A5023419515- Long-Term Effects of COVID-19
- Microscopic Colitis
- Helicobacter pylori-related gastroenterology studies
- Peripheral Neuropathies and Disorders
- Digestive system and related health
- Nutrition and Health in Aging
- Celiac Disease Research and Management
- Venous Thromboembolism Diagnosis and Management
- COVID-19 Clinical Research Studies
- Endometriosis Research and Treatment
- Peripheral Artery Disease Management
- Hereditary Neurological Disorders
- Systemic Sclerosis and Related Diseases
- Diet, Metabolism, and Disease
- Gastrointestinal motility and disorders
- Diet and metabolism studies
- Breast Lesions and Carcinomas
- Myasthenia Gravis and Thymoma
- Breast Cancer Treatment Studies
- Gut microbiota and health
- Advanced Radiotherapy Techniques
- Cerebrovascular and Carotid Artery Diseases
- Vitamin C and Antioxidants Research
- Diagnosis and Treatment of Venous Diseases
- Radiopharmaceutical Chemistry and Applications
Agostino Gemelli University Polyclinic
2014-2025
Università Campus Bio-Medico
2025
Università Cattolica del Sacro Cuore
2010-2024
Jeroen Bosch Ziekenhuis
2023
Corvid Technologies (United States)
2023
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2022
Cardiovascular Research Center
2022
Sapienza University of Rome
2013-2020
University of Padua
2019
Azienda Ospedaliera S.Giuseppe Moscati
2019
Long COVID, a condition characterized by symptom and/or sign persistence following an acute COVID-19 episode, is associated with reduced physical performance and endothelial dysfunction. Supplementation of l-arginine may improve muscle function stimulating nitric oxide synthesis. A single-blind randomized, placebo-controlled trial was conducted in adults aged between 20 60 years persistent fatigue attending post-acute outpatient clinic. Participants were randomized 1:1 to receive twice-daily...
Psychoactive drugs represent a major contributor to falls in older people. This study aims evaluate the prescribing practice of psychoactive people hospitalized for hip fracture (HF) and explore independent correlates deprescribing. Multicenter prospective observational including patients with HF admitted 13 Orthogeriatric wards Italian Group Orthogeriatrics (July 2019-August 2022). Patients underwent comprehensive geriatric assessment. The use associated higher risk was assessed using...
<i>Background/Aims:</i> Lactobacilli are used in the prevention and treatment of several diseases, but they also known to play a role pathogenesis dental caries. The aim our study was evaluate whether oral administration lactobacilli could change salivary counts these bacteria compared with placebo. Moreover, were administered liquid capsule form determine direct contact cavity. <i>Methods:</i> Thirty-five healthy volunteers randomized into three groups receive and/or...
Left ventricular dilatation and a low ejection fraction after acute myocardial infarction are independent indicators of poor prognosis. ACE inhibitors have been shown to decrease left infarction. In the GISSI-3 trial, patients were randomlyassigned, within 24 h onset symptoms, 6 weeks treatment with lisinopril, nitroglycerin, both or neither, in an open, 2 × factorial design. The study showed that early relatively unselected lisinopril decreases mortality at severe dysfunction. We assessed...
Non-steroidal anti-inflammatory drugs cause enterocyte damage inducing an increase of intestinal permeability. Tight junctions are the key structures in permeability mucosa. ZO-1 is a tight junction associated protein considered good marker their integrity. It has been suggested that probiotics could play protective role barrier function. We determined, vitro, whether heat-killed Lactobacillus acidophilus strain LB (LaLB) with its spent culture supernatant protects HT-29 cells from aspirin...
Non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious gastrointestinal side effects. Faecal calprotectin assay represents a simple and practical method for diagnosis of NSAID enteropathy. Intestinal micro-organisms are necessary the development NSAID-induced small bowel lesions hence it has been suggested that probiotics could protect against enteropathy.To evaluate effect probiotic mixture in comparison with placebo on faecal concentrations (FCCs) healthy volunteers receiving...
Background: Endothelial dysfunction has a role in acute COVID-19, contributing to systemic inflammatory syndrome, respiratory distress and vascular events. Evidence regarding COVID-19 middle- long-term consequences on endothelium are still lacking. Our study aimed evaluate if severity could significantly affect the endothelial function after three months from phase. Methods: We assessed outpatients with previous negative SARS-CoV-2 molecular test by measuring flow-mediated dilation (FMD)...
In a recent clinical trial, beetroot juice supplementation for 14 days yielded positive effects on systemic inflammation in adults with long COVID. Here, we explored the relationship between circulating markers of mitochondrial quality and COVID as well impact administration those markers. We conducted secondary analyses placebo-controlled randomized trial testing remedy against Analyses were 25 participants, 10 assigned to placebo (mean age: 40.2 ± 11.5 years, 60% women) 15 allocated 38.3...
Chronic venous disease (CVD) involves complex pathophysiological processes where the imbalance between matrix metalloproteinases (MMPs) and tissue inhibitors of (TIMPs) contributes to remodelling varicosities. Elevated levels MMP-2 MMP-9 are notably observed in tissues affected by ulcers. Local inflammation is a key feature CVD, with increased concentrations pro-inflammatory markers varicose veins compared healthy veins. Syndecans, components endothelial glycocalyx, play critical roles...
Atherosclerosis is a chronic and degenerative disease developing typically in the elderly; nonetheless, condition of accelerated atherosclerosis can be observed precociously presence some diseases. Endometriosis, benign gynecological disorder, shows characteristics, such as oxidative stress, systemic inflammation pro-atherogenic lipid profile, which could increase risk atherosclerosis. The aim our study was to evaluate markers subclinical young European women with endometriosis.This...
The novel coronavirus SARS-Cov-2 can infect the respiratory tract causing a spectrum of disease varying from mild to fatal pneumonia, and known as COVID-19. Ongoing clinical research is assessing potential for long-term sequelae in these patients. We assessed function cohort patients after recovering infection, stratified according PaO2/FiO2 (p/F) values.Approximately one month hospital discharge, 86 COVID-19 underwent physical examination, arterial blood gas (ABG) analysis, pulmonary tests...
Summary Background Despite the reported tolerance to a low dose of lactose, many lactose malabsorbers follow rigorous lactose‐free diet also avoiding lactose‐containing drugs. Up now, only few case reports have described onset gastrointestinal symptoms in following ingestion these It has been suggested that capsules/tablets contain no more than 400 mg lactose. Aim To evaluate breath H 2 excretion and intolerance after capsule containing or placebo through randomized, cross‐over,...