A5088807420- Metal-Catalyzed Oxygenation Mechanisms
- Oxidative Organic Chemistry Reactions
- Natural Antidiabetic Agents Studies
- Catalytic C–H Functionalization Methods
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Pharmacogenetics and Drug Metabolism
- Vanadium and Halogenation Chemistry
- Cardiac electrophysiology and arrhythmias
- Eicosanoids and Hypertension Pharmacology
- Advances in Cucurbitaceae Research
- Porphyrin and Phthalocyanine Chemistry
- Ginger and Zingiberaceae research
- Heart Rate Variability and Autonomic Control
- Phytochemicals and Antioxidant Activities
- Immune Response and Inflammation
- Metal-Organic Frameworks: Synthesis and Applications
- Natural product bioactivities and synthesis
- Phenothiazines and Benzothiazines Synthesis and Activities
- Infectious Diseases and Mycology
- Transgenic Plants and Applications
- Free Radicals and Antioxidants
- Antifungal resistance and susceptibility
- Cardiac Arrhythmias and Treatments
- Cholesterol and Lipid Metabolism
Indian Institute of Science Education and Research Kolkata
2018-2024
Jadavpur University
2022-2024
National Chemical Laboratory
2017
Indian Institute of Technology Bombay
2013
Nitroolefins are usually synthesized using the Henry reaction. Here we report an alternative metal-free decarboxylative nitration protocol for preparation of nitroolefins from α,β-unsaturated carboxylic acids t-butylnitrite (t-BuONO) and TEMPO. α,β-Unsaturated bearing β-aromatic β-heteroaromatic substituents gave (E)-nitroolefins exclusively under mild conditions. A radical based pathway has been proposed this
The use of a peroxidase-mimicking Fe complex has been reported on the basis biuret-modified TAML macrocyclic ligand framework (Fe-bTAML) as catalyst to perform selective oxidation unactivated 3° C-H bonds and activated 2° with low loading (1 mol %) high product yield (excellent mass balance) under near-neutral conditions broad substrate scope (18 substrates which includes arenes, heteroaromatics, polar functional groups). Aliphatic sites was achieved predictable selectivity using steric,...
One approach to mitigate the crisis of plastic waste is "chemical upcycling", in which either converted into products with higher economic value or depolymerized its constituent monomer(s). Toward this goal, several metal-catalyzed postfunctionalizations polymers have been reported, variable success, mostly on account a lack selectivity, use harsh reaction conditions, and environmentally unfriendly solvents. We herein demonstrate selective hydroxylation backbone 3° C–H bonds synthetic...
One approach to mitigate the crisis of plastic waste is “chemical upcycling”, in which converted into products with higher economic value. Towards this goal, several metal-catalyzed post-functionalization polymers have been reported, variable success, mostly on account lack selectivity, use harsh reaction conditions, and environmentally unfriendly solvents. In work, we demonstrate selective hydroxylation backbone 3° C-H bonds polyolefin macromolecules using in-house developed...
Abstract Introduction The Bruguiera cylindrica L. is a mangrove plant that typically found in coastal areas of Asia, including India. It has been known for its medicinal properties, which have utilized generations. For example, Thailand, it used to treat wounds and diarrhoea, while India, effective addressing diabetes, ulcers, other health issues. This particular study sought investigate the potential B. bark extract reducing symptoms diabetes rats. Methods In this study, we examined as an...
Background: Zingiber rubens Roxb., a new species of the Zingiberaceae family, is found profoundly in Northeastern region India. It rhizomatous geophyte and grows primarily seasonally dry tropical biome native to Indo-China regimens. Objective: The aim research root part this plant discover active constