Maria-Lauretta Orji

ORCID: 0000-0001-7082-8506
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About
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Research Areas
  • HIV/AIDS Research and Interventions
  • Viral Infections and Outbreaks Research
  • Adolescent Sexual and Reproductive Health
  • Disaster Response and Management
  • HIV/AIDS Impact and Responses
  • HIV, Drug Use, Sexual Risk
  • HIV Research and Treatment
  • HIV-related health complications and treatments
  • Poisoning and overdose treatments
  • Restraint-Related Deaths
  • Global Security and Public Health
  • Reproductive Health and Technologies
  • Parasites and Host Interactions
  • Gender Roles and Identity Studies
  • Poverty, Education, and Child Welfare
  • Sexual Assault and Victimization Studies
  • Blood transfusion and management
  • Ovarian function and disorders
  • Pregnancy and preeclampsia studies
  • Pancreatic function and diabetes
  • Foreign Body Medical Cases
  • Vaccine Coverage and Hesitancy
  • Airway Management and Intubation Techniques
  • Long-Term Effects of COVID-19
  • Pediatric health and respiratory diseases

Federal Teaching Hospital Abakaliki
2017-2025

Ebonyi State University
2020-2025

University of Nigeria
2020

Attitudes and beliefs regarding HIV among adolescents young adults (AYA) may influence practices that increase the risk of transmission. The study aimed to determine attitudes senior secondary students their sexual practices. It was a cross-sectional descriptive involved 1,200 aged 14-24 years in schools Abakaliki. Information obtained using two-part pre-tested questionnaire tested 6-item another part sought information on biodata p-value < 0.05 statistically significant. median (IQR) age...

10.60787/nmj.v65i6.606 article EN PubMed 2025-01-29

Abstract Background Nigeria has the largest global burden of HIV new infections in children despite and national concerted efforts at reduction mother-to-child transmission HIV. The goal this study was to determine associations between maternal characteristics, practices infection among mothers living with Methods This is a hospital-based descriptive cross-sectional study. Information obtained using interviewer-administered questionnaire from 240 participants. Data were analyzed SPSS version...

10.1093/pubmed/fdae092 article EN Journal of Public Health 2024-06-13

Background: Malaria contributes significantly to under-5 morbidity and mortality in Sub-Saharan African countries including Nigeria. The rollback malaria (RBM) initiative millennium developmental goal 6 are the programs targeted at reduction burden. target year here is 2015; it would be needful determine impact of these on lives at-risk population. Objectives: To caregivers' perception utilization insecticide-treated mosquito net (ITN) for their children/wards under 5 years age. Methods: It...

10.4103/aam.aam_64_16 article EN Annals of African Medicine 2018-01-01

The signs and symptoms of Lassa fever are initially indistinguishable from other febrile illnesses common in the tropics complications pregnancy. Surviving during pregnancy is rare. Only few cases have been documented. antiviral drug choice ribavirin.A 25-year-old multigravida farmer with who was thought to malaria at 29 weeks gestation. Further changes her clinical state laboratory tests led a confirmation fever. Liver enzymes were markedly deranged packed cell volume 27%. She commenced on...

10.1016/j.ijid.2019.08.023 article EN cc-by-nc-nd International Journal of Infectious Diseases 2019-08-26

Only one recommendation currently exists for the treatment of Lassa fever (LF), which is ribavirin administered in conjunction with supportive care. This primarily based on evidence generated from a single clinical trial that was conducted more than 30 years ago-the methodology and results have recently come under scrutiny. The requirement novel therapeutics reassessment therefore urgent. However, significant amount work now needs to be undertaken ensure future trials LF can consistently...

10.1371/journal.pntd.0010089 article EN cc-by PLoS neglected tropical diseases 2022-01-06

Fetal weight estimation is important in the management of labour and delivery. This study aimed to compare accuracy clinical ultrasound methods fetal estimation. was a prospective involving 110 term cephalic singleton pregnancies delivered within 24 hours using Johnson's Dare's formulae at Tertiary hospital Abakaliki, Nigeria. The data were analysed with Stata 11 software. sonographic 10% actual birth (ABW) 68.2% significantly greater than (23.6%), (26.4%), combined (27.1%). overestimated...

10.1080/01443615.2019.1571567 article EN Journal of Obstetrics and Gynaecology 2019-04-25

Background: Sleep hygiene may be defined as a set of habits and guidelines that promote consistently restful sufficient sleep at night, consequently leading to alertness during the day. The study was aimed determining pattern factors contributing poor among children attending outpatient clinic in Federal Teaching Hospital Abakaliki (FETHA). Materials Methods: In this cross-sectional descriptive study, data were collected from May 2012 September 2012. Structured questionnaire administered...

10.4103/1118-8561.223168 article EN Sahel Medical Journal 2017-01-01

The prevalence and case fatality rates of Pediatric Lassa fever disease (LFD) are not well documented. This study was aimed at determining the prevalence, pattern outcome LFD. It a prospective observational study. A total 183 subjects that met criteria for LFD suspects were recruited consecutively subjected to virus PCR test. Structured questionnaire used collect information. Of children recruited, 24 tested positive PCR, giving positivity rate 13.1%. Mean duration illness presentation 8.54...

10.20944/preprints202005.0269.v1 preprint EN 2020-05-16

COVID-19 infection has continued to pose a very serious health threat mankind globally despite all efforts geared toward curbing its spread. More worrisome recently is the report from different parts of world on re-infection those treated and recovered with COVID -19 patients thus making containment virus even more difficult. Of fact that lung, vital human organ major site being attacked by cases. If quick action not taken early enough, it may lead outright death patient. A lung infection,...

10.5539/gjhs.v12n12p64 article EN Global Journal of Health Science 2020-10-19

Introduction: Infection by human immunodeficiency virus results in immune destruction, while studies among the Ethiopian immigrants Israel showed that chronic helminthiasis induces dysregulation. With destruction of CD4+ cell and consequently progression to AIDS, host may be more susceptible invading organisms such as helminths. This study was aimed at determining effect state on prevalence intensity helminth infection HIV infected children two hospitals Abakaliki.Material Methods: It a...

10.3126/jnps.v37i1.16474 article EN cc-by Journal of Nepal Paediatric Society 2017-10-04

Introduction: The emotional and psychosocial issues surrounding HIV infection make status disclosure herculean task. Many caregivers are unwilling to disclose because they afraid of possible unpleasant outcome. objective this study were determine the prevalence rate effect on ART adherence.Material Methods: It was a cross sectional that involved consecutive recruitment 94 confirmed infected children aged 5-17 years. Structured questionnaire used obtain information socio-demographic,...

10.3126/jnps.v37i3.18730 article EN cc-by Journal of Nepal Paediatric Society 2018-06-07

Background: The adolescent phase of life is characterized by the desire for independence, experimentation, and heightened peer influence. These may affect HIV prevention, care, treatment, support in adolescents. Objective: This study was aimed at determining outcome intervention factors responsible treatment failure among adolescents on first-line antiretroviral therapy (ART). Materials Methods: It an interventional cohort that studied 88 ART. An interviewer-administered questionnaire used...

10.4103/njm.njm_90_21 article EN cc-by-nc-sa Nigerian Journal of Medicine 2021-09-01

Background: Lassa fever disease is an infectious with high case fatality occurring in countries West, Central, and East Africa. It endemic Nigeria Ebonyi State, Southeast Nigeria. Knowledge of the cause, mode transmission, clinical presentations are invaluable prevention control.Objective: The study was therefore aimed at assessing level knowledge among caregivers that presented children out-patient a tertiary hospital State.Methods: hospital-based cross-sectional carried out within 6 months...

10.4314/njp.v49i1.9 article EN Nigerian Journal of Paediatrics 2022-05-02

Background: Human immunodeficiency virus (HIV) infection causes a derangement in growth. Antiretrovirals promote immune function restoration and improvement the quality of life. Variables such as poor adherence to drugs unsuppressed viral load may negatively influence growth HIV-infected children. The study aimed at determining males aged 8–17 years Abakaliki who were on antiretrovirals. Methods: A case–control hospital-based study, involving 80 matched for age socioeconomic class with...

10.4103/njm.njm_158_20 article EN cc-by-nc-sa Nigerian Journal of Medicine 2021-03-01

Cryptic pregnancy is defined as lack of awareness until the last weeks gestation or during labour and delivery but in cryptic scam, mothers feigned pregnancies that never existed.We report a total four cases HIV infected infants said to have been delivered by negative mothers. All are above 40 years age with range 9 18 infertility marriage. The scam was neither confirmed test nor obstetric scan. Diagnosis infection made at infancy following positive rapid antigen test.The menace Nigeria...

10.1093/pubmed/fdad048 article EN Journal of Public Health 2023-05-05

Button battery ingestion is a form of foreign-body usually seen among children. Its could be symptom free and sometimes fatal. The interval between swallowing final destination the button has some clinical importance to its management. This case report an eight-year-old boy, who ingested 25 mm-sized which was detected in lower esophagus by plain X-ray, managed conservatively with honey, later passed out stool after 36 h.

10.4103/njm.njm_193_21 article EN cc-by-nc-sa Nigerian Journal of Medicine 2022-03-01

Neonatal diabetes mellitus (NDM) is a rare disorder characterized by persistent hyperglycaemia within the first six months of life, resulting from inadequate insulin production, hence need for exogenous therapy. This can be life-threatening and often associated with adverse consequences if undiagnosed. Hence, high index suspicion, prompt investigation early diagnosis, in an attempt to provide appropriate cost-effective We report three cases infants that presented were managed neonatal...

10.4103/njm.njm_29_22 article EN cc-by-nc-sa Nigerian Journal of Medicine 2022-05-01

HIV infection, through various mechanisms causes a derangement in sexual maturation. This study compared the Marshal and Tanner staging of HIV-infected uninfected males. The aim was to determine maturation male children infected with on HAART Abakaliki.this cross-sectional comparative involving 80 boys aged 8-17 years counterparts matched for age socio-economic class. Stages (testicular size pubic hair) were determined according method proposed by Marshall Tanner. testicular measured using...

10.11604/pamj.2022.42.133.29305 article EN PubMed 2022-01-01

Background: Lassa virus disease (LVD) is of public health concern in endemic countries Africa. Majority infections are asymptomatic while symptomatic cases can mimic other infections. This study was aimed at determining the clinical features seen children with positive PCR and symptoms that determine outcome LVD an community, Southeast Nigeria.&#x0D; Materials methods: It a prospective observational enrolled 183 met criteria for suspects. These were subjected to polymerase chain reaction...

10.4314/njp.v48i4.4 article EN Nigerian Journal of Paediatrics 2022-11-07
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