A5085600613- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Cervical Cancer and HPV Research
- Viral Infections and Outbreaks Research
- Bacterial Infections and Vaccines
- Vector-borne infectious diseases
- Antibiotic Resistance in Bacteria
- Viral gastroenteritis research and epidemiology
- Bartonella species infections research
- Virology and Viral Diseases
- Gut microbiota and health
- Leptospirosis research and findings
- Respiratory and Cough-Related Research
- COVID-19 Clinical Research Studies
- Bacterial biofilms and quorum sensing
- COVID-19 epidemiological studies
- Artificial Intelligence in Healthcare
- Oral microbiology and periodontitis research
- Radiomics and Machine Learning in Medical Imaging
- Genital Health and Disease
- Machine Learning and Data Classification
- Malaria Research and Control
- Ideological and Political Education
Peruvian University of Applied Sciences
2016-2025
Instituto de Investigación Nutricional
2017-2025
Universidad Nacional Agraria La Molina
2024
Konyang University
2022
University of Malaya
2022
Sunway University
2022
Health Protection Research Unit in Emerging and Zoonotic Infections at University of Liverpool
2022
University of Liverpool
2022
University of Jaffna
2022
National University of San Marcos
2016
Cardiometabolic traits are complex interrelated that result from a combination of genetic and lifestyle factors. This study aimed to assess the interaction between variants dietary macronutrient intake on cardiometabolic [body mass index, waist circumference, total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density triacylglycerol, systolic blood pressure, diastolic fasting serum glucose, insulin, glycated haemoglobin]. cross-sectional consisted 468 urban young adults...
IntroductionOropouche fever is an under-reported and emerging infectious disease caused by Oropouche virus (OROV). Its incidence under-estimated mainly due to clinical similarities with other endemic arboviral diseases the lack of specific diagnostic tests. We report first outbreak in a western region Peruvian Amazon Huanuco, Peru.MethodsA transversal study was carried out during Region Peru between January July 2016. Blood samples 268 patients acute febrile syndrome were collected analyzed...
At the end of 2019, a novel coronavirus denominated SARS-CoV-2 rapidly spread through world causing pandemic disease known as COVID-19. The difference in inflammatory response against infection among people living at different altitudes is variable not yet studied.A descriptive cross-sectional study was performed two Peruvian cities for comparison: Lima and Huaraz. Five important proinflammatory cytokines were measured including: IL-6, IL-2, IL-10, IFN-γ TNF-α using ELISA assays.A total 35...
The rapid expansion of the novel SARS-CoV-2 virus has raised serious public health concerns due to possibility misdiagnosis in regions where arboviral diseases are endemic. We performed first study northern Peru describe detection IgM antibodies febrile patients with a suspected diagnosis dengue and chikungunya fever.
Acute chikungunya virus infection often leads to chronic post-infection arthritis, but investigation and evaluation of treatment is hampered by the subjectivity symptoms. This study was designed evaluate ultrasound scores serum inflammatory markers as objective measures for severity post-chikungunya arthritis. Patients with acute were enrolled in a prospective followed up at 3, 6 12 months. Assessments included both physical exam standardised examination 40 joints. Symptom patient reported...
Arboviral diseases are one of the most common causes acute febrile illness (AFI) and a significant health problem in South America. In Peru, laboratory etiologic identification these infections occurs less than 50% cases, leading to underdiagnoses important emerging arboviruses.To assess prevalence Dengue (DENV), Oropouche (OROV), Chikungunya (CHIKV), Mayaro (MAYV) Zika (ZIKV) viruses patients with from Puerto Maldonado (Peru).Serum samples were obtained AFI during January 2016 March 2016. A...
Objective . To evaluate antibacterial and cytotoxic effect of 2 methanolic extracts Azadirachta indica Moringa oleifera against strains Enterococcus faecalis (ATCC 29212) in vitro Methods The were prepared the was evaluated using agar diffusion technique. minimum inhibitory concentration (MIC) determined microdilution method cytotoxicity cellular line MDCK. Results extract with most during first 24 48 hours , evidencing a growth inhibition zone 35.5 ± 1.05 44.83 0.98, respectively. MIC for...
The infection caused by Mayaro virus (MAYV), which presents as an acute febrile illness, is considered a neglected tropical disease. endemic and emerging pathogen in South America the Caribbean, responsible for occasional poorly characterized outbreaks. Currently there limited information about its expansion risk areas.A cross-sectional study was performed 10 urban primary care health centers Cajamarca region of Peru from January to June 2017. A total 359 patients with suspected illness were...
Introduction In the last years rapid expansion of multidrug-resistant A . baumannii strains have become a major health problem. Efflux pumps are group transport proteins that contribute to development antibiotic resistance. The aim this study was evaluate effect efflux pump inhibitor carbonyl cyanide 3-chlorophenylhydrazone (CCCP) on antimicrobial action imipenem and cefepime clinical Materials methods total 49 non-duplicate samples were collected during January through December 2018 from...
