- biodegradable polymer synthesis and properties
- Electrospun Nanofibers in Biomedical Applications
- Conducting polymers and applications
- Advanced Sensor and Energy Harvesting Materials
- Bone Tissue Engineering Materials
- Immune cells in cancer
- Viral Infections and Vectors
- Additive Manufacturing and 3D Printing Technologies
- Polymer Surface Interaction Studies
- Mosquito-borne diseases and control
- Pneumonia and Respiratory Infections
- Supramolecular Self-Assembly in Materials
- Polymer crystallization and properties
- Lymphoma Diagnosis and Treatment
- Microplastics and Plastic Pollution
- Chronic Lymphocytic Leukemia Research
- Advanced biosensing and bioanalysis techniques
- Peroxisome Proliferator-Activated Receptors
- Respiratory viral infections research
- Graphene and Nanomaterials Applications
- Antimicrobial agents and applications
- Electrochemical sensors and biosensors
- Ubiquitin and proteasome pathways
- Neuroscience and Neural Engineering
- Cancer, Lipids, and Metabolism
Universitat Politècnica de Catalunya
2016-2025
Louisiana State University Health Sciences Center New Orleans
2019-2023
Louisiana Cancer Research Center
2023
Louisiana State University
2023
University of Malaya
2022
Elisava Barcelona School of Design and Engineering
2015-2021
FC Barcelona
2014-2021
Clínica Diagonal
1998-2021
Valencia Catholic University Saint Vincent Martyr
2017
Hospital Juárez de México
2016
Composites of hydroxyapatite (HAp) are widely employed in biomedical applications due to their biocompatibility, bioactivity and osteoconductivity properties. In fact, the development industrially scalable hybrids at low cost high efficiency has a great impact, for example, on bone tissue engineering even as drug delivery systems. New nanocomposites constituted by HAp nanoparticles synthetic or natural polymers with biodegradable biocompatible characteristics have constantly been developed...
Electroactive and biocompatible fibrous scaffolds have been prepared characterized using polyaniline (PAni) doped with dodecylbenzenesulfonic acid (DBSA) combined poly(lactic acid) (PLA) PLA/poly(ethylene glycol) (PEG) mixtures. The composition of simple core-shell fibers, which obtained by both uniaxial coaxial electrospinning, respectively, has corroborated Fourier-transform infrared micro-Raman spectroscopies. Morphological studies suggest that the incorporation PEG enhances packing PLA...
Melt electrospinning has been developed in the last decade as an eco-friendly and solvent-free process to fill gap between advantages of solution need a cost-effective technique for industrial applications. Although benefits using melt compared are impressive, there still challenges that should be solved. These mainly concern improvement polymer processability with reduction degradation enhancement fiber stability; achievement good control over size especially production large scale...
In a prospective passive diarrhea surveillance cohort study of 1,034 infants low socioeconomic communities in Lima, Peru, we determined the prevalence and antimicrobial drug susceptibility diarrheagenic Escherichia coli . The E. was 29% (161 557) children with gastroenteritis 30% (58 195) control group without diarrhea. most common pathogens were enteroaggregative (EAEC) (14%), enteropathogenic (EPEC) (7%), diffusely adherent (DAEC) (4%), enterotoxigenic (ETEC) (4%). Diarrheagenic as...
This review provides a current status report of the field concerning preparation fibrous mats based on biodegradable (e.g., aliphatic polyesters such as polylactide or polycaprolactone) and conducting polymers polyaniline, polypirrole polythiophenes). These materials have potential biomedical applications tissue engineering drug delivery systems) can be combined to get free-standing nanomembranes nanofibers that retain better properties their corresponding individual components. Systems...
Ultrasound technology was proved as an efficient processing technique to obtain micro-molded specimens of polylactide (PLA) and polybutylene succinate (PBS), which were selected examples biodegradable polyesters widely employed in commodity specialty applications. Operational parameters such amplitude, molding force time successfully optimized prepare samples with a decrease the number average molecular weight lower than 6%. Ultrasonic waves also seemed ideal energy source provide effective...
Electrospun poly(ε-caprolactone) (PCL) microfibers loaded with poly(3,4-ethylenedioxythiophene) nanoparticles (PEDOT NPs) and curcumin diameter of 3.9 ± 0.7 μm have been prepared subsequently characterized using different spectroscopic techniques, scanning electron microscopy, atomic force microscopy. PEDOT NPs, which are mainly located inside the PCL microfibers, exhibit a 99 21 nm. PEDOT- curcumin-containing behave as extracellular cell matrices, facilitating spreading enhancing...
IntroductionOropouche fever is an under-reported and emerging infectious disease caused by Oropouche virus (OROV). Its incidence under-estimated mainly due to clinical similarities with other endemic arboviral diseases the lack of specific diagnostic tests. We report first outbreak in a western region Peruvian Amazon Huanuco, Peru.MethodsA transversal study was carried out during Region Peru between January July 2016. Blood samples 268 patients acute febrile syndrome were collected analyzed...
At the end of 2019, a novel coronavirus denominated SARS-CoV-2 rapidly spread through world causing pandemic disease known as COVID-19. The difference in inflammatory response against infection among people living at different altitudes is variable not yet studied.A descriptive cross-sectional study was performed two Peruvian cities for comparison: Lima and Huaraz. Five important proinflammatory cytokines were measured including: IL-6, IL-2, IL-10, IFN-γ TNF-α using ELISA assays.A total 35...
The rapid expansion of the novel SARS-CoV-2 virus has raised serious public health concerns due to possibility misdiagnosis in regions where arboviral diseases are endemic. We performed first study northern Peru describe detection IgM antibodies febrile patients with a suspected diagnosis dengue and chikungunya fever.
The development of effective drug delivery systems is a major challenge in cancer therapy, gene and infectious disease treatment because its low bioavailability, rapid clearance, toxicity towards non-targeted healthy tissues. This review discusses how PEGylation, the covalent attachment poly(ethylene glycol) (PEG), enhances pharmacokinetic profiles drug-containing nanosystems through "stealth effect" that avoids immune system detection improves circulation times different nano-delivery...