- Medical Imaging Techniques and Applications
- Digital Radiography and Breast Imaging
- Radiation Detection and Scintillator Technologies
- Advanced X-ray and CT Imaging
- Nuclear Physics and Applications
- Advanced Radiotherapy Techniques
- Particle Detector Development and Performance
- Nuclear reactor physics and engineering
- Advanced Semiconductor Detectors and Materials
- Radiation Dose and Imaging
- Radiation Therapy and Dosimetry
- Advanced X-ray Imaging Techniques
- AI in cancer detection
- Radioactive contamination and transfer
- Nuclear physics research studies
- Radiomics and Machine Learning in Medical Imaging
- CCD and CMOS Imaging Sensors
- Radioactive element chemistry and processing
- Atomic and Subatomic Physics Research
- Photoacoustic and Ultrasonic Imaging
- Advances in Oncology and Radiotherapy
- Astronomical and nuclear sciences
- Thermography and Photoacoustic Techniques
- Breast Cancer Treatment Studies
- Vestibular and auditory disorders
University of Naples Federico II
2016-2025
Istituto Nazionale di Fisica Nucleare
2006-2025
Istituto Nazionale di Fisica Nucleare, Sezione di Napoli
2015-2024
Ospedale San Giuseppe
2022
University of Pavia
2020
University of Ferrara
2019
Istituto Nazionale di Fisica Nucleare, Sezione di Ferrara
2019
Assistance Publique – Hôpitaux de Paris
2019
Université Paris Cité
2019
Université Toulouse III - Paul Sabatier
2018
The aim of the SYRMA-CT collaboration is to set-up first clinical trial phase-contrast breast CT with synchrotron radiation (SR). In order combine high image quality and low delivered dose a number innovative elements are merged: CdTe single photon counting detector, state-of-the-art reconstruction phase retrieval algorithms. To facilitate an accurate exam optimization, Monte Carlo model was developed for calculation using GEANT4. this study, isotropic spatial resolution (120 μm)3 scans...
We investigated the dose-response of external beam therapy 3 (EBT3) films for proton and carbon ion clinical beams, in comparison with conventional radiotherapy beams; we also measured film response along energy deposition-curve water.We performed measurements at three hadrontherapy centres by delivering monoenergetic pencil beams (protons: 63-230 MeV; ions: 115-400 MeV/u), 0.4-20 Gy dose to water, plateau depth-dose curve.We irradiated MV-photon electron beams.We placed EBT3 water whole...
Breast physical phantoms are a basic tool for the assessment and verification of performance standards in daily clinical practice x-ray breast imaging modalities. They also invaluable testing evaluation new modalities to be potentially established, e.g. computed tomography, dual-energy CT phase-contrast mammography tomography. Nowadays, there is lack or only limited number available this purpose.
The International Consultative Committee for Telephone and Telegraph (CCITT) program of work that addresses global international intelligent network (IN) standards a framework the standardized evolution IN are described. Bell Communication Research's (Bellcore's) work, referred to as Advanced Intelligent Network (AIN), is also discussed in relation CCITT Recommendations. In addition, activities European Telecommunications Standards Institute (ETSI) Technology (TTC) Japan described.< <ETX...
Summary Histamine (H) is stored in man the cardiovascular as well other systems, from where it can be released under exposure to immunologic and nonimmunologic stimuli. To understand better hemodynamic changes produced by endogenous H release, we infused for 3.5–7 min at rate of 0.4 μg/kg/min i.v. four patients with normal left ventricular (LV) function undergoing diagnostic cardiac catheterization. We observed a significant fall systolic, diastolic, mean aortic pressure, systemic vascular...
Breast computed tomography (BCT) is an emerging application of X-ray in radiological practice. A few clinical prototypes are under evaluation hospitals and new systems development aiming at improving spatial contrast resolution reducing delivered dose. At the same time, synchrotron-radiation phase-contrast mammography has been demonstrated to offer substantial advantages when compared with conventional mammography. Elettra, Italian synchrotron radiation facility, a program BCT based on...
To present a dataset of computational digital breast phantoms derived from high-resolution three-dimensional (3D) clinical images for the use in virtual trials two-dimensional (2D) and 3D x-ray imaging.Uncompressed investigations dedicated CT (BCT) were 150 acquired via BCT scanner at UC Davis (California, USA). Each image voxel was classified one out four main materials presented field view: fibroglandular tissue, adipose skin air. For classification, semi-automatic software developed. The...
Towards new and improved techniques in liquid biopsy for the diagnosis of diseases, this study reports experimental evidence a rapid reliable method based on terahertz (THz) time-domain spectroscopic ellipsometry (TDSE) early kidney-related using detection uric acid (UA) content urine. Employing custom-built THz-TDSE system, we analyzed absorption dispersion response synthetic urine samples with varying concentrations UA. The technique provides prompt indication UA presence concentration,...
We present preliminary tests of hybrid pixel detectors consisting the Medipix2 readout chip bump-bonded to a 1-mm-thick CdTe detector. This room temperature imaging system for single photon counting has been developed within European Collaboration various applications with X-rays and gamma rays, including dental radiography, mammography, synchrotron radiation, nuclear medicine, radiation monitoring in facilities. The + detector features 256 /spl times/ square pixels, pitch 55 mu/m, sensitive...
The purpose of this work is to provide an evaluation the mean glandular dose (MGD) for breast computed tomography (CT) with synchrotron radiation in axial scanning configuration a partial or total organ volume irradiation, vivo program CT ongoing at ELETTRA facility (Trieste, Italy). A Geant4 Monte Carlo code was implemented, simulating photon irradiation from source energetic range 8 50 keV 1 intervals, evaluate MGD. validated literature data, terms mammographic normalized coefficients...
This paper presents the test results of second prototype SAMPA, ASIC designed for upgrade read-out front end electronics ALICE Time Projection Chamber (TPC) and Muon (MCH). SAMPA is made in a 130 nm CMOS technology with 1.25 V nominal voltage supply provides 32 channels, selectable input polarity, three possible combinations shaping time sensitivity. Each channel consists Charge Sensitive Amplifier, semi-Gaussian shaper 10-bit ADC; Digital Signal Processor digital filtering compression...
We investigated the influence of model assumptions in GEANT4 Monte Carlo (MC) simulations for calculation monoenergetic and polyenergetic normalized glandular dose coefficients (DgN) mammography, focussing on effect skin thickness composition, role compression paddles bremsstrahlung processes. showed that selecting a 4 mm instead 1.45 produced DgN values with deviations from 9% to 32% x-ray spectra routinely adopted mammography. Consideration radiation had weak DgN. Simulations (in range...