A5040546928- Sarcoma Diagnosis and Treatment
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Lymphoma Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Lung Cancer Treatments and Mutations
- Glioma Diagnosis and Treatment
- Effects of Radiation Exposure
- Medical Imaging and Pathology Studies
- Respiratory Support and Mechanisms
- SARS-CoV-2 and COVID-19 Research
- Asthma and respiratory diseases
- Intensive Care Unit Cognitive Disorders
- Cancer Treatment and Pharmacology
- Advanced Radiotherapy Techniques
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Hematopoietic Stem Cell Transplantation
- Ultrasound in Clinical Applications
- Soft tissue tumor case studies
- COVID-19 and healthcare impacts
- Cardiac tumors and thrombi
- Cancer Diagnosis and Treatment
- Telemedicine and Telehealth Implementation
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neurosurgical Procedures and Complications
Agostino Gemelli University Polyclinic
2020-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2010-2024
Policlinico San Matteo Fondazione
2010-2024
Pulmonary Associates
2024
Università Cattolica del Sacro Cuore
2017-2023
IRCCS Policlinico San Donato
2020
Santa Maria Nuova Hospital
2016
Fondazione IRCCS Istituto Nazionale dei Tumori
1981-2001
Tumori Foundation
1982-1991
COVID-19 is a respiratory infectious disease that can cause respiratory, physical and psychological long-term dysfunctions in patients. First recommendations on management were published, but they not based the specific needs due to COVID-19. In this paper we share early experiences from clinical field Northern Italy, where epidemic started February. This summarizes second webinar (230 live attendees, 11,600 viewers of recorded version) organized by Italian Society Physical Rehabilitation...
Interleukin-6 signal blockade showed preliminary beneficial effects in treating inflammatory response against SARS-CoV-2 leading to severe respiratory distress. Herein we describe the outcomes of off-label intravenous use Sarilumab SARS-CoV-2-related pneumonia.53 patients with pneumonia received Sarilumab; pulmonary function improvement or Intensive Care Unit (ICU) admission rate medical wards, live discharge ICU treated and safety profile were recorded. 400 mg was administered intravenously...
PURPOSE A single-center, prospective, nonrandomized trial was conducted to evaluate therapeutic results of a short-term program chemotherapy followed by locoregional radiotherapy in stage I or II intermediate/aggressive non-Hodgkin's lymphoma (NHL). PATIENTS AND METHODS From 1985 1990, 183 consecutive patients with diagnosis NHL (Working Formulation [WF] E through J excluding Burkitt's type), Ann Arbor II, and no more than three sites disease involvement were treated four cycles...
PURPOSE To assess the toxicity, efficacy, and applicability of high-dose therapy with bone marrow and/or peripheral-blood autotransplantation in high-risk, previously untreated patients multiple myeloma. PATIENTS AND METHODS Thirteen consecutive high-labeling index (LI) myeloma received a novel sequential (HDS) regimen consisting administration cyclophosphamide (7 g/m2) followed by vincristine (1.4 mg/m2) plus methotrexate (8 g/m2 leucovorin rescue), etoposide (2 and, finally, total-body...
The novel coronavirus SARS-Cov-2 can infect the respiratory tract causing a spectrum of disease varying from mild to fatal pneumonia, and known as COVID-19. Ongoing clinical research is assessing potential for long-term sequelae in these patients. We assessed function cohort patients after recovering infection, stratified according PaO2/FiO2 (p/F) values.Approximately one month hospital discharge, 86 COVID-19 underwent physical examination, arterial blood gas (ABG) analysis, pulmonary tests...
Twelve children younger than 16 years affected by undifferentiated nasopharyngeal carcinoma (NPC) with advanced primary tumor (T3, T4) were treated chemotherapy consisting of Adriamycin (ADM [doxorubicin; Adria Laboratories, Columbus, OH]), vincristine (VCR), and cyclophosphamide (CYC), radiotherapy. Preradiation produced partial responses in eight ten evaluable patients. Eleven 12 patients achieved a complete response following The actuarial 3-year continuous relapse-free survival (CRFS)...
PURPOSE This study assessed the efficacy of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) or granulocyte (rhG-CSF) in ameliorating extent and duration hematologic toxicity after high-dose etoposide cancer therapy. PATIENTS AND METHODS Thirty-two non-Hodgkin's lymphoma myeloma patients were treated with 2 to 2.4 g/m2 infused intravenously (IV) during a 10- 12-hour period, followed 72 hours later by subcutaneous administration rhGM-CSF rhG-CSF. Hematologic was...
Background/Objectives: Benralizumab is a monoclonal antibody that targets the interleukin-5 receptor (IL-5Rα), leading to rapid depletion of blood eosinophils. RCTs have demonstrated efficacy in patients with severe eosinophilic asthma (SEA). The aim this study was assess benralizumab on sinonasal outcomes real-life setting SEA and concomitant chronic rhinosinusitis nasal polyps (CRSwNP). Methods: We included 25 (mean age: 57.47 years, range: 35–77, F/M = 12:13) who were prescribed 30 mg...
Abstract Background Neurological manifestations of Sars-CoV-2 infection have been described since March 2020 and include both central peripheral nervous system manifestations. symptoms, such as headache or persistent loss smell taste, also documented in COVID-19 long-haulers. Moreover, long lasting fatigue, mild cognitive impairment sleep disorders appear to be frequent term neurological after hospitalization due COVID-19. Less is known relation nerve injury related infection. Case...
A series of 15 consecutive children with head and neck nonorbital rhabdomyosarcoma (RMSA) meningeal extension were prospectively treated chemotherapy consisting Adriamycin (doxorubicin; Adria Laboratory, Columbus, OH) (ADM), vincristine (VCR), cyclophosphamide (CPM), dactinomycin (DACT) followed by radiotherapy (60 Gy) to the primary tumor volume, along intrathecal methotrexate (IT MTX). Thirteen responded preradiation chemotherapy. Four 13 relapsed. Relapse occurred at level in three four....
Purpose The aim of the study is to report our first impressions about Adherus, a novel dural sealant, used in neurosurgical endoscopic transnasal procedures. Methods We retrospectively reviewed clinical and surgical records 11 patients with intraoperative high-flow cerebrospinal fluid leak treated aid Adherus at center between February October 2014. healing level plasty was monitored evaluated radiologically regular inspections. Results With median follow-up 210 days, no postoperative CSF or...