A5100388752- Ocular Diseases and Behçet’s Syndrome
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Cerebral Venous Sinus Thrombosis
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Neuroinflammation and Neurodegeneration Mechanisms
- Drug-Induced Ocular Toxicity
- Orthopedic Infections and Treatments
- Ophthalmology and Eye Disorders
- Pharmacovigilance and Adverse Drug Reactions
- Corneal Surgery and Treatments
- Retinal Development and Disorders
- Ocular Infections and Treatments
- RNA regulation and disease
- Connexins and lens biology
- Corneal surgery and disorders
- Angiogenesis and VEGF in Cancer
- Multiple Sclerosis Research Studies
- Sinusitis and nasal conditions
- Ophthalmology and Visual Impairment Studies
- Infectious Diseases and Tuberculosis
- Long-Term Effects of COVID-19
- Cancer-related molecular mechanisms research
Capital Medical University
2011-2025
Beijing Tongren Hospital
2011-2025
Second Affiliated Hospital of Fujian Medical University
2024
Fujian Medical University
2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2020-2022
Chongqing Medical University
2020-2022
Qilu Hospital of Shandong University
2022
Second Hospital of Shandong University
2016-2021
Sun Yat-sen University
2010-2016
Third Affiliated Hospital of Sun Yat-sen University
2010
Faricimab is predominantlyprescribed for conditions such as age-related macular degeneration (AMD),diabetic edema (DME), and related to retinal veinocclusion (RVO-ME). Currently, a notable absence of large-scale, real-worldstudies focusing on the adverse reactions faricimab exists. Thisstudy assesses side effects by analyzing reports adverseevents (AEs) from FDA's AEReporting System (FAERS) database. Through disproportionality analysis, thisstudy substantiates drug's safety oversight. Our...
Recently, the practice of ordering routine postoperative laboratory tests in primary total hip arthroplasty (THA) has been challenged. This study aimed to evaluate utility after elective THA an Asian population and identify risk factors associated with abnormal test-related intervention.We retrospectively reviewed 395 consecutive patients who underwent at a single tertiary academic center. Patient clinical information test results were collected for analysis.A 349 (88.4%) had results; most...
To analyse miRNA regulation in a rat model of acute ocular hypertension (AOH).Acute (AOH) was induced the left eye adult albino rats by inserting cannula connected with saline container into anterior chamber. The contralateral served as control. Seven days later, animals were killed. Retinas used either for quantitative analysis retinal ganglion cells (RGCs) and microglial or array hybridization, qRT-PCR Western blotting.Anatomically, AOH caused axonal degeneration, significant loss RGCs...
Purpose. To predict visual acuity (VA) 1 month after anti-vascular endothelial growth factor (VEGF) therapy in patients with diabetic macular edema (DME) by using machine learning. Methods. This retrospective study included 281 eyes DME receiving intravitreal anti-VEGF treatment from January 1, 2019, to April 2021. Eighteen features electronic medical records and measurements data OCT images were extracted. The obtained November 2020, used as the training set; 2021, validation set. Six...
AIM: To investigate the neuroprotective effect of gastrodin on retinal ganglion cells (RGCs) in an acute ocular hypertension (AOH) rat model and to identify its possible mechanism. METHODS: AOH was performed a randomly selected eye by anterior chamber perfusion either received intraperitoneal injection with various concentrations or normal saline. After 2wk, rats were sacrificed. FluoroGold used label survival RGCs. Immunostaining anti-Iba1 flat mounts calculate microglia density cell layer...
Purpose. To investigate the clinical characteristics of Mooren’s ulcer in East China and to identify potential risk factors that affect recurrence ulcer. Methods. We reviewed medical records 95 patients (100 eyes) diagnosed with from May 2005 December 2014. The were classified into recurrent nonrecurrent groups followed up for 18 months. difference between two was estimated. group subdivided according history corneal infection perforation, respectively. time subgroups analyzed. Results....
To evaluate changes in the concentrations of placental growth factor (PlGF) and vascular endothelial factor-A (VEGF-A) aqueous humor patients with neovascular glaucoma (NVG) before after an intravitreal injection ranibizumab (IVR) to determine underlying correlation between levels.The prospective interventional comparative study involved 20 eyes surgery-required advanced NVG control subjects from January 2013 November 2013. The received IVR treatment surgery. Aqueous was collected at time...
Current research has not provided a consistent and qualitative description of MRI features in Leber hereditary optic neuropathy (LHON). Our study aims to investigate the findings pregeniculate visual pathway discuss their clinical significance LHON.Orbital was retrospectively analyzed for 53 patients with LHON (101 afflicted eyes) admitted Department Neurology, Beijing Tongren Hospital, Capital Medical University, from 2014 2019. We described imaging abnormalities discussed associations time...
Background Ecchymosis is one of the worrisome complications after total knee arthroplasty (TKA) and interferes with functional rehabilitation. Current clinical guidelines do not provide individualized approaches for patients ecchymoses. Methods In this study, we used thromboelastography (TEG) to determine coagulation state TKA then explore markers that predict occurrence ecchymosis events TKA. our cohort, were divided into ( n = 55) non-ecchymosis 137) groups according whether occurred...
Research on the relationship between mild COVID-19 and subsequent development of isolated optic neuritis (ON) with antibodies specific to myelin oligodendrocyte glycoprotein (MOG-ON) aquaporin 4 (AQP4-ON) is limited, particularly case-control studies that directly compare these conditions within same affected population.
Abstract Purpose Total Hip Arthroplasty (THA) is the primary treatment for hip diseases today. Nevertheless, total arthroplasty has its challenges, and one of these challenges potential incorrect execution preoperative planning process. Such errors can lead to complications such as loosening instability prosthesis leg length discrepancy. In this study, we used human phantoms investigate influence pelvic femoral factors on size selection in provide a reference standard clinical imaging...
Purpose: To report the clinical course and vascular endothelial growth factor (VEGF) levels in breast milk among three nursing women diagnosed with idiopathic choroidal neovascularization (CNV) before after intravitreal injection of conbercept. Methods: This was an observational case series. The main outcomes measures included best-corrected visual acuity (BCVA), anatomical features using optical coherence tomography, concentrations VEGF Results: BCVA increased, no ocular or systemic safety...
Since acquired immunodeficiency syndrome (AIDS) was reported for the first time in 1981, HIV-associated ocular complications have been gradually known by people. However, part of etiologies remained unknown. With development study, more and scholars consider primary optic neuropathy as etiology. This article introduces history related risk factors neuropathy. DOI: 10.3969/j.issn.1672-6731.2016.08.002
Objective To observe the ocular manifestations and therapeutic effect of multiple sclerosis (MS) neuromyelitis optica (NMO) with symptoms. Methods The clinical data 107 patients who was diagnosed MS NMO symptoms in our hospital were retrospectively analyzed, including 81 26 patients. counting erythocytes leukocyte, protein content oligoclonal bands detected by MRI cerebrospinal fluid (CSF) order to ensure diagnosis NMO. All had undergone regular ophthalmologic examination visual acuity,slit...