A5076338368- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiomyopathy and Myosin Studies
- Neurological disorders and treatments
- Cardiovascular Function and Risk Factors
- ECG Monitoring and Analysis
- Cardiac Valve Diseases and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Effects of Exercise
- Viral Infections and Immunology Research
- Mechanical Circulatory Support Devices
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Health Systems, Economic Evaluations, Quality of Life
- Heart Rate Variability and Autonomic Control
- Advanced MRI Techniques and Applications
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Muscle activation and electromyography studies
- Neuroscience and Neural Engineering
- Antiplatelet Therapy and Cardiovascular Diseases
Policlinico S.Orsola-Malpighi
2016-2025
University of Bologna
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2025
Azienda USL di Bologna
2018-2024
ERN GUARD-Heart
2024
Johns Hopkins Medicine
2022-2024
Johns Hopkins University
2022-2024
Policlinico Umberto I
2024
Arcispedale Sant'Anna
2024
Istituto delle Scienze Neurologiche di Bologna
2022-2023
The ESC Guidelines represent the views of and were produced after careful consideration scientific medical knowledge evidence available at time their publication.The is not responsible in event any contradiction, discrepancy, and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies.Health professionals are encouraged take fully into account when exercising clinical...
The ESC Guidelines represent the views of and were produced after careful consideration scientific medical knowledge evidence available at time their publication.The is not responsible in event any contradiction, discrepancy, and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies.Health professionals are encouraged take fully into account when exercising clinical...
Asymptomatic atrial fibrillation (AF) can expose patients to the risk of stroke. The primary objective this study was assess incidence thromboembolic events in relationship with CHADS(2) (congestive heart failure, hypertension, age >or=75 years, diabetes mellitus, and prior stroke, or transient ischemic attack) score AF presence/duration. secondary compare intermittent versus continuous monitoring strategies.Data from an implanted pacemaker a history were analyzed. Thromboembolic quantified...
Pacemakers, implantable cardiac defibrillators, and resynchronization therapy devices are potentially life-saving treatments for a number of conditions, but not without risk. Most concerning is the risk electronic device (CIED) infection, which associated with significant morbidity, increased hospitalizations, reduced survival, healthcare costs. Recommended preventive strategies such as administration intravenous antibiotics before implantation well recognized. Uncertainties have remained...
Infections after placement of cardiac implantable electronic devices (CIEDs) are associated with substantial morbidity and mortality. There is limited evidence on prophylactic strategies, other than the use preoperative antibiotics, to prevent such infections.
Abstract Pacemakers, implantable cardiac defibrillators, and resynchronization therapy devices are potentially life-saving treatments for a number of conditions, but not without risk. Most concerning is the risk electronic device (CIED) infection, which associated with significant morbidity, increased hospitalizations, reduced survival, healthcare costs. Recommended preventive strategies such as administration intravenous antibiotics before implantation well recognized. Uncertainties have...
We evaluated the performance of 3 different left ventricular leads (LV) for resynchronization therapy: bipolar (BL), quadripolar (QL) and active fixation (AFL). enrolled 290 consecutive CRTD candidates implanted with BL (n = 136) or QL 97) AFL 57). Over a minimum 10 months follow-up, we assessed: (a) composite technical endpoint (TE) (phrenic nerve stimulation at 8 V@0.4 ms, safety margin between myocardial phrenic threshold <2V, LV dislodgement failure to achieve target pacing site), (b)...
Abstract With the global increase in device implantations, there is a growing need to train physicians implant pacemakers and implantable cardioverter-defibrillators. Although are international recommendations for indications programming, no consensus date regarding implantation technique. This document founded on systematic literature search review, from an task force. It aims fill gap by setting standards implantation.
The extravascular implantable cardioverter–defibrillator (ICD) has a single lead implanted substernally to enable pause-prevention pacing, antitachycardia and defibrillation energy similar that of transvenous ICDs. safety efficacy ICDs are not yet known.
