Xinghong Ding

ORCID: 0000-0001-7090-9445
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Research Areas
  • Magnetic confinement fusion research
  • Systemic Lupus Erythematosus Research
  • Particle accelerators and beam dynamics
  • Ionosphere and magnetosphere dynamics
  • Superconducting Materials and Applications
  • Solar and Space Plasma Dynamics
  • Liver Disease Diagnosis and Treatment
  • Immune Response and Inflammation
  • Gut microbiota and health
  • Fusion materials and technologies
  • Cytokine Signaling Pathways and Interactions
  • Inflammatory Bowel Disease
  • Natural product bioactivities and synthesis
  • Rheumatoid Arthritis Research and Therapies
  • Genetic Associations and Epidemiology
  • Atherosclerosis and Cardiovascular Diseases
  • Biological and pharmacological studies of plants
  • Lipid metabolism and disorders
  • Nuclear reactor physics and engineering
  • Pharmacological Effects of Natural Compounds
  • T-cell and B-cell Immunology
  • Ginseng Biological Effects and Applications
  • Phytochemicals and Antioxidant Activities
  • Cancer survivorship and care
  • Traditional Chinese Medicine Analysis

Zhejiang Chinese Medical University
2011-2025

Wuhan Donghu University
2025

ORCID
2021

Southwestern Institute of Physics
2003-2020

Analysis and Testing Centre
2013

National Agency for New Technologies, Energy and Sustainable Economic Development
2011

Culham Centre for Fusion Energy
2011

Institute for Plasma Research
2011

Institute of Plasma Physics
2011

ITER
2011

The β-induced Alfvén eigenmode (BAE) excited by energetic electrons has been identified for the first time both in Ohmic and electron cyclotron resonance heating plasma HL-2A. features of instability, including its frequency, mode number, propagation direction, can be observed magnetic pickup probes. frequency is comparable to that continuum accumulation point lowest gap induced shear continuous spectrum due finite β effect, it proportional velocity at thermal ion held constant. experimental...

10.1103/physrevlett.105.185004 article EN Physical Review Letters 2010-10-26

This study was carried out to evaluate the utilization probability of fibrous root part (FRP) Bletilla striata, which usually discarded and harvesting pseudobulb (PSP). The chemical composition, total phenolic content, DPPH radical scavenging activity, Ferric-reducing antioxidant power tyrosinase inhibition activity were compared between FRP PSP. Antioxidant pro-oxidant effect as well antitumor extract PSP analyzed by in vitro cell system well. Thin layer chromatography high performance...

10.1371/journal.pone.0058004 article EN cc-by PLoS ONE 2013-02-28

The purpose of this study was to investigate the effect astragalus polysaccharides (APSs), active constituents astragalus, in treatment hepatocellular carcinoma (HCC) and their potential as a promising candidate for future anticancer drug development. Astragalus polysaccharide administered at different doses HCC H22-bearing mice antitumor effects. Results revealed that APS inhibited growth H22 cells with tumor inhibition rate 400 mg·kg-1 group 59.01%. significantly increased spleen thymus...

10.1177/1559325816685182 article EN cc-by-nc Dose-Response 2017-01-03

ABSTRACT Both pore size and distribution evenness are of great importance to achieve the desirable performance aerogels. For aerogels prepared by freeze‐drying techniques, formation is directly related control ice crystal during freezing process. This study aimed compare impacts addition three kinds antifreeze protectants (trehalose, L‐Lysine monohydrochloride, hydroxypropyl methylcellulose [HPMC]) on frozen konjac glucomannan/starch sol, characteristics corresponding Results showed that...

10.1002/star.70014 article EN Starch - Stärke 2025-04-11

Cardamonin has promising potential in cancer prevention and therapy by interacting with proteins modifying the expressions activities, including factors of cell survival, proliferation, angiogenesis. In our precious study, we have demonstrated that cardamonin suppressed vascular endothelial growth factor- (VEGF-) induced angiogenesis as evaluated mouse aortic ring assay. It is also known microRNAs (miRNAs) play important roles Herein, hypothesized whether antiangiogenesis effect human...

10.1155/2015/501581 article EN cc-by BioMed Research International 2015-01-01

The impact of impurity ions on a pedestal has been investigated in the HL-2A Tokamak, at Southwestern Institute Physics, Chengdu, China. Experimental results have clearly shown that during $H$-mode phase, an electromagnetic turbulence was excited edge plasma region, where exhibited peaked profile. It found double critical gradients are responsible for triggering turbulence. Strong stiffness profile observed cyclic transitions between $I$-phase and regime. suggest underlying physics...

