A5032734160- Nanoparticle-Based Drug Delivery
- Radiation Therapy and Dosimetry
- Characterization and Applications of Magnetic Nanoparticles
- Hepatocellular Carcinoma Treatment and Prognosis
- Terrorism, Counterterrorism, and Political Violence
- Medical Imaging Techniques and Applications
- Engine and Fuel Emissions
- Islamic Studies and Radicalism
- Electrohydrodynamics and Fluid Dynamics
- Peptidase Inhibition and Analysis
- Radiopharmaceutical Chemistry and Applications
- Chemical Synthesis and Analysis
- Radioactive Decay and Measurement Techniques
- Media, Religion, Digital Communication
- Electrospun Nanofibers in Biomedical Applications
- Technical Engine Diagnostics and Monitoring
- Nanoplatforms for cancer theranostics
- Blood properties and coagulation
- Iron oxide chemistry and applications
- Graphene and Nanomaterials Applications
- Mechanical and Thermal Properties Analysis
- Ultrasound and Hyperthermia Applications
- Microfluidic and Bio-sensing Technologies
University of Warsaw
2020-2023
Silesian University of Technology
2015
It has been proven and confirmed in numerous repeated tests, that the use of a combination several therapeutic methods gives much better treatment results than case separate therapies. Particularly promising is ionizing radiation magnetic hyperthermia one drug. To achieve this objective, magnetite nanoparticles have modified their core with α emitter 225Ac, an amount affecting only slightly properties. By 3-phosphonopropionic acid (CEPA) linker were conjugated covalently trastuzumab...
This study was performed to synthesize a radiopharmaceutical designed for multimodal hepatocellular carcinoma (HCC) treatment involving radionuclide therapy and magnetic hyperthermia. To achieve this goal, the superparamagnetic iron oxide (magnetite) nanoparticles (SPIONs) were covered with layer of radioactive gold (198Au) creating core-shell (SPION@Au). The synthesized SPION@Au exhibited properties saturation magnetization 50 emu/g, which is lower than reported uncoated SPIONs (83 emu/g)....
Cancer is one of the most common causes death worldwide, thus new solutions in anticancer therapies are highly sought after. In this work, superparamagnetic iron oxide nanoparticles (SPIONs) conjugated with drugs synthesized and investigated as potential magnetic drug nanocarriers for local delivery mild hyperthermia. We have obtained a hybrid system loaded holmium thoroughly studied it respect to size, morphology, surface modifications properties, interactions model biological membranes,...
Iron oxide nanoparticles are commonly used in many medical applications as they can be easily modified, have a high surface-to-volume ratio, and biocompatible biodegradable. This study was performed to synthesize designed for multimodal HER2-positive cancer treatment involving radionuclide therapy magnetic hyperthermia. The core (Fe3O4) coated with gold-198 layer creating so-called core-shell nanoparticles. These were then further modified bifunctional PEG linker monoclonal antibody achieve...
Iron oxide-based nanoparticles have been modified in their core with holmium(III) an amount affecting only slightly magnetic properties. Nanoparticles were conjugated covalently biomolecule of trastuzumab (Herceptin®), the monoclonal antibody that recognizes cancer cells overexpressing HER2 receptors targeting such to specified tumor tissues. Systematic studies Ho3+-doped bioconjugates carried out as a preliminary step for future replacement 'cold' Ho 166Ho radionuclide, emitting 'soft'...
Superparamagnetic iron oxide nanoparticles (SPIONs) are widely used for biomedical applications their outstanding properties such as facile functionalization and doping with different metals, high surface-to-volume ratio, superparamagnetism, biocompatibility. This study was designed to synthesize investigate multifunctional nanoparticle conjugate act both a magnetic agent, anticancer immunological drug, radiopharmaceutic therapy. The carrier,
The study aimed to synthesize and characterize the magnetic drug carrier modified with terbium (III) ions. addition of extends possibilities their applications for targeted anticancer radiotherapy as well imaging techniques using radioisotopes emitting β+, β-, α, γ radiation. synthesis iron oxide nanoparticles stabilized citrates co-precipitation method (IONP @ CA) was carried out during experimental work. obtained were used a conjugate containing ions guanosine-5'-monophosphate an analog...
Thermal analysis of a DC motor cooling system and description measurement applied to an engine test stand are the main topics paper. The that is being tested comes from electric vehicle Silesian Greenpower project whose aim design build energy efficient bolids in order participate international races Great Britain. During designing process car, minimizing losses maximizing powertrain efficiency aspects taken into consideration. One crucial issues accomplish these goals maintain optimal...