- Analytical Chemistry and Chromatography
- Antibiotics Pharmacokinetics and Efficacy
- Biological and pharmacological studies of plants
- Synthesis and Biological Evaluation
- Wound Healing and Treatments
- Polysaccharides and Plant Cell Walls
- Effects and risks of endocrine disrupting chemicals
- Immune Response and Inflammation
- Analytical Methods in Pharmaceuticals
- Consumer Market Behavior and Pricing
- Gut microbiota and health
- Microfluidic and Capillary Electrophoresis Applications
- Immune Cell Function and Interaction
- Auction Theory and Applications
- Analytical chemistry methods development
- Traditional Chinese Medicine Analysis
- Phytochemistry and Biological Activities
- Phytochemistry and biological activity of medicinal plants
- Inflammasome and immune disorders
- Essential Oils and Antimicrobial Activity
- Plant tissue culture and regeneration
- Planarian Biology and Electrostimulation
- Immune cells in cancer
- Natural product bioactivities and synthesis
- Barrier Structure and Function Studies
Zhejiang Chinese Medical University
2018-2025
Meizu (China)
2022-2024
National Medical Products Administration
2022-2023
ZheJiang Institute For Food and Drug Control
2017-2019
Columbia University
1992
Tetrastigma hemsleyanum Diels et Gilg is a traditional Chinese herbal medicine with high medicinal value, and antitumor, antioxidant anti-inflammatory biological activities. However, while several studies have focused on flavonoids in tubers, there are few the enhanced immune effect of polysaccharides (THP). In this study, we evaluated antitumor THP lung tumor model explored mechanism activity through intestinal flora. addition, cyclophosphamide (CTX)-induced immunosuppression was used to...
The healing process of a diabetic wound (DW) is often impeded by series interrelated factors, including severe infection, persistent inflammation, and excessive oxidative stress. Therefore, it particularly crucial to develop medical dressing that can address these issues simultaneously. To this end, different ratios Bletilla striata polysaccharide (BSP) berberine (BER) were physically blended with Carbomer 940 (CBM940) composite hydrogel as dressing. BSP/BER was characterized using SEM,...
Tetrastigma Hemsleyanum Diels et Gilg (Sanyeqing, SYQ), a traditional herb native to China, has been widely used in the treatment of inflammatory diseases, febrile convulsions and dysentery. Previous studies have demonstrated hypoglycemic, anti-inflammatory anti-pyretic effects polysaccharides from SYQ (SYQP). However, role SYQP acute lung injury (ALI) remained unknown. Our present study aimed explore protective ALI explained its underlying mechanism. In vivo, Balb/c mice were...
The management of diabetic ulcers poses a significant challenge worldwide, and persistent hyperglycemia makes patients susceptible to bacterial infections. Unfortunately, the overuse antibiotics may lead drug resistance prolonged infections, contributing chronic inflammation hindering healing process. To address these issues, photothermal therapy technique was incorporated in preparation wound dressings. This innovative solution involved formulation self-healing injectable hydrogel matrix...
Diabetic ulcers (DUs) usually suffer from severe infections, persistent inflammation, and excessive oxidative stress during the healing process, which led to microenvironmental alternation severely impede DU healing, resulting in a delayed wound healing. Therefore, it is particularly important develop medical dressing that can address these problems simultaneously. To this end, self-healing composite hydrogels were prepared study utilizing Bletilla striata polysaccharide (BSP) Berberine...
Abstract Background Bletilla striata is a traditional Chinese medicine used to treat hemorrhage, scald, gastric ulcer, pulmonary diseases and inflammations. In this study, we investigated bioactivity of the effective fraction B. (EFB) in reducing inflammatory cytokine production induced by water or organic extracts PM 2.5 . Methods were collected analyzed chromatographic system inductively coupled plasma mass spectrometer. Cell viability was measured using MTS...
Development of a fully functional dressing that can be applied throughout wound healing remains challenging. In this study, Bletilla striata polysaccharide (BSP) and the ethanol extract B. (EEB) were physically blended vacuum freeze-dried into new medical with various functions, such as hemostasis, anti-inflammatory, antibacterial promotion. The in vivo vitro blood coagulation evaluation results showed most obvious hemostasis effects coming from EEB25 sponge was probably due to good water...