Giovanni Di Cintio
A5082343940- Head and Neck Cancer Studies
- Long-Term Effects of COVID-19
- Nasal Surgery and Airway Studies
- Reconstructive Surgery and Microvascular Techniques
- Reconstructive Facial Surgery Techniques
- Vitamin C and Antioxidants Research
- Salivary Gland Disorders and Functions
- Cancer Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
- Tumors and Oncological Cases
- Olfactory and Sensory Function Studies
- Head and Neck Surgical Oncology
- Advanced Proteomics Techniques and Applications
- Sinusitis and nasal conditions
- Bone health and treatments
- Extracellular vesicles in disease
- Respiratory and Cough-Related Research
- Chemokine receptors and signaling
- Diverse Music Education Insights
- Ear Surgery and Otitis Media
- Trauma Management and Diagnosis
- Tracheal and airway disorders
- Nonmelanoma Skin Cancer Studies
- Vascular Tumors and Angiosarcomas
- Temporomandibular Joint Disorders
Ospedale degli Infermi
2024
Corvid Technologies (United States)
2023
Agostino Gemelli University Polyclinic
2017-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2022
Ospedale degli Infermi
2022
Università Cattolica del Sacro Cuore
2018-2021
Nutritional status is a critical factor throughout COVID-19 disease course. Malnutrition associated with poor outcomes in hospitalized patients.
Abstract Objectives The primary end point of this study was to evaluate the impact bile acids on severity laryngo‐pharyngeal reflux (LPR) and possible correlation with esophagitis upper airway malignancies. second if salivary molecules other than pepsin might serve as diagnostic biomarkers LPR. Design Observational prospective comparative study. Setting Otorhinolaryngology unit a tertiary hospital. Participants Sixty‐two consecutive adult outpatients suspected Main outcome measures Bile...
The novel coronavirus SARS-Cov-2 can infect the respiratory tract causing a spectrum of disease varying from mild to fatal pneumonia, and known as COVID-19. Ongoing clinical research is assessing potential for long-term sequelae in these patients. We assessed function cohort patients after recovering infection, stratified according PaO2/FiO2 (p/F) values.Approximately one month hospital discharge, 86 COVID-19 underwent physical examination, arterial blood gas (ABG) analysis, pulmonary tests...
Purpose Surgery, external beam radiotherapy (EBRT), and interventional (IRT, BrachyTherapy BT) are the current therapeutic options for nose vestibule (NV) squamous cell carcinoma (SCC). In this article, we evaluate functional parameters of patients affected by SCCs NV, primarily treated interstitial IRT comparing them with healthy controls intensity-modulated EBRT. Methods Ten using (group 1), 10 eight EBRT 2) on region were submitted to clinical evaluation (with NOSE scale score),...
Altered immune responses have been reported in head and neck cancer, some of these associated with poor clinicaloutcomes. A multiple-array technology platform was used to simultaneously evaluate the levels 25 cytokines. Pre-treatment serum levelswere evaluated 31 HNSCC patients 6 healthy controls. The 8 cytokines, specifically IL-1ra, IL-2, IL-5, IL-6, IL-8, IL-17, IFN-γand IP-10, were significantly higher than Among cancer we observed lower IFN-g IL-7 caseswith nodal metastases compared...
Abstract Background Salvage total laryngectomy (TL) and laryngopharyngectomy (LP) after chemoradiotherapy may produce disfiguring defects with severe complications that require complex reconstructions. Methods Between January 2012 December 2018, we enrolled 25 patients who underwent internal mammary artery perforator (IMAP) flap reconstruction salvage TL or LP. We performed retrospective review of clinical charts to collect information such as history, timing reconstruction, type defect,...
Objective. Polidocanol sclerotherapy of head and neck venous malformations (VMs) lymphatic (LMs) has been reported only in limited series. In this manuscript we evaluated the efficacy safety polidocanol a series malformations. Methods. This retrospective observational study analysed data on 20 VMs LMs that underwent to percutaneous or endoscopic intra-lesional 3% microfoam at our institution. Clinical response was ranked as excellent, moderate poor based volume reduction by MRI resolution...
Abstract Background Neurological manifestations of Sars-CoV-2 infection have been described since March 2020 and include both central peripheral nervous system manifestations. symptoms, such as headache or persistent loss smell taste, also documented in COVID-19 long-haulers. Moreover, long lasting fatigue, mild cognitive impairment sleep disorders appear to be frequent term neurological after hospitalization due COVID-19. Less is known relation nerve injury related infection. Case...