10.1103/physrevlett.117.045001 article EN Physical Review Letters 2016-07-22

Development of a fully functional dressing that can be applied throughout wound healing remains challenging. In this study, Bletilla striata polysaccharide (BSP) and the ethanol extract B. (EEB) were physically blended vacuum freeze-dried into new medical with various functions, such as hemostasis, anti-inflammatory, antibacterial promotion. The in vivo vitro blood coagulation evaluation results showed most obvious hemostasis effects coming from EEB25 sponge was probably due to good water...

10.1016/j.matdes.2021.109806 article EN cc-by-nc-nd Materials & Design 2021-05-06

Tetrastigma hemsleyanum Diels et Gilg (Sanyeqing, SYQ) has traditionally been used to treat inflammation, high fever and improve immune function of patients. Polysaccharides have proved be one the important components SYQ. Previous studies confirmed antipyretic antitumor effects polysaccharides from SYQ (SYQP), clarified that SYQP could enhance immunity through TLR4 signalling pathway. However, there were more possibilities for mechanism by which exerted immunomodulatory role in acute...

10.3389/fphar.2022.838873 article EN cc-by Frontiers in Pharmacology 2022-03-11

A correlation between mental illness and systemic rheumatoid arthritis (RA) has been observed in several prior investigations. However, little is known about the causative relationship them. The present study aimed to systematically investigate potential association genetically determined RA. Two-sample bidirectional Mendelian randomization (MR) analysis was performed using publicly released genome-wide studies (GWAS). We selected independent genetic variants associated with four illnesses...

10.3390/jcm12030944 article EN Journal of Clinical Medicine 2023-01-25

Abstract Background The guts of mammals are home to trillions microbes, forming a complex and dynamic ecosystem. Gut microbiota is an important biological barrier for maintaining immune homeostasis. Recently, the use antibiotics clear gut has gained popularity as low cost easy-to-use alternative germ-free animals. However, effect duration antibiotic cocktail on microbiome unclear, more importantly, dramatic changes in intestinal tissue morphology local response rarely reported. Results We...

10.1186/s12866-024-03424-z article EN cc-by BMC Microbiology 2024-07-31

Two peptides of Pt-A (Glu-Asn-Trp 429 Da) and Pt-B (Glu-Gln-Trp 443 were isolated from venom liquor Deinagkistrodon acutus . Their antiplatelet aggregation effects evaluated with platelet-rich human plasma in vitro ; the respective IC 50 was 66 μ M 203 M. Both exhibited protection on ADP-induced paralysis mice. After ADP administration, time different concentration lasted as following: 80 mg/kg (152.8 ± 57.8 s) < 40 (163.5 59.8 20 (253.5 74.5 4 clopidogrel (a positive control, 254.5 41.97...

10.1155/2015/412841 article EN Evidence-based Complementary and Alternative Medicine 2015-01-01

Despite the increasing incidence of aplastic anemia in China, few studies have explored its effect on patients' quality life from perspective these patients. In fact, patients with disorder live disease for a long time, and need to face variety difficult realities, including multiple symptoms drug side effects, heavy burden medical costs, difficulties social reintegration, negative emotional distress. Therefore, this study used descriptive qualitative research explore direct rich...

10.1186/s13023-023-02993-y article EN cc-by Orphanet Journal of Rare Diseases 2023-12-21

Systemic lupus erythematosus (SLE) is characterized by poor regulation of the immune response leading to chronic inflammation and multiple organ dysfunction. Glucocorticoid (GC) currently one main treatments. However, a high dose or prolonged use GC may result in glucocorticoid-induced osteoporosis (GIOP). Jiedu Quyu Ziyin decoction (JP) effective treating SLE previous clinical studies have proved that JP can prevent treat steroid (SLE-GIOP). We aim examine JPs mechanism on SLE-GIOP through...

10.1155/2023/8942415 article EN cc-by Journal of Immunology Research 2023-03-28

The aim of the Tore Supra tokamak is to address physics and technology issues long pulse discharges. For this purpose, equipped with two actively cooled Lower Hybrid Current Drive (LHCD) antennas (f = 3.7GHz), designed operate in 1000s pulses. One these recently installed passive active multijunction (PAM) antenna, whose design chosen for an LHCD system ITER. first experiments PAM antenna have shown extremely encouraging results terms reflection coefficient behaviour power handling. maximum...

10.1063/1.3665002 article EN AIP conference proceedings 2011-01-01
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