A5100447221- Online Learning and Analytics
- Laser-Matter Interactions and Applications
- Complex Network Analysis Techniques
- Advanced Electron Microscopy Techniques and Applications
- Intelligent Tutoring Systems and Adaptive Learning
- Topic Modeling
- Bone Tumor Diagnosis and Treatments
- Caching and Content Delivery
- Spectroscopy and Quantum Chemical Studies
- Natural Language Processing Techniques
- Expert finding and Q&A systems
- Advanced Proteomics Techniques and Applications
- Distributed and Parallel Computing Systems
- Frailty in Older Adults
- Advanced Data Storage Technologies
- Scientific Computing and Data Management
- Photochemistry and Electron Transfer Studies
- Wireless Communication Security Techniques
- Nutrition and Health in Aging
- Security in Wireless Sensor Networks
- Teaching and Learning Programming
- Peptidase Inhibition and Analysis
- Online and Blended Learning
- Musculoskeletal synovial abnormalities and treatments
- Machine Learning in Bioinformatics
Peking University
2011-2024
Peking University Sixth Hospital
2023
Third Affiliated Hospital of Sun Yat-sen University
2023
Sun Yat-sen University
2023
King University
2022
Southern University of Science and Technology
2022
Stanford University
2022
Beijing Jishuitan Hospital
2019-2021
Beijing Haidian Hospital
2016
The Jahn–Teller (JT) distortion is one of the fundamental processes in molecules and condensed phase matters. For photoionized organic with high symmetry, JT effect leads to geometric instability certain electron configurations thus has a significant on subsequent isomerization proton migration processes. Utilizing femtosecond pump–probe Coulomb explosion method, we probe dynamics process monovalent cyclopropane cation (C3H6+) caused by reveal relationship between distortion. We found that...
Abstract Protein language models have demonstrated significant potential in the field of protein engineering. However, current primarily operate at residue scale, which limits their ability to provide information atom level. This limitation prevents us from fully exploiting capabilities for applications involving both proteins and small molecules. In this paper, we propose ESM-AA (ESM All-Atom), a novel approach that enables atom-scale residue-scale unified molecular modeling. achieves by...
Massive Open Online Courses (MOOCs) provide an effective learning platform with various high-quality educational materials accessible to learners from all over the world. However, current MOOCs lack personalized guidance and intelligent assessment for individuals. Though a few recent attempts have been made trace students' knowledge states by adapting popular Bayesian Knowledge Tracing (BKT) model, they largely ignored rich structures correlations among components (KCs) within course. This...
Part of the unique cultural heritage China is Chinese couplet. Given a sentence (namely an antecedent clause), people reply with another subsequent clause) equal in length. Moreover, special phenomenon that corresponding characters from same position two clauses match each other by following certain constraints on semantic and/or syntactic relatedness. Automatic couplet generation computer viewed as difficult problem and has not been fully explored. In this paper, we formulate task natural...
BackgroundMolecular subtyping of cancer aimed to predict patient overall survival (OS) and nominate drug targets for treatments is central precision oncology. Owing the rapid development phosphoproteomics, we can now measure thousands phosphoproteins in human tissues. However, limited studies report how analyse complex phosphoproteomic data druggable kinase candidates.FindingsIn this work, reanalysed high-grade serous ovarian (HGSOC) from Clinical Proteomic Tumour Analysis Consortium...
Social Networks Service (SNS), is becoming more and popular a lot of studies have been carried out in this active field. However, traditional analysis methods based on single machines not suitable because the network growing too large. MapReduce, programming paradigm proposed by Google, gives us new approach to solve large-scale social networks problem making use power multi-machines. In paper, we Hadoop - an open source implementation MapReduce conduct series analyses including several...
Serendipity is a beneficial discovery that happens in an unexpected way. It has been found spectacularly valuable various contexts, including scientific discoveries, acquisition of business, and recommender systems. Although never formally proved with large-scale behavioral analysis, it believed by scientists practitioners serendipity important factor positive user experience increased engagement. In this paper, we take the initiative to study ubiquitous occurrence serendipitious information...
Isocitrate dehydrogenase (IDH) mutations have been reported as biomarkers associated with tumorigenesis and prognosis in gliomas. However, genes affected by these are still under investigation. The purpose of this study is to identify new molecular IDH mutation astrocytic tumors, which account for the largest proportion gliomas.NanoString analysis was conducted on 40 tumors. In total, 69 6 fusion were selected screening. Quantitative real-time polymerase chain reaction immunohistochemistry...
Ubiquitous ultrafast isomerization is paramount in photoexcited molecules, which non-adiabatic coupling among multiple electronic states can occur. We use the pump-probe Coulomb explosion imaging method to study of CH3Cl molecules. find that under our strong field scheme proceeds along pathways, are encoded several distinct branches time-resolved kinetic energy release spectra for CH2++HCl+ channel. Apart from isomerized dissociative pathway neutral and cationic excited states, pump laser...
One of the key obstacles in making learning protocols realistic applications is need to supervise them, a costly process that often requires hiring domain experts. We consider framework use world knowledge as indirect supervision. World general-purpose knowledge, which not designed for any specific domain. Then, challenges are how adapt domains and represent it learning. In this article, we provide an example using domain-dependent document clustering. three ways specify by resolving...
Dedifferentiated central chondrosarcoma (DCCS) is a rare cartilage tumor with invasive biological behavior and poor prognosis. To better understand the morphological characteristics of this type its internal mechanism dedifferentiation, we retrospectively analyzed 57 cases DCCS. A total 29 female 28 male patients were included, ranging in age from 20 to 76 years, median 54 years. Fifty-seven DCCS occurred pelvis ( n = 29), femur 17), scapula 4), tibia 2), humerus metatarsals 1), fibula...
Background: Olfactory identification dysfunction (OID) might be an early sign of amnestic mild cognitive impairment (aMCI). However, odor hedonics, the ability to perceive pleasantness, is neglected. Also, neural substrate OID remains unclear. Objective: To explore characteristics and hedonics in aMCI examine potential correlates by analyzing olfactory functional connectivity (FC) patterns MCI. Methods: Forty-five controls 83 patients were examined. The Chinese smell test was used assess...
In a university library, students from different background are connected by co-borrowing behaviors which form knowledge sharing network. This poster presents novel idea to study the users' book-loan behavior patterns (knowledge patterns) social network perspective enable us understand in both macro-level and micro-level analysis.
In this paper, we investigate the security of wireless communication with friendly jamming in heterogeneous Device-to-Device (D2D) and cellular networks eavesdropper. Not alike traditional physical layer strategies which optimize secrecy capacity, propose aimed at reduction compromised region (CSR). Firstly, outage probability multiple jammers is derived, then obtain given. Secondly, two for are proposed to reduce CSR, including one non-coordinated strategy coordinated strategy. Finally,...
Welcome to the latest installment of "EduBits," your quarterly pipeline new and exciting happenings in world ACM Education. In this edition, a preview third Learning @ Scale conference; news from Tianjin, China on recent summit computing education; an update progress CE2016 curricular volume computer engineering.