A5074423724- Antifungal resistance and susceptibility
- Viral gastroenteritis research and epidemiology
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Resistance in Bacteria
- Salmonella and Campylobacter epidemiology
- Pneumonia and Respiratory Infections
- Bacterial Identification and Susceptibility Testing
- Fungal Infections and Studies
- Parasitic Infections and Diagnostics
- Bacterial biofilms and quorum sensing
- Escherichia coli research studies
- Streptococcal Infections and Treatments
- Respiratory and Cough-Related Research
- Parasitic infections in humans and animals
- Congenital Anomalies and Fetal Surgery
- Pneumocystis jirovecii pneumonia detection and treatment
- Vibrio bacteria research studies
- Biochemical and Structural Characterization
- Pharmaceutical and Antibiotic Environmental Impacts
- Yersinia bacterium, plague, ectoparasites research
- Mycobacterium research and diagnosis
- Pharmacological Effects of Natural Compounds
- Clostridium difficile and Clostridium perfringens research
- Antibiotics Pharmacokinetics and Efficacy
- Neonatal and Maternal Infections
Tehran University of Medical Sciences
2015-2024
University of Tehran
2022-2023
Iran University of Medical Sciences
2018
Children's Medical Center
2011-2014
Motamed Cancer Institute
2013
The clinical importance of Staphylococcus aureus (S. aureus) is attributed to notable virulence factors, surface proteins, toxins, and enzymes as well the rapid development drug resistance. aim this study was compare occurrence factors produced by S. strains isolated from children in an Iranian referral children's hospital.The presence genes encoding for enterotoxins A (sea), B (seb), C (sec), D (sed), TSST-1 (tsst), exfoliative toxin (eta), (etb) were detected Multiplex polymerase chain...
Summary Invasive candidiasis is a major cause of morbidity and mortality in children. However, limited data are available on the epidemiology this infection paediatric settings Iran. The aim study was to determine prevalence, microbial epidemiology, risk factors clinical outcomes associated with candidaemia intensive care units at Children's Medical Center, Tehran, All blood other normally sterile specimen cultures positive for Candida species were included. Isolates identified by...
The aim of this study was to determine the prevalence virulence-associated genes and enterobacterial repetitive intergenic consensus PCR (ERIC-PCR) analysis Campylobacter spp. isolated from children with diarrhea in Iran.A total 200 stool specimens were obtained under 5 years during July 2012 2013. Detection C. jejuni coli performed by standard biochemical molecular methods. presence genetic diversity isolates examined using ERIC-PCR analyses.A 12 (6%) patients including 10 (4.5%) 2 (1.5%)...
Epidemiological studies show that parasitic inections are among the most common infections and one of biggest health problems society worldwide. Children at school age have highest morbidity compared with other ages. Therefore, by treating these children, disease burden in total population is reduced. In this study, prevalence infection children referred to Children's Medical Center was different years. retrospective cross-sectional subjects were under 13 years who Laboratory during 18...
Transmission of Pseudomonas aeruginosa along the food chain could cause gastrointestinal infections. To show this involvement, prevalence, putative virulence genotype, and antibiotic resistance phenotype P. isolates from stool 1482 patients with community hospital acquired diarrhea were compared 87 environmental samples. The results showed infection in 3.4% cases, while 57.4% vegetable samples contaminated. Significantly higher frequency lasB (98%), aprA exoY exoS (90%), but lower rate exoT...
Encapsulated Streptococcus pneumoniae strains cause high morbidity and mortality, mainly in countries with no pneumococcal conjugate vaccines (PCVs) immunization program. This study investigated the epidemiological changes of S. isolates including serotype distribution antimicrobial susceptibility Tehran, Iran.A total 80 samples were collected from patients admitted to Shariati hospital over two periods. Half February September 2017 other half July 2018 March 2019. The testing PCV-13...
Staphylococcus aureus can cause several infections. Its capability to form biofilm has been reported be a vital property involved in the bacteria's pathogenesis. Various genes contributing formation have not yet completely clarified. This study was designed evaluate factors influencing adherence and S. isolated from paediatric patients. One hundred ninety-seven isolates were obtained pediatric patients confirmed with phenotypic molecular examinations. Antimicrobial susceptibility testing...
ABSTRACT Here, we described the efficacy of colistin sub-minimum inhibitory concentrations (sub-MICs) on biofilm-forming activity, host epithelial cell adherence, and invasion capacity Acinetobacter baumannii strains collected from children admitted to Children’s Medical Center Hospital. Biofilm formation potency A. clinical isolates was measured using a 96-well microtiter plate assay. Distribution biofilm-related genes, including bap , abaI ompA csuE bla PER-1 detected by PCR. The mRNA...
As data on pediatric invasive candidiasis (IC) and the antifungal susceptibility pattern of associated isolates are scarce in Iran, this study aimed to determine species distribution profile Candida isolated from patients with suspected or documented IC. A total 235 yeast strains recovered normally sterile body fluids admitted at intensive care units Children's Medical Centre, Tehran, were identified using CHROMagar Candida, molecular methods (ITS PCR-RFLP sequencing), MALDI-TOF....
Multiple yeast species can cause human disease, involving superficial to deep-seated infections. Treatment of these infections depends on the accurate identification causative agents; however, reliable methods are not available in many laboratories, especially resource-limited settings. Here, a new multiplex assay for rapid and low-cost pathogenic yeasts is described.A two-step named YEAST PLEX that comprises four tubes identifies 17 clinically important common rare was designed evaluated....
Background: Emerging antibacterial resistance rates and extended-spectrum-β-lactamase producing Escherichia coli recovered from urinary tract infections (UTI) is an increasing problem in different regions, limiting therapeutic options. Objectives: The aim of this study was the detection blaTEM, blaSHV blaCTX-M genes among strains causing Urinary Tract Infection children Iran. Materials Methods: A total 100 isolates were collected urine specimens patients with UTI who had referred to Children...
Background: Salmonella and Shigella infections are important public health concerns among children. The emergence of antibiotic resistance amongst particularly isolates has posed serious problems in antimicrobial treatment worldwide. Data on local patterns essential to design suitable guidelines. Objectives: aim the present study was determine prevalence drug susceptibility species addition detection extended-spectrum β-lactamase producing diarrhea samples pediatric patients. Methods: A...
Background: The aspects of the epidemiology bloodstream Candida infections including clinical features, causal agents, underlying conditions, and risk factors have not been well-defined in Iranian pediatric patients. aim this observational study was to identify uncommon species isolated from blood other normally sterile specimens neonates children admitted intensive care units at Children's medical center, Tehran, Iran. Methods: carried out prospectively on patients < 16 years, who were...