- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Valve Diseases and Treatments
- Rheumatoid Arthritis Research and Therapies
- Pharmaceutical Economics and Policy
- Coronary Interventions and Diagnostics
- Psoriasis: Treatment and Pathogenesis
- Spondyloarthritis Studies and Treatments
- Chronic Lymphocytic Leukemia Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Infective Endocarditis Diagnosis and Management
- Acute Myocardial Infarction Research
- Biosimilars and Bioanalytical Methods
- Cardiac and Coronary Surgery Techniques
- Lipoproteins and Cardiovascular Health
- Medication Adherence and Compliance
- Emergency and Acute Care Studies
- HIV/AIDS drug development and treatment
- Atrial Fibrillation Management and Outcomes
- Hepatitis C virus research
- Pharmaceutical studies and practices
- Cardiac Imaging and Diagnostics
- Bipolar Disorder and Treatment
- Cardiac pacing and defibrillation studies
- Pharmaceutical Practices and Patient Outcomes
- Schizophrenia research and treatment
Maria Cecilia Hospital
2023-2025
Center for Outcomes Research and Clinical Epidemiology
2012-2021
Health Economics and Outcomes Research (United Kingdom)
2011-2021
University of Bologna
2007-2016
University of Macerata
2013
Policlinico S.Orsola-Malpighi
2008-2012
Maasstad Ziekenhuis
2012
Deutsches Herzzentrum der Charité
2012
Seoul National University Hospital
2012
Erasmus University Rotterdam
2012
Background— Most studies of amyloidotic cardiomyopathy consider as a single entity the 3 main systemic cardiac amyloidoses: acquired monoclonal immunoglobulin light-chain (AL); hereditary, mutated transthyretin-related (ATTRm); and wild-type (ATTRwt). In this study, we compared diagnostic/clinical profiles these types amyloidosis. Methods Results— We conducted longitudinal study 233 patients with clear-cut diagnosis by type amyloidosis (AL, n=157; ATTRm, n=61; ATTRwt, n=15) at 2 large...
In this study, we compared the cumulative risk of major adverse cardiac events (MACE) patients with distal unprotected left main coronary artery (ULMCA) stenosis those ostial and midshaft lesions treated drug-eluting stent (DES). The survey promoted by Italian Society Invasive Cardiology on ULMCA was an observational study involving 19 high-volume centres. We enrolled 1111 DES. Major were defined as death, myocardial infarction, target lesion revascularization. Three hundred thirty-four had...
This study investigated whether a clown doctor intervention could reduce preoperative anxiety in children hospitalized for minor surgery and their parents. A randomized controlled trial was conducted with 77 119 parents: the group consisted of 52 accompanied preoperating room by parents ( n = 89) two clowns while comparison only. The significantly reduced children’s anxiety: benefited from clown’s presence showed better adjustment than group. Mothers Comparison Group higher anxiety.
Phrenic stimulation (PS) may hinder left ventricular (LV) pacing. We prospectively observed its prevalence in consecutive patients with cardiac resynchronization therapy (CRT) devices.In the years 2003 to 2006, 197 received a CRT device. PS and LV threshold measurements were carried out at implantation 6-month follow-up. reverse remodeling was assessed by echocardiography before lead placement lateral/posterolateral 86% of patients. Both occurred most frequently pacing sites (P<0.001)....
Background— Distal unprotected left main coronary artery (ULMCA) stenosis represents a technical challenge for interventional cardiologists. In this study, we compared 2-year clinical outcomes of different stenting strategies in patients with distal ULMCA treated drug-eluting stents. Methods and Results— The survey promoted by the Italian Society Invasive Cardiology on was an observational study percutaneous intervention. selected Seven hundred seventy-three were eligible study: 456 1 stent...
Background: Infective endocarditis (IE) is a serious public health concern due to its high morbidity and lethality. This study investigates epidemiological trends in aortic valve endocarditis, focusing on sex-related differences microbial etiology surgical outcomes over 15-year period. Methods: From January 2010 2024, 608 patients underwent cardiac surgery for IE at our center. Of these, 274 received isolated replacement. retrospective, single-center analyzes these cases. Results: Despite...
Background: The minimally invasive approach, performed via ministernotomy, is now often preferred for isolated aortic valve replacement (AVR). However, its benefits in patients with prior cardiac surgery remain unclear. This article compares traditional and reoperative cases. Methods: A retrospective analysis of 382 who underwent AVR between January 2010 June 2024 divided them into two groups: 309 (80.1%) had a full sternotomy, while 73 (19.1%) upper ministernotomy. Results: Significant...
Objective: Minimally invasive combined mitral and aortic valve surgery is still uncommon. We report our experience performing multiple procedures through a right-sided minithoracotomy. Methods: present an observational case series with retrospective analysis of 38 patients who underwent double right anterior thoracotomy from November 2013 to 2023. Results: The median age population was 72 years, 61% were female patients. EuroSCORE II 2.27. Three (7.9%) had redo operations. cardiopulmonary...
The clinical performance of drug-coated balloons (DCBs) for the treatment femoro-popliteal lesions may depend on specific device used. There is limited evidence safety and efficacy paclitaxel-coated Stellarex® long (>180 mm) lesions. This a single arm, prospective, open label, observational study including symptomatic patients with undergoing endovascular revascularization DCB. primary endpoints were DCB over time. Secondary represented by functional outcomes. Ninety-five (median age 72,...
Background: This study evaluates the outcomes of isolated mitral valve surgery for infective endocarditis performed via conventional full sternotomy or minimally invasive right minithoracotomy. While (MIS) is well-established elective procedures, its role in remains less explored due to complexity disease. Methods: A retrospective analysis 134 patients who underwent between January 2010 and March 2024 was conducted. Patients were divided into two groups based on surgical approach: (n = 94)...
Comparative studies on the longevity of implantable cardioverter-defibrillators (ICDs) among different manufacturers have never been reported. Longevity ICD devices implanted from 1 January 2000 to 31 December 2002 was prospectively investigated according their type and manufacturer.Longevity single-chamber (SC), double-chamber (DC), biventricular (CRT-D) ICDs Medtronic (MDT), Guidant (GDT), St Jude Medical (SJM) measured in all patients who required device replacement. The observation...
Aims The aims of this study were to evaluate if the risk cardiovascular events and all‐cause mortality was higher in presence hyperkalaemia (HK) patients with heart failure (HF) treated renin–angiotensin–aldosterone system inhibitors (RAASi), investigate cohort increased among HK non‐optimal adherence RAASi therapy. Methods results In retrospective based on administrative databases five Italian Local Health Units, all adult a HF diagnosis between January 2010 December 2017 included only they...
Background: Despite advanced diagnosis and treatment, infective endocarditis (IE) is a potentially life-threatening condition. The impact of COVID-19 on the outcome surgical treatment IE uncertain. aim this study was to analyze incidence, characteristics, outcomes surgically treated before after pandemic. Methods: This retrospectively analyzed data 535 patients who underwent valve procedures for between January 2010 December 2022 in single cardiac surgery center. Patients were divided into...