetles (Coleoptera: Meloidae), attracts the interest of many researchers for its renowned medical properties. The CA content in has been mainly quantified some Oriental species, due to their use traditional Chinese medicine, or few other species toxicological importance. As quantification largely ignored members this family, we aimed at estimating natural populations two most abundant central Italy, Mylabris variabilis and Lydus...
This paper describes a rapid method for confirming residues of thyreostats in meat-based baby foods by using liquid chromatography - dual polarity electrospray tandem mass spectrometry (LC-ES(±)-MS/MS). Six thioureylenes, belonging to the group thiouracil and imidazole, were selected this work: (TU), methylthiouracil (MTU), propylthiouracil (PTU), phenylthiouracil (PhTU), mercaptobenzimidazole (MBI) tapazole (TAP). The amphoteric nature these compounds allows their detection both positive...
In this paper, the phytochemical analysis of seeds a new Iranian Plantago ovata Forssk. population exemplar is reported. This was carried out by means hydroalcoholic maceration, column chromatography, NMR and MS analyses led to isolation sixteen compounds belonging five different classes natural compounds. After comparison with previous analyses, clear difference about their whole patterns could be observed in some terms. A possible explanation generally given, too.
Thyreostats can be used fraudulently to promote a rapid increase in weight of breeding animals at low cost. Their severe toxicological effects impose the development reliable analytical methods monitoring plans. This work describes an alternative approach isolate residues thiouracil, methyl-thiouracil, propyl-thiouracil, phenyl-thiouracil, tapazole and mercaptobenzimidazole from bovine muscle tissue. The developed procedure is based on following three steps: i) matrix solid-phase dispersion...