Ophthalmic vein thrombosis is a severe clinical entity with proptosis, eyelid swelling, orbital pain and reduction of visual acuity; its incidence rare 3-4 cases /million /year. Clinical manifestations result from venous congestion caused by septic (orbital cellulitis) or aseptic aetiologies (coagulopathies, trauma) in some it could be associated cavernous sinus thrombosis. In this paper, we describe case report unique the literature, bilateral ophthalmic veins due to both causes...
Objectives/Hypothesis To analyze stapler benefits in salvage total laryngectomy terms of surgical time, hospitalization length, oral feeding and occurrence pharyngocutaneous fistula, to evaluate risk factors for its onset. Study Design Retrospective analysis. Methods One hundred fourteen patients affected by endolaryngeal squamous cell carcinoma who underwent following primary treatment failure were reviewed. We divided into two groups based on type pharyngeal suture performed: mechanical...
The aim of this study was to assess if a correlation exists between language learning skills and musical aptitude through the analysis ofscholarly outcomes concerning foreign languages music. We enrolled 502 students from secondary Italian school (10-14 years old), attending both traditional courses (2 hours/week music classes scheduled) special (six hours). For statisticalanalysis, we considered grades in English, French Music. Our results showed significant two foreignlanguages music,...
Abstract Background Compared to the other members of human epidermal growth factor family receptors (HER), role HER3 has not been well defined in laryngeal cancer. The predictive and prognostic focus clinical attention but research findings are contradictory, especially squamous cell carcinoma (LSCC). variable localization within cancer cells primary acquired resistance HER1-targeted therapies remain unclear. Methods We performed a retrospective analysis two cohorts 66 homogeneous...
The primary aim of this study was to illustrate the prevalence facial skeletal discrepancy in an Italian sample. Another toevaluate effectiveness sagittal classification order establish a morphologic pattern growth useful fordiagnosis and prediction therapeutic results. authors considered sample 732 patients (426 females 306 males) aged between6 17 years old. Cephalometric parameters were evaluated relationship between andthe rotations (Lavergne Petrovic). Facial types with neutral...
BACKGROUND The columella has many fundamental functions, such as nasal breathing and support of the tip, in addition to aesthetic role it plays. is one most difficult subunits, both from point view disease control that reconstruction. Lesions involving can be control, malignancies spread septum, subcutaneous tissues lip, floor cavities. Many reconstruction methods after resection have been proposed (local flaps, skin grafts, regional free flaps), depending on size defect, patient's features,...
The role of elective neck dissection during salvage surgery in patients with a clinically negative (cN0) is still discussed. main objective this work was to estimate the prevalence and predictive factors occult nodes metastasis; we therefore aimed evaluate survival rate oncologic outcomes cN0 who underwent total laryngectomy bilateral dissection. In retrospective observational study, enrolled 80 affected by recurrent laryngeal cancer selective Several parameters were collected order find...
Parathyroid hormone-related peptide (PTHrP) overexpression and poor patient outcome have been reported for many human tumors, but no studies are available in laryngeal cancer. Therefore, we studied the expression of PTHrP its receptor, parathyroid receptor type 1 (PTH1R), primary locally advanced squamous cell carcinomas (LALSCC) also relation to clinical patients.We conducted a retrospective exploratory study, using immunohistochemistry, on PTHrP, PTH1R HER1 expressions LALSCC 66 patients...
Non-melanoma Skin cancer, including cutaneous squamous cell carcinoma and basal carcinoma, is the most common form of malignancy in Caucasian population, skin head neck site involved. They should not be underestimated; particular, high-risk lesions advanced cancers require accurate diagnostic work up, aggressive surgical treatment managed by surgeon, dermatologist plastic surgeon. Cutaneous head-neck malignancies are often overlooked or routinely treated with a multidisciplinary approach....
ResultsFor all three patients the application was well tolerated and could be performed in an ambulant setting.A reproducible dose gradient achieved patients.The surface on target side 204±19% of normalized 5 mm (100%) tissue depth 143±8% 2 64±3% 10 mm.The contra-lateral 20±8%.After radiochemotherapy with 50 Gy external beam radiotherapy concomitant chemotherapy capecitabine, a HDR brachytherapy boost 2-3 fractions 7-10 each delivered.All clinical complete response at 3 months no major...