A5071131975- Aquaculture Nutrition and Growth
- Marine Bivalve and Aquaculture Studies
- Aquaculture disease management and microbiota
- Genetic and phenotypic traits in livestock
- Genetic diversity and population structure
- Animal Genetics and Reproduction
- Genomics and Phylogenetic Studies
- Aquatic Invertebrate Ecology and Behavior
- Genetic Mapping and Diversity in Plants and Animals
- CRISPR and Genetic Engineering
- Agricultural Systems and Practices
- Epigenetics and DNA Methylation
- Fish Biology and Ecology Studies
- Parasite Biology and Host Interactions
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Calcium Carbonate Crystallization and Inhibition
- Congenital heart defects research
- Animal Virus Infections Studies
- Invertebrate Immune Response Mechanisms
- Chromosomal and Genetic Variations
- Identification and Quantification in Food
- Microfinance and Financial Inclusion
- Child Nutrition and Water Access
- Fish biology, ecology, and behavior
- Muscle Physiology and Disorders
Benchmark Animal Health (United Kingdom)
2025
Roslin Institute
2013-2024
University of Edinburgh
2013-2024
Benchmark (United Kingdom)
2024
Biotechnology and Biological Sciences Research Council
2017
Austral University of Chile
2009-2012
The Pacific oyster (Crassostrea gigas) is a bivalve mollusc with vital roles in coastal ecosystems and aquaculture globally. While extensive genomic tools are available for C. gigas, highly contiguous reference genomes required to support both fundamental applied research. Herein we report the creation annotation of chromosome-level assembly gigas.
Abstract SNP arrays are enabling tools for high-resolution studies of the genetic basis complex traits in farmed and wild animals. Oysters critical importance many regions from both an ecological economic perspective, oyster aquaculture forms a key component global food security. The aim our study was to design combined-species, medium density array Pacific (Crassostrea gigas) European flat (Ostrea edulis), test performance this on populations multiple locations, with focus populations....
SNP arrays are powerful tools for high-resolution studies of the genetic basis complex traits, facilitating both selective breeding and population genomic research. The European seabass (Dicentrarchus labrax) gilthead seabream (Sparus aurata) two most important fish species Mediterranean aquaculture. While programmes increasingly underpin stock supply this industry, selection is not yet widespread. Genomic has major potential to expedite gain, particularly traits practically impossible...
Abstract Enhancing host resistance to infectious disease has received increasing attention in recent years as a major goal of farm animal breeding programs. Combining field data with genomic tools can provide opportunities understand the genetic architecture resistance, leading new for control. In current study, genome-wide association study was performed assess Tilapia lake virus (TiLV), one biggest threats affecting Nile tilapia ( Oreochromis niloticus ); key aquaculture species globally....
Abstract The European flat oyster ( Ostrea edulis L.) is a bivalve naturally distributed across Europe, which was an integral part of human diets for centuries, until anthropogenic activities and disease outbreaks severely reduced wild populations. Despite growing interest in genetic applications to support population management aquaculture, reference genome this species lacking date. Here, we report chromosome‐level assembly annotation the Flat genome, generated using Oxford Nanopore,...
Abstract Background Viral nervous necrosis (VNN) is an important viral disease threatening global aquaculture sustainability and affecting over 50 farmed ecologically fish species. A major QTL for resistance to VNN has been previously detected in European sea bass, but the underlying causal gene(s) mutation(s) remain unknown. To identify mechanisms genetic factors underpinning we employed integrative analyses of multiple functional genomics assays bass. Results The estimated heritability was...
Abstract Tilapia are among the most important farmed fish species worldwide, and fundamental for food security of many developing countries. Several genetically improved Nile tilapia (Oreochromis niloticus) strains exist, such as iconic Genetically Improved Farmed (GIFT), breeding programs typically follow classical pedigree-based selection. The use genome-wide single-nucleotide polymorphism (SNP) data can enable an understanding genetic architecture economically traits acceleration gain via...
Knowledge of population structure and genetic diversity within between wild farmed populations gilthead sea bream (Sparus aurata) European seabass (Dicentrarchus labrax) is important to achieve sustainable aquaculture production these species assess the risk impacts fish escaped from farms. Previous studies on have been based a limited number markers samples. In this study, features were assessed using samples 24 seabream 25 distributed throughout Mediterranean Sea, 3 Atlantic populations....
