A5027469339- Blood Pressure and Hypertension Studies
- Health Systems, Economic Evaluations, Quality of Life
- Medication Adherence and Compliance
- Pharmaceutical Economics and Policy
- Pharmaceutical Practices and Patient Outcomes
- Lipoproteins and Cardiovascular Health
- Diabetes Treatment and Management
- Diabetes Management and Research
- Hepatitis C virus research
- Atrial Fibrillation Management and Outcomes
- Bone health and osteoporosis research
- Hip and Femur Fractures
- Psoriasis: Treatment and Pathogenesis
- Antiplatelet Therapy and Cardiovascular Diseases
- Inflammatory mediators and NSAID effects
- Spondyloarthritis Studies and Treatments
- Bone health and treatments
- Bipolar Disorder and Treatment
- Venous Thromboembolism Diagnosis and Management
- Hepatitis B Virus Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Rheumatoid Arthritis Research and Therapies
- Asthma and respiratory diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Education
Health Economics and Outcomes Research (United Kingdom)
2002-2020
Center for Outcomes Research and Clinical Epidemiology
2007-2019
Local Government Association
2018
Ospedale "Santa Maria delle Croci" di Ravenna
2002
Oral glucose-lowering medications are associated with excess risk of heart failure (HF). Given the absence comparative data among drug classes, we performed a retrospective study in 32 Health Services 16 Italian regions accounting for population 18 million individuals, to assess association between HF and use sulphonylureas, DPP-4i, glitazones. We extracted on patients type 2 diabetes who initiated treatment thiazolidinediones, or sulphonylureas alone combination metformin during an accrual...
The objective of the research was to perform a clinical practice‐based analysis how long patients remain on various antihypertensive drugs. An administrative database listing patient baseline characteristics, drug prescriptions, and hospital admissions used. All new users drugs, ≥20 years age, receiving first prescription for diuretics, β blockers, calcium channel angiotensin‐converting enzyme inhibitors, or angiotensin II receptor antagonists between January 1, 2000, December 31, were...
Abstract: Poor medication adherence leads to worsening of clinical outcomes and increases healthcare costs, especially in the context chronic conditions. The effects new COVID-19 infection measures taken response outbreak are further increasing concerns about adherence. Patients with diseases, many whom older adults, have been strongly recommended stay at home avoid social contacts even family members, who often provide support for regular use therapies. Moreover, mobilization health...
Objective: The purpose of this study was to assess the changes in adherence treatment, patients who switched from perindopril and/or amlodipine as a monotherapy (single-pill therapy, SPT) or two-pill combinations fixed-dose combination (FDC) therapy.Methods: A large retrospective cohort study, three Italian Local Health Units, performed. All adult subjects received at least one prescription anti-hypertensive drugs between January 1, 2010 and December 31, 2014 were selected. date first...
To describe the therapeutic pathways of patients with psoriasis (PSO) and psoriatic arthritis (PsA) before after treatment biological therapies in a real-world setting to determine relative consumption health care resources.Retrospective observational study.Real-life clinical 5 Italian local units.A total 351 male female at least 1 prescription for drug from January 1, 2010 December 31, 2013; concomitant rheumatoid arthritis, ankylosing spondylitis, or Crohn's disease were excluded.The major...
To identify clinical and economic indicators of pharmacoutilization antihypertensive drugs.4614 subjects receiving a first prescription for amlodipine, atenolol, fosinopril, indapamide, or losartan were included in the study. All prescriptions filled during study period from January 1, 1997 to December 31, 1998 considered. A retrospective analysis was carried out on information recorded drug database. The percentage patients continuing, discontinuing, switching initial treatment, duration...
Introduction: The objective of this study was twofold: 1) to assess the residual cardiovascular (CV) risk among patients treated with statins according guidelines and at recommended dosages; 2) difference, if any, in frequency CV events when were other lipid-lowering agents alongside statins. Methods: A retrospective observational including one local health unit conducted. Administrative databases linked laboratory test database order collect cholesterol values baseline. Patients included...
Comparative analysis of budesonide/formoterol and fluticasone/salmeterol combinations in COPD patients: findings from a real-world an Italian setting Valentina Perrone, Diego Sangiorgi, Stefano Buda, Luca Degli Esposti CliCon S.r.l. Health, Economics Outcomes Research, Ravenna, Italy Aim: The objective this study was to evaluate the different outcomes associated with use compared fixed patients "real-world" setting. included exacerbation rates health care costs.Patients methods: An...
Introduction. Preliminary evidence suggests that hypercholesterolemia is associated to an increased risk develop hypertension. We aimed at evaluating the association between low-density lipoprotein cholesterol (LDL-C) level and incidence of new onset hypertension in a large population sample.Materials methods. A population-based cohort 20,074 subjects with least one LDL-C measurement July 2006 June 2007 free antihypertensive treatment (AHT) baseline was followed from date until death or 31...
It is well known that hypertension control non-satisfactory, but it not clear how many hypertensive patients can be controlled in real life. We addressed this question implementing a simple, multifaceted improvement strategy family practice.Eighteen General Practitioner (GPs) agreed upon simple including: 1) the use of occasional direct/indirect contacts (prescription refilling) to decrease missing blood pressure (BP) recording, and increase therapeutic adherence, 2) home BP measurements...
This study aimed to: 1) describe treatment patterns and drug utilization profile (in terms of therapeutic strategy used, switch, persistence consumption variation) among adult patients affected by rheumatoid arthritis (RA), 2) estimate the health care resource its associated direct cost for management RA patients.A retrospective cohort analysis, using administrative databases six Local Health Units in Italy, was performed. All with a confirmed diagnosis between January 1, 2010 December 31,...
The use of Combination AntiRetroviral Therapy (cART) has decreased the morbidity and mortality patients infected with HIV. However, adherence to cART remains crucial prevent virological failure disease progression. aim this study was assess treatment among treated Single Tablet Regimen (STR) or multi‐pill regimens based on Protease Inhibitors (PI), Non‐Nucleoside Reverse‐Transcriptase (NNRTI), raltegravir (RAL). An observational retrospective cohort analysis administrative clinical databases...
Disease progression and health care resource consumption in patients affected by hepatitis C virus real practice setting Valentina Perrone, Diego Sangiorgi, Stefano Buda, Luca Degli Esposti CliCon S.r.l. Health, Economics & Outcomes Research, Ravenna, Italy Introduction: Hepatitis (HCV) infection represents serious problems worldwide is a major contributor to end-stage liver disease including cirrhosis hepatocellular carcinoma (HCC). In Italy, ~2% of subjects are infected with...
This study aimed to evaluate prevalence of prescription and adherence selective serotonin reuptake inhibitors (SSRIs) serotonin-norepinephrine (SNRIs) whether these classes drugs affects overall medication in older persons.In a cross-sectional analysis administrative data comprehensive all prescribed reimbursed by the Italian national health care system, new prescriptions SSRIs SNRIs persons aged 65 years or were analyzed (n = 380,400 2011; 395,806 2012; 409,741 2013, from total sample...
Objective: To investigate the criteria for prescribing a combination pill hypertensive patients, and whether improves medication adherence. Materials methods: This was retrospective cohort study, performed in three Italian local health units. We selected all adult subjects who received at least one prescription of antihypertensive drugs between September 1, 2011 December 31, (the enrollment period). The date first claim defined as index date. For each patient, we documented drug treatments...