- Metabolomics and Mass Spectrometry Studies
- Analytical Chemistry and Chromatography
- NMR spectroscopy and applications
- Advanced NMR Techniques and Applications
- Spectroscopy and Chemometric Analyses
- Nuts composition and effects
- Inorganic and Organometallic Chemistry
- Molecular spectroscopy and chirality
- Electron Spin Resonance Studies
- Phytochemicals and Antioxidant Activities
- Nuclear physics research studies
- Chemical Reaction Mechanisms
- Advanced Chemical Sensor Technologies
- Plant biochemistry and biosynthesis
- Lanthanide and Transition Metal Complexes
- Metal complexes synthesis and properties
- Fermentation and Sensory Analysis
- DNA and Nucleic Acid Chemistry
- Mass Spectrometry Techniques and Applications
- Metabolism and Genetic Disorders
- GABA and Rice Research
- Phytochemistry and Biological Activities
- Carbohydrate Chemistry and Synthesis
- Synthesis of heterocyclic compounds
- Crystal structures of chemical compounds
Sapienza University of Rome
2013-2025
University of Rome Tor Vergata
2001
Istituto di Chimica Biomolecolare
1974-1985
Istituto di Radioastronomia di Bologna
1976-1985
Utrecht University
1984
Energy Research Centre of the Netherlands
1983-1984
Antineoplastic drugs are used to treat cancer, having their therapeutic effect by inhibiting the cell division process. Although cancer cells, due rapid growth, more sensitive toxic effects of chemotherapeutic agents, healthy cells and tissues may also be damaged. Many studies show acute chronic toxicity both in patients treated with chemotherapy exposed workers. In fact, exposure these substances can linked formation different types secondary tumors. The International Agency on Research...
Breast milk is a complex fluid evolutionarily adapted to satisfy the nutritional requirements of growing infants. In addition, biochemical and immunological components protect newborns against infective agents in new environment. Human oligosaccharides, third most abundant component breast milk, are believed modulate microbiota composition, thus influencing wide range physiological processes infant. also contains number other bioactive compounds, functional role which has not yet been...
The metabolite profile of aqueous extracts two peach varieties, Percoca Romagnola 7 and Flaminia, with different susceptibilities to Ceratitis capitata attack was investigated by means 1D 2D high-field NMR spectroscopy. Water-soluble metabolites belonging classes such as organic acids (citric, fumaric, malic, quinic, shikimic, succinic acids), sugars (fucose, fructose, fructose-6-phosphate, glucose, glucose-6-phosphate, rhamnose, sucrose, xylose), amino (alanine, asparagine, isoleucine,...
An NMR analytical protocol based on complementary high and low field measurements is proposed for blueberry characterization. Untargeted metabolite profiling of blueberries aqueous organic extracts as well targeted analysis focused anthocyanins other phenols are reported. Bligh-Dyer microwave-assisted extractions were carried out compared showing a better recovery lipidic fraction in the case microwave procedure. Water-soluble metabolites belonging to different classes such sugars, amino...
Objective: The aim of this study is to evaluate the systemic effects an isotonic sports drink on metabolic status athletes Italian Olympic rowing team during recovery after strenuous and prolonged physical exercise by means nuclear magnetic resonance (NMR)-based metabolomics analysis plasma urine.Methods: Forty-four male were enrolled in a double-blind crossover study. All subjects underwent 2 evaluations at 1-week intervals. evaluation was performed ergometer produce state dehydration....
High-resolution proton NMR spectroscopy was performed on three Italian hazelnut cultivars, Tonda di Giffoni, Mortarella and Gentile Romana, it allowed to define their metabolic profile. The hazelnuts were grown in the same pedoclimatic conditions Monti Cimini (Latium) area. samples obtained by using a modified Bligh-Dyer extraction protocol which did not give rise artefacts arising from demolition of macromolecular structures such as proteins polysaccharides. Metabolites belonging different...
The metabolic profiling of aqueous extracts Zespri Gold ( Actinidia chinensis ) and CI.GI (a controlled crossbreed from different species deliciosa kiwifruits the water state outer pericarp entire fruits were monitored over season by means high-field NMR spectroscopy T(2) relaxation time measurements, respectively, compared with corresponding ones Hayward previously investigated. A more complete assignment (1)H spectrum respect to that obtained was reported: histidine, phenylalanine,...
Carrots are usually consumed in their native form or processed into many different products. Carrot juice is a popular beverage throughout the world and attracting increasing attention due to its nutritional value, being natural source of bioactive compounds. Ready-to-drink carrot juices produced same factory were analyzed by (1)H nuclear magnetic resonance (NMR) spectroscopy. The made from roots cultivar grown three geographical areas Italy. More than 30 compounds have been identified...