- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Systemic Sclerosis and Related Diseases
- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Cardiovascular Disease and Adiposity
- Cardiac Imaging and Diagnostics
- Cardiovascular Effects of Exercise
- Lipoproteins and Cardiovascular Health
- Heart Failure Treatment and Management
- Cancer, Lipids, and Metabolism
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Syncope and Autonomic Disorders
- Medical Imaging and Pathology Studies
- ECG Monitoring and Analysis
University of Palermo
2023
Instituto di Biofisica
2023
National Research Council
2023
CTO Andrea Alesini
2020-2021
Ospedale degli Infermi
2021
Presidio Ospedaliero
2020
Azienda Ospedaliera G.Rummo
2020
Ospedale Garibaldi
2019
Azienda Ospedaliero Universitaria Maggiore della Carita
2016-2018
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2016-2018
Abstract Aims Recently, the cardiovascular outcomes for people using anticoagulation strategies (COMPASS) trial demonstrated that dual therapy reduced compared with aspirin alone in patients stable atherosclerotic disease. Methods and results We sought to assess proportion of eligible COMPASS compare epidemiology outcome these those without inclusion or any exclusion criteria a contemporary, nationwide cohort coronary artery Among 4068 detailed information allowing evaluation eligibility,...
SARS-CoV-2 infection has caused a global pandemic. Many of the medications identified to treat COVID-19 could be connected with QTc prolongation and its consequences.Non-ICU hospitalized patients three centres involved in study from 19th March 1st May were included this retrospective multicentre study. Relevant clinical data digitally collected. The primary outcome was incidence ≥ 500 ms, main secondary outcomes Tisdale score ability predict ventricular arrhythmias sudden deaths.196...
Aims Increased right atrial size is related to adverse prognosis in pulmonary hypertension. The potential incremental value of function assessment still unclear. We tested the relationship between two-dimensional speckle-tracking echocardiography impairment and hemodynamic, functional clinical deterioration patients with Methods prospectively evaluated 36 (27 female, 9 male; mean age 68 ± 13 years) suspected hypertension undergoing heart catheterization 16 matched controls. All underwent...
Dell’Era, Gabriele; Porcellini, Stefano; Boggio, Enrico; Prenna, Eleonora; Gravellone, Miriam; Varalda, Marco; Erbetta, Riccardo; Lio, Veronica; Occhetta, Eraldo; Marino, Paolo Author Information
Cardiac contractility modulation (CCM) is a treatment option for patients suffering symptomatic chronic heart failure (CHF) with reduced left ventricular ejection fraction (LVEF) who are not eligible cardiac resynchronization. Data on mid-term follow-up limited to small observational studies. The aim of this study was assess the impact CCM quality life, symptoms, exercise tolerance and function in CHF moderate-to-severe systolic dysfunction.Patients LVEF <45% NYHA class >II despite optimal...
Up to one-third of patients undergoing cardiac resynchronization therapy (CRT) are nonresponders. Multipoint bicathodic and cathodic-anodal left ventricle (LV) stimulations could overcome this clinical challenge, but their effectiveness remains controversial. Here we evaluate the performance such through both in vivo silico experiments, latter based on computer electromechanical modeling. Seven patients, all candidates for CRT, received a quadripolar LV lead. Four were tested: right...
Introduction: Systemic sclerosis (SSc) is at risk of developing pulmonary vasculopathy (PV) leading to arterial hypertension (PAH), right heart failure and death. Early detection this life-limiting complication may allow timely therapy improve patients’ survival. Nevertheless, standard non-invasive screening tests are not fully adequate identify milder degrees vascular disease catheterization reserved hemodynamic confirmation. An integrating strategy including reliable specific...
Abstract Background Cardiac re-synchronization therapy (CRT) reduces mortality and hospitalization in patients with heart failure, reduced left ventricular ejection fraction (LVEF) bundle branch block (LBBB). However, there is no conclusive evidence on baseline parameters able to discriminate responder vs non-responder patients. Purpose In this study, we tested whether echocardiographic describing LV dyssynchrony efficiency may predict an acute recovery after CRT lead position can modify...
Abstract Background Cardiac resynchronization therapy (CRT) is an established treatment for heart failure with reduced ejection fraction (HFrEF). However, one third of patients are “non responders”. Cathodic-anodal (CA) left ventricle (LV) capture a multisite pacing occurring during CRT using both bipolar and quadripolar LV lead. It allows depolarization to arise simultaneously from the cathode anode bipole located on epicardium, activating larger volume myocardium than cathodal alone, thus...