Oropouche fever is an infectious disease caused by the virus (OROV). The diagnosis and prediction of clinical picture continue to be a great challenge for clinicians who manage patients with acute febrile syndrome. Several symptoms have been associated OROV infection in syndrome; however, date, there no rule, which fundamental tool help approach this disease.To assess performance model based solely on signs diagnose syndrome.Validation study, included 923 syndrome registered Epidemiological...
Mycoplasma pneumoniae and Chlamydia are atypical pathogens responsible for pneumonia a leading cause of morbidity mortality in low income countries. The study objective is to determine the prevalence this Peruvian children with acute respiratory infections.A consecutive cross-sectional was conducted Lima, Peru from May 2009 September 2010. A total 675 admitted clinical diagnoses infections were tested detection by polymerase chain reaction (PCR), symptoms registered attending...
To determine the variations in composition of intestinal microbiota asymptomatic children infected with Helicobacter pylori comparison without infection. Children H. doubled their probability presenting 3 9 genera bacteria from gut microbiota, including: Proteobacteria (p = 0.008), Clostridium 0.040), Firmicutes 0.001) and Prevotella 0.006) to patients We performed a nutritional assessment found that growth stunting was statistically significantly higher 0.046).
Abstract Objective To describe frequency and clinical characteristics of MAYV infection in Piura, as well the association this pathogen with DENV. Results A total 86/496 (17.3%) cases were detected, which 54 mono-infection 32 co-infection DENV, accounting for 10.9% 6.4%, respectively. When evaluating monoinfection by main groups 18–39 40–59 years old, 25.9% 20.4% Co-infections more common age group those > 60 34.4% 21.9%, The most frequent presentation headaches (94.4%, 51/54) followed...
Pertussis diagnosis may go unrecognized when other pathogens, such as respiratory syncytial virus (RSV) circulate.A prospective cross-sectional study was conducted in Lima, Peru from January 2009 to September 2010. A total of 596 children under 5 years old admitted with clinical diagnoses acute infections were test for B. pertussis and RSV detection by polymerase chain reaction (PCR).The toxin IS481 genes detected 19.12% (114/596) the cases viruses (RSV-A RSV-B) identified 17.28% (103/596)...
Abstract Objective To evaluate the frequency of infection caused by Oropouche virus (OROV) in 496 patients with acute febrile disease (AFI), whose samples were obtained for analysis endemic arboviruses a previous investigation carried out 2016. Results OROV was detected 26.4% (131/496) serum from AFI. Co-infections Dengue (7.3%), Zika (1.8%) and Chikungunya (0.2%) observed. The most common clinical symptoms reported among infections headache 85.5% (112/131), myalgia 80.9% (106/131),...
Objective . To evaluate the in vitro adherence and viability of 3 bacterial species Streptococcus mutans (ATCC 25175), sanguinis 10556), Porphyromonas gingivalis 33277) on surfaces dental implants titanium, zirconium, their respective fixing screws. Methods Two analysis groups were formed: group 1 with titanium pillars 2 zirconium pillars, each Each these was included tubes cultures 33277). These samples incubated at 37°C under anaerobic conditions. Bacterial assessed by measurement change...
The addition of Biofire® FilmArray® Blood Culture Identification panel 2 (BCID2) to the antimicrobial stewardship program (ASP) could improve outcomes in bloodstream infections (BSI) patients with febrile neutropenia (FN). A pre- and post-quasi-experimental single-center study was conducted at a reference hospital Peru. Three groups were considered: BSI before ASP intervention (control group), after (group 1), plus BCID2 PCR Panel implementation 2). Overall, 93 identified (32 control, 30...
The loss of biodiversity and the effects climate change hurt agricultural production food security in Peru around world.The family farming sector (97% units -AU) faces numerous challenges when it comes to sustainably producing food.To sustain Peruvian agriculture face change, climate-smart (CSA) practices agrobiodiversity conservation are essential.This document characterizes level (index IDA) AUs Crisnejas basin analyzes impact elements that affect farmers' decisions apply multiple CSA...
To evaluate the susceptibility of Pseudomonas aeruginosa (P. aeruginosa) in vitro to ethanolic extracts obtained from five different Peruvian medicinal plants. The plants were chopped and soaked absolute ethanol (1:2, w/v). antibacterial activity compounds against P. was evaluated using cup-plate agar diffusion method. Maytenus macrocarpa ("Chuchuhuasi"), Dracontium loretense Krause ("Jergon Sacha"), Tabebuia impetiginosa ("Tahuari"), Eucalyptus camaldulensis Dehn (eucalyptus), Uncaria...
Acute respiratory infections (ARIs) represent an important cause of morbidity and mortality in children, remaining a major public health concern, especially affecting children under 5 years old from low-income countries. Unfortunately, information regarding their epidemiology is still limited Peru.A secondary data analysis was performed previous cross-sectional study conducted with probable diagnosis Pertussis January 2010 to July 2012. All samples were analyzed via Polymerase Chain Reaction...