In patients with atrial fibrillation (AF), stroke risk stratification schema do not consider AF parameters. The aim of the study is to assess impact combining factors continuous burden monitoring.In this retrospective 568 implanted a DDDR-P pacemaker (AT-500; Medtronic) and history were continuously monitored for 1 year.During follow-up, 14 (2.5%) had thromboembolic event. Patients divided into 3 groups: ≤5 minutes per day (AF-free; n=223 [39%]), >5 but <24 hours (AF-5 minutes; n=179 [32%]),...
The ALternate Site Cardiac ResYNChronization (ALSYNC) study evaluated the feasibility and safety of left ventricular endocardial pacing (LVEP) using a market-released lead implanted via single pectoral access by novel atrial transseptal delivery system.ALSYNC was prospective clinical investigation with minimum 12-month follow-up in 18 centres cardiac resynchronization therapy (CRT)-indicated patients, who had failed or were unsuitable for conventional CRT. ALSYNC system comprises...
Background: Remote monitoring (RM) in patients with advanced heart failure and cardiac resynchronization therapy defibrillators (CRT-D) may reduce delays clinical decisions by transmitting automatic alerts. However, this strategy has never been tested specifically patient population, alerts for lung fluid overload, a European setting. Objective: The main objective of Phase 1 (presented here) is to evaluate if RM able time from device-detected events decisions. Methods: In multicenter...
BackgroundBiventricular endocardial pacing (BiV ENDO) is a therapy for heart failure patients who cannot receive transvenous epicardial cardiac resynchronization (CRT) or have not responded adequately to CRT. BiV ENDO CRT can be delivered by new wireless LV system (WiSE-CRT system; EBR Systems, Sunnyvale, CA), without the requirement lifelong anticoagulation.ObjectiveThe purpose of this study was assess safety and efficacy WiSE-CRT during real-world clinical use in an international...
Heparin administration in COVID-19 patients is recommended by expert consensus, although evidence about dosage, duration and efficacy are limited. We aim to investigate the association between different dosages of low molecular weight heparin (LMWH) mortality among hospitalized patients.Retrospective study 450 laboratory-confirmed admitted Sant'Orsola Bologna Hospital from March 01 April 10, 2020. Clinical, laboratory treatment data were collected analyzed. The in-hospital treated with...
There is growing evidence of cardiac injury in COVID-19. Our purpose was to assess the prognostic value serial electrocardiograms COVID-19 patients.
Cocaine consumption is a significant global problem, with an estimated 20 million users worldwide. Sudden cardiac death frequently reported in this population, particularly among individuals <40 years of age. The role underlying inherited heart disorders these cases remains largely unexplored. We report the case patient who suffered cocaine-induced sudden death, where dedicated program investigating unexplained deaths young identified SCN5A-related disease. hypothesize that diseases may...
The aims of our study were to investigate the meaning local atrial activation and its behavior during paroxysmal fibrillation effect overdrive pacing on activity.Twenty-five patients with lone underwent electrophysiological study. Functional effective refractoriness was determined. Mean fifth percentile values 100 consecutive intervals (FF) evaluated at three sites either arrhythmia onset or self-termination (or minute 5). A high-voltage burst performed after 6 minutes stable in 10 patients....
Background and Purpose— Emery-Dreifuss muscular dystrophy (EDMD) is a rare inherited disorder associated with cardiac involvement. We investigated the spectrum relevance of manifestations EDMD, focusing on bradyarrhythmias tachyarrhythmias (including atrial fibrillation/flutter), embolic stroke, heart failure. Methods Results— Eighteen patients (age 42.8±19.6 years) genetically confirmed X-linked (n=10, including 3 carriers) or autosomal dominant (n=8) EDMD were followed for period ranging...
Phrenic stimulation (PS) may hinder left ventricular (LV) pacing. We prospectively observed its prevalence in consecutive patients with cardiac resynchronization therapy (CRT) devices.In the years 2003 to 2006, 197 received a CRT device. PS and LV threshold measurements were carried out at implantation 6-month follow-up. reverse remodeling was assessed by echocardiography before lead placement lateral/posterolateral 86% of patients. Both occurred most frequently pacing sites (P<0.001)....