A5079533889- Systemic Lupus Erythematosus Research
- Systemic Sclerosis and Related Diseases
- Rheumatoid Arthritis Research and Therapies
- Monoclonal and Polyclonal Antibodies Research
- Diabetes and associated disorders
- Long-Term Effects of COVID-19
- Salivary Gland Disorders and Functions
- Glaucoma and retinal disorders
- Mosquito-borne diseases and control
- Peripheral Neuropathies and Disorders
- COVID-19 Clinical Research Studies
- Chronic Lymphocytic Leukemia Research
- Lymphoma Diagnosis and Treatment
- Celiac Disease Research and Management
- Immunodeficiency and Autoimmune Disorders
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Corneal surgery and disorders
- Atherosclerosis and Cardiovascular Diseases
- Inflammasome and immune disorders
- Cervical Cancer and HPV Research
- Immune Response and Inflammation
- Respiratory Support and Mechanisms
- Health and Lifestyle Studies
- Autoimmune and Inflammatory Disorders Research
- Global Cancer Incidence and Screening
Universidad del Rosario
2015-2024
We have focused on the epidemiology and immunobiology of Zika virus (ZIKV) infection factors associated with development Guillain-Barré syndrome (GBS) other neurological syndromes in Cúcuta, capital North Santander department, Colombia. Data patients ZIKV disease reported to national population-based surveillance system were used calculate basic reproduction number (R0) attack rates (ARs) as well develop epidemiological maps. Patients contacted their diagnoses confirmed. A case-control study...
Evidence supports the existence of different subphenotypes in systemic lupus erythematosus (SLE) and pivotal role cytokines autoantibodies, which interact a highly complex network. Thus, understanding how these nonlinear processes are connected observed real-life settings is major challenge. Cluster approaches may assist identification subphenotypes, represent such phenomenon, contribute to development personalized medicine. Therefore, relationship between autoantibody cytokine clusters SLE...
Autoimmune diseases (ADs) are a chronic and clinically heterogeneous group of characterized by share common immunopathogenic mechanisms risk factors (i.e., the autoimmune tautology), which explain fact that one AD may coexist with others polyautoimmunity - PolyA). In present exploratory study, mixed-cluster analysis most rheumatic (ARDs) was done. A total 187 consecutive women established systemic lupus erythematosus (n = 70), rheumatoid arthritis 51), sclerosis 35) Sjögren's syndrome 31)...
Summary Objectives To determine the prevalence and predictive factors of autoimmune hypothyroidism ( AH ) within a systemic lupus erythematosus SLE cohort to analyse current information concerning impact thyroid disease AITD autoimmunity in patients with . Methods A total 376 were assessed for presence following: (i) confirmed , (ii) positive thy‐roperoxidase/thyroglobulin antibodies [ TPOA b/TgAb] without hypothyroidism, (iii) nonautoimmune (iv) neither. Multivariate analysis classification...
Objectives To examine the prevalence and associated factors related to coexistence of antiphospholipid syndrome (APS) systemic lupus erythematosus (SLE) in a cohort Colombian patients with SLE, discuss APS other autoimmune diseases (ADs). Method A total 376 SLE were assessed for presence following: 1) confirmed APS; 2) positivity (aPL) antibodies without prior thromboembolic nor obstetric event; 3) aPL antibodies. Comparisons between groups 1 3 evaluated by bivariate multivariate analysis....
To describe ocular surface characteristics and tests' results in a healthy pediatric population.We performed cross-sectional study with 60 children, obtaining consent, OSDI screen use survey conducting tests. Statistical univariate analysis for categorical quantitative variables was made. the correlation of both eyes, we used model random effects. characterize possible profiles device use, applied mixed-cluster methodology.Sixty children between 7 17 years old were evaluated. Girl's...
Abstract Background There are few data on the clinical outcomes of patients with coronavirus disease 2019 (COVID-19) in cities over 1000 m above sea level (masl). Objectives To describe characteristics and mortality COVID-19 treated at a high complexity hospital Bogotá, Colombia, 2640 masl. Methods This was an observational study cohort including 5161 confirmed infection from 19 March 2020 to 30 April 2021. Demographic data, laboratory values, comorbidities, oxygenation indices, were...
The interest on autoimmune diseases (ADs) and their outcome at the intensive care unit (ICU) has increased due to clinical challenge for diagnosis management as well prognosis. current work presents a-year experience these topics in a tertiary hospital.The mixed-cluster methodology based multivariate descriptive methods such principal component analysis multiple correspondence analyses was performed summarize sets of related variables with strong associations common context.Fifty adult...
In Colombia and worldwide, breast cancer (BC) is the most frequently diagnosed neoplasia leading cause of death from among women. Studies predominantly involve hereditary familial cases, demonstrating a gap in literature regarding identification germline mutations unselected patients Latin-America. Identification pathogenic/likely pathogenic (P/LP) variants important for shaping national genetic analysis policies, counseling, early detection strategies. The present study included 400 women...
Background and purpose Zika virus ( ZIKV ) infection has been associated with an increased incidence of Guillain−Barré syndrome GBS but the relative frequency acute inflammatory demyelinating polyradiculoneuropathy AIDP axonal subtypes is controversial. Methods Twenty patients diagnosed according to Brighton criteria during outbreak in Cúcuta, Colombia, were evaluated clinically electrophysiologically. The electrodiagnosis was made a recently described set that demonstrated high diagnostic...
Measurement of the optic nerve sheath diameter (ONSD) provides a rapid, safe, and easy method for detecting increased intracranial pressure (ICP). However, normal mean upper limit values may vary according to sex, age, ethnicity, ultrasound technique.We aimed obtain ONSD in healthy Colombian adult population correlate it with demographic anthropometric measures.In prospective study using 10-13 MHz linear probe, eye transverse (ETD) (ONSD-TP) sagittal planes (ONSD-SP) were measured volunteers...