A5050639612- Viral Infections and Outbreaks Research
- Disaster Response and Management
- Viral Infections and Vectors
- Global Health and Surgery
- Vector-borne infectious diseases
- Zoonotic diseases and public health
- Yersinia bacterium, plague, ectoparasites research
- Simulation-Based Education in Healthcare
- Innovations in Medical Education
- COVID-19 Impact on Reproduction
- Respiratory viral infections research
- Mosquito-borne diseases and control
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and healthcare impacts
- Delphi Technique in Research
- COVID-19 epidemiological studies
University of Oxford
2019-2023
World Health Organization
2019
Oxford Research Group
2019
Only one recommendation currently exists for the treatment of Lassa fever (LF), which is ribavirin administered in conjunction with supportive care. This primarily based on evidence generated from a single clinical trial that was conducted more than 30 years ago-the methodology and results have recently come under scrutiny. The requirement novel therapeutics reassessment therefore urgent. However, significant amount work now needs to be undertaken ensure future trials LF can consistently...
We describe a pilot of the Clinical REsearch During Outbreaks (CREDO) initiative, training curriculum for researchers in epidemic-prone low- and middle-income countries who may respond to disease outbreaks. Participants reported improved confidence their ability conduct such research overall satisfaction with course structure, content, training.
Background There is limited epidemiological evidence on Lassa fever in pregnant women with acute gaps prevalence, infection incidence, and risk factors. Such would facilitate the design of therapeutic vaccine trials control programs. Our study sought to address some these by estimating seroprevalence seroconversion women. Methodology/Principal findings We conducted a prospective hospital-based cohort between February December 2019 Edo State, Southern Nigeria, enrolling at antenatal clinic...
Background Evidence from previous studies suggest that Lassa fever, a viral haemorrhagic fever endemic to West Africa has high case fatalities, particularly in pregnancy. While there have been remarkable innovations vaccine development, with some vaccines undergoing early clinical trials. An understanding of antibody kinetics and immune responses will support design development. However, is currently no evidence on the (LASV) Our study sought estimate efficiency transplacental transfer LASV...