A5056507501- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Systemic Lupus Erythematosus Research
- Mosquito-borne diseases and control
- Peripheral Neuropathies and Disorders
- Diabetes and associated disorders
- T-cell and B-cell Immunology
- Monoclonal and Polyclonal Antibodies Research
- Immune Cell Function and Interaction
- COVID-19 and healthcare impacts
- COVID-19 and Mental Health
- Systemic Sclerosis and Related Diseases
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Salivary Gland Disorders and Functions
- Thyroid Disorders and Treatments
- Viral Infections and Vectors
- Atherosclerosis and Cardiovascular Diseases
- Cell Image Analysis Techniques
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Vector-borne infectious diseases
- Chronic Lymphocytic Leukemia Research
- Immunotherapy and Immune Responses
- Inflammasome and immune disorders
- Cardiac, Anesthesia and Surgical Outcomes
Universidad del Rosario
2016-2025
Charité - Universitätsmedizin Berlin
2022
NIHR Birmingham Biomedical Research Centre
2021
University of Birmingham
2021
Yorkshire Cancer Research
2021
Urology Foundation
2021
Association for Cancer Surgery
2021
Centro de Investigaciones Biológicas Margarita Salas
2016-2018
Consejo Superior de Investigaciones Científicas
2014
Fundación Instituto de Inmunología de Colombia
2008
Abstract Background The immunopathological pathways enabling post-coronavirus disease 2019 (COVID-19) syndrome (PCS) development are not entirely known. We underwent a longitudinal analysis of patients with COVID-19 who developed PCS aiming to evaluate the autoimmune and immunological status associated this condition. Methods Thirty-three were included for clinical autoantibody analyses, 12 whom assessed cytokines lymphocyte populations. Patients followed 7–11 months after acute COVID-19....
Convalescent plasma (CP) has emerged as a treatment for COVID-19. However, the composition and mechanism of action are not fully known. Therefore, we undertook two-phase controlled study in which, first immunological metabolomic status recovered severe patients were evaluated. Secondly, 28-day effect CP on immune response was assessed. Nineteen COVID-19 patients, 18 hospitalized with disease, 16 pre-pandemic controls included. Patients disease treated transfusion standard therapy (i.e.,...
Autoimmune responses mediated by autoantibodies have been observed in SARS-CoV-2 infection. Herein, we evaluate the presence of rheumatic, thyroid and phospholipid sera samples from 120 adult hospitalized patients with COVID-19 comparison to pre-pandemic 100 healthy individuals. In addition, estimate frequency these COVID-19, a meta-analysis selected articles was conducted. Hospitalized had latent autoimmunity characterized high anti-thyroid peroxidase antibodies, rheumatoid factor (RF),...
We have focused on the epidemiology and immunobiology of Zika virus (ZIKV) infection factors associated with development Guillain-Barré syndrome (GBS) other neurological syndromes in Cúcuta, capital North Santander department, Colombia. Data patients ZIKV disease reported to national population-based surveillance system were used calculate basic reproduction number (R0) attack rates (ARs) as well develop epidemiological maps. Patients contacted their diagnoses confirmed. A case-control study...
Evidence supports the existence of different subphenotypes in systemic lupus erythematosus (SLE) and pivotal role cytokines autoantibodies, which interact a highly complex network. Thus, understanding how these nonlinear processes are connected observed real-life settings is major challenge. Cluster approaches may assist identification subphenotypes, represent such phenomenon, contribute to development personalized medicine. Therefore, relationship between autoantibody cytokine clusters SLE...
Autoimmune diseases (ADs) are a chronic and clinically heterogeneous group of characterized by share common immunopathogenic mechanisms risk factors (i.e., the autoimmune tautology), which explain fact that one AD may coexist with others polyautoimmunity - PolyA). In present exploratory study, mixed-cluster analysis most rheumatic (ARDs) was done. A total 187 consecutive women established systemic lupus erythematosus (n = 70), rheumatoid arthritis 51), sclerosis 35) Sjögren's syndrome 31)...
Summary Objectives To determine the prevalence and predictive factors of autoimmune hypothyroidism ( AH ) within a systemic lupus erythematosus SLE cohort to analyse current information concerning impact thyroid disease AITD autoimmunity in patients with . Methods A total 376 were assessed for presence following: (i) confirmed , (ii) positive thy‐roperoxidase/thyroglobulin antibodies [ TPOA b/TgAb] without hypothyroidism, (iii) nonautoimmune (iv) neither. Multivariate analysis classification...
Objectives To examine the prevalence and associated factors related to coexistence of antiphospholipid syndrome (APS) systemic lupus erythematosus (SLE) in a cohort Colombian patients with SLE, discuss APS other autoimmune diseases (ADs). Method A total 376 SLE were assessed for presence following: 1) confirmed APS; 2) positivity (aPL) antibodies without prior thromboembolic nor obstetric event; 3) aPL antibodies. Comparisons between groups 1 3 evaluated by bivariate multivariate analysis....
Abstract The existence of a variety symptoms with duration beyond the acute phase COVID-19, is referred to as post-COVID syndrome (PCS). We aimed report series patients PCS attending Post-COVID Unit and offer comprehensive review on topic. Adult previously confirmed SARS-CoV-2 infection were systematically assessed through semi-structured validated survey. Total IgG, IgA IgM serum antibodies evaluated by an electrochemiluminescence immunoassay. A systematic literature meta-analysis...