A5041049293- Bariatric Surgery and Outcomes
- Diet and metabolism studies
- Diabetes Treatment and Management
- Body Contouring and Surgery
- Regulation of Appetite and Obesity
- Metabolism, Diabetes, and Cancer
- COVID-19 Clinical Research Studies
- Pharmacology and Obesity Treatment
- Nutrition, Genetics, and Disease
- Nutritional Studies and Diet
- Liver Disease Diagnosis and Treatment
- Cardiovascular Disease and Adiposity
- Esophageal and GI Pathology
- Eating Disorders and Behaviors
- SARS-CoV-2 and COVID-19 Research
- Obesity and Health Practices
- Adipokines, Inflammation, and Metabolic Diseases
- Long-Term Effects of COVID-19
- Food Allergy and Anaphylaxis Research
- Gestational Diabetes Research and Management
- Adipose Tissue and Metabolism
- Pancreatitis Pathology and Treatment
- Consumer Attitudes and Food Labeling
- Lymphatic System and Diseases
- Growth Hormone and Insulin-like Growth Factors
Agostino Gemelli University Polyclinic
2020-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2024
Università Cattolica del Sacro Cuore
2013-2023
Agenzia per la Promozione All'estero e l'Internazionalizzazione Delle Imprese Italiane
2018
University of the Sacred Heart
2014
Catholic University of America
2008-2011
Sapienza University of Rome
2006-2010
Roux-en-Y gastric bypass and biliopancreatic diversion can markedly ameliorate diabetes in morbidly obese patients, often resulting disease remission. Prospective, randomized trials comparing these procedures with medical therapy for the treatment of are needed.In this single-center, nonblinded, randomized, controlled trial, 60 patients between ages 30 years a body-mass index (BMI, weight kilograms divided by square height meters) 35 or more, history at least 5 diabetes, glycated hemoglobin...
Currently, there are no data in the literature regarding pathophysiological mechanisms involved rapid resolution of type 2 diabetes after bariatric surgery, which was reported as an additional benefit surgical treatment for morbid obesity. With this question mind, insulin sensitivity, using euglycemic-hyperinsulinemic clamp, and secretion, by C-peptide deconvolution method oral glucose load, together with circulating levels intestinal incretins adipocytokines, have been studied 10 diabetic...
Mingrone, Geltrude; Panunzi, Simona; De Gaetano, Andrea; Guidone, Caterina; Iaconelli, Amerigo; Leccesi, Laura; Nanni, Giuseppe; Pomp, Alfons; Castagneto, Marco; Ghirlanda, Giovanni; Rubino, Francesco Author Information
OBJECTIVE—The purpose of this study was to clarify the effects maternal obesity on insulin sensitivity and secretion in offspring. RESEARCH DESIGN AND METHODS—Fifty-one offspring both sexes obese (Ob group) 15 normal-weight (control mothers were studied. Plasma glucose, insulin, C-peptide measured during an oral glucose tolerance test (OGTT). Insulin calculated using index, β-cell computed by a mathematical model. Fasting leptin adiponectin also measured. Body composition assessed dual-X-ray...
The surgical option could represent a valid alternative to medical therapy in some diabetic patients. However, no data are available on long-term effects of metabolic surgery complications. We aimed determine whether patients with newly diagnosed type 2 diabetes who underwent bilio-pancreatic diversion (BPD) had less micro- and macrovascular complications than those received conventional therapy.This was an unblinded, case-controlled trial 10-years' follow-up, conducted from July 1998...
Interleukin-6 signal blockade showed preliminary beneficial effects in treating inflammatory response against SARS-CoV-2 leading to severe respiratory distress. Herein we describe the outcomes of off-label intravenous use Sarilumab SARS-CoV-2-related pneumonia.53 patients with pneumonia received Sarilumab; pulmonary function improvement or Intensive Care Unit (ICU) admission rate medical wards, live discharge ICU treated and safety profile were recorded. 400 mg was administered intravenously...
Introduction: Single Anastomosis Duodenal-Ileal Bypass with Sleeve Gastrectomy (SADI-S), like other hypoabsorptive procedures, could be burdened by long-term nutritional deficiencies such as malnutrition, anemia, hypocalcemia, and hyperparathyroidism. Objectives: We aimed to report our experience in terms of mid-term (2 years) bariatric, nutritional, metabolic results patients who underwent SADI-S both a primary or revisional procedure. Methods: One hundred twenty-one were scheduled for...
OBJECTIVE Bariatric surgery has been shown to have important long-term metabolic effects resulting in enhanced insulin sensitivity and improved glucose tolerance patients with type 2 diabetes. The contribution of reduced caloric intake these beneficial remains unclear. aim this study was compare the short-term (1 week) bariatric surgical procedures a very low (VLCI) on (IS) secretion (ISR) nondiabetic obese subjects. RESEARCH DESIGN AND METHODS Twenty without diabetes (BMI 44.2 ± 0.7 kg/m2)...
Both weight regain and dumping syndrome (DS) after Roux-en-Y gastric bypass (RYGB) have been related to the dilation of gastro-jejunal anastomosis. The aim this study is assess safety long-term efficacy endoscopic transoral outlet reduction (TORe) for DS and/or RYBG.A retrospective analysis was performed on a prospective database. Sigstad's score, early late Arts Dumping Score (ADS) questionnaires, absolute loss (AWL), percentage total body (%TBWL), excess (%EWL) were assessed at baseline 6,...
To assess the effect of Roux-en-Y gastric bypass (RYGB) on high-density lipoprotein cholesterol (HDL-C) concentration and its apolipoprotein A4 (ApoA4) content at 1 year after bariatric surgery in comparison with a hypocaloric diet. Secondary aim was to measure total triglycerides levels insulin sensitivity interventions.Very few prospective uncontrolled studies have investigated effects RYGB cardiovascular risk factors. No controlled had as primary goal changes HDL-C bypass.Forty subjects...