- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Systemic Sclerosis and Related Diseases
- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Cardiovascular Effects of Exercise
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Anesthesia and Sedative Agents
- Cardiac tumors and thrombi
- Cardiac, Anesthesia and Surgical Outcomes
- Pericarditis and Cardiac Tamponade
- Ultrasound and Hyperthermia Applications
- Acute Myocardial Infarction Research
- Diagnosis and Treatment of Venous Diseases
- Cardiovascular Syncope and Autonomic Disorders
- Venous Thromboembolism Diagnosis and Management
- Chemotherapy-induced cardiotoxicity and mitigation
- Takotsubo Cardiomyopathy and Associated Phenomena
- Viral Infections and Immunology Research
- Pulmonary Hypertension Research and Treatments
- Lipoproteins and Cardiovascular Health
Marche Polytechnic University
2016-2025
Istituto Nazionale di Riposo e Cura per Anziani
2025
Istituti di Ricovero e Cura a Carattere Scientifico
2025
Ospedali Riuniti di Ancona
2020-2023
Ospedali Riuniti Umberto I
2020-2022
Azienda Ospedaliero Universitaria Ospedali Riuniti
2021-2022
Buckinghamshire Healthcare NHS Trust
2018
Wycombe General Hospital
2018
Background Systemic sclerosis is characterised by progressive cutaneous and organ fibrosis. Among all organs, a subclinical heart involvement difficult to detect through conventional imaging. Design We evaluated whether speckle tracking-derived global longitudinal strain could help early systolic dysfunction in systemic patients without overt clinical involvement. Methods A case–control, single-centre study on 52 age gender-matched controls. Patients with structural disease, failure, atrial...
Abstract Aims Albeit often asymptomatic, heart involvement in systemic sclerosis (SSc) represents a negative prognostic factor, accounting for nearly one-fourth of all deaths. Global longitudinal strain (GLS) is accurate detecting patients with SSc and no overt cardiac disease allows early detection monitoring, but its association clinical endpoints has not been tested so far. The primary outcome was the between left right GLS mortality causes. secondary hospitalizations. Methods results A...
Abstract Introduction The prediction of ventricular tachyarrhythmias among patients with implantable cardioverter defibrillators is difficult available clinical tools. We sought to assess whether in heart failure (HF) and reduced ejection fraction defibrillators, physiological sensor‐based HF status, as summarized by the HeartLogic index, could predict appropriate device therapies. Methods Five hundred sixty‐eight consecutive ( n = 158, 28%) or cardiac resynchronization...
Abstract Aims HeartLogic algorithm combines data from multiple implantable defibrillators (ICD)‐based sensors to predict impending heart failure (HF) decompensation. A treatment protocol manage alerts is not yet known, although decongestive adjustments are the most frequent alert‐triggered actions reported in clinical practice. We describe implementation of for remote monitoring HF patients, and we evaluate approach diuretic dosing timing intervention patients with device alerts. Methods The...
Abstract Introduction Comparison data on management of device‐related complications and their impact patient outcome healthcare utilization between subcutaneous implantable cardioverter–defibrillator (S‐ICD) transvenous ICD (TV‐ICD) are lacking. We designed this prospective, multicentre, observational registry to compare the rate, nature, long‐term requiring surgical revision patients undergoing S‐ICD or TV‐ICD implantation. Methods Results A total 1099 consecutive who underwent implantation...
Implantable loop recorder (ILR) is still underutilized in clinical practice, especially the setting of elderly patients with recurrent, traumatic, unexplained syncope. Data on actual risk traumatic syncopal recurrence during ILR monitoring this specific patient are lacking.Prospective, multicentre registry enrolling consecutive undergoing insertion for unexplained, In a proportion enrolled patients, remote (RM) was used device follow-up. The and non-traumatic recurrences observation were...
Cardiac amyloidoses (CAs) are an increasingly recognised group of infiltrative cardiomyopathies associated with high risk adverse cardiac events. We sought to characterise the characteristics and clinical value right ventricular (RV) electroanatomic voltage mapping (EVM) in CA.
Tachycardiomyopathy (TCM) is an underestimated cause of reversible left ventricle dysfunction. The aim this study was to identify the predictors recurrence and incidence major cardiovascular events in TCM patients without underlying structural heart disease (pure TCM). prospective, observational enrolled all consecutive pure patients. diagnosis suspected admitted for failure (HF) with a reduced ejection fraction concomitant persistent arrhythmia. Pure confirmed after clinical...
Cardiac involvement in patients with systemic sclerosis (SSc) is frequent and represents a negative prognostic factor. Recent studies have described subclinical heart of both the right ventricle (RV) left (LV) via speckle-tracking-derived global longitudinal strain (GLS). It currently unknown if SSc-related cardiomyopathy progresses through time. Our aim was to assess progression cardiac SSc GLS.This prospective study enrolling 72 consecutive diagnosis no structural disease nor pulmonary...