Blue mussels from the genus Mytilus are an abundant component of benthic community, found in high latitude habitats. These foundation species relevant to aquaculture industry, with over 2 million tonnes produced globally each year. Mussels withstand a wide range environmental conditions and edulis complex readily hybridize regions where their distributions overlap. Significant effort has been made investigate consequences stress on mussel physiology, reproductive isolation, local adaptation....
Nile tilapia (
Infectious Salmon Anaemia Virus (ISAV) is an Orthomixovirus that represents a large problem for salmonid aquaculture worldwide. Current prevention and treatment methods are only partially effective. Genetic selection genome engineering have the potential to develop ISAV resistant salmon stocks. Both strategies can benefit from improved understanding of genomic regulation pathogenesis. Here, we used single-cell RNA sequencing Atlantic cell line provide first high dimensional insight into...
Abstract Background Myostatin (MSTN) belongs to the transforming growth factor-β superfamily and is a potent negative regulator of skeletal muscle development in mammals. Most teleost fish possess two MSTN paralogues. However, as consequence recent whole genome-duplication event, salmonids have four: MSTN-1 (− 1a - 1b ) MSTN-2 2a 2b ). Evidence suggests that plays role regulation growth. In current study, MSTN-1b gene was re-sequenced screened for SNP markers commercial population Atlantic...
Salmon rickettsial septicaemia (SRS), caused by the bacteria Piscirickettsia salmonis (P. salmonis), is responsible for significant mortality in farmed Atlantic salmon Chile. Currently there are no effective treatments or preventive measures this disease, although genetic selection genome engineering to increase resistance SRS promising strategies. The accuracy and efficiency of these strategies usually influenced available biological background knowledge disease. aim study was investigate...
Abstract Background Megaleporinus macrocephalus (piauçu) is a Neotropical fish within Characoidei that presents well-established heteromorphic ZZ/ZW sex-determination system and thus, constitutes good model for studying W Z chromosomes in fishes. We used PacBio reads Hi-C to assemble chromosome-level reference genome M. . generated family segregation information construct genetic map, pool-seq of males females characterize its sex system, RNA-seq highlight candidate genes determination....
The European flat oyster (
Adult specimens of M. galloprovincialis from Concepción Bay and chilensis Yaldad Bay, Chile, were transferred to the laboratory produce crosses "pure" "hybrid" species in order evaluate early larval development growth.These variables are important for understanding dynamics these two mussel this potential hybrid zone where they occur sympatrically.The study showed that fertilization occurred all significant differences not detected between pure lines hybrids terms percentage eggs developed...
Abstract Background Pacu ( Piaractus mesopotamicus ) is one of the most important Neotropical aquaculture species from South America. Disease outbreaks caused by Aeromonas hydrophila infection have been considered significant contributors to declining levels pacu production. The current implementation genomic selection for disease resistance has adopted as a powerful strategy improvement in fish species. This study aimed investigate genetic architecture A. via Genome-Wide Association Study...
Abstract Background Megaleporinus macrocephalus (piauçu) is a Neotropical fish within Characoidei that presents well-established heteromorphic ZZ/ZW sex determination system and thus constitutes good model for studying W Z chromosomes in fishes. We used PacBio reads Hi-C to assemble chromosome-level reference genome M. macrocephalus. generated family segregation information construct genetic map, pool sequencing of males females characterize its system, RNA highlight candidate genes...
Abstract Background The Nile tilapia ( Oreochromis niloticus ) is the third most important freshwater fish for aquaculture. Its success directly linked to continuous breeding efforts focusing on production traits such as growth rate and weight. Among those elite strains, Genetically Improved Farmed Tilapia (GIFT) programme initiated by WorldFish now distributed worldwide. To accelerate development of GIFT strain through genomic selection, a high-quality reference genome necessary. Results...
A set of expressed sequence tag-simple repeat (EST-SSR) markers for the genus Mytilus was developed through bioinformatic mining GenBank public database. total 33 782 EST sequences from were downloaded and screened di-, tri- tetranucleotide, with 1274 containing SSR markers. Nine microsatellite characterized in californianus a number alleles per locus ranging two to six, observed expected heterozygosities 0.490 0.730 0.510 0.860 respectively. Cross-species amplification achieved several...
Lipid-related traits are important candidates for a breeding goal gilthead seabream, because they affect both fish and human health, as well production efficiency. However, to date there have been very few estimates of genetic parameters these traits, the relationship between fatty acids other never reported seabream. Therefore, aim this study was estimate genomic heritability relationships fat deposition individual muscle in commercial population seabream using novel ~30 k MedFish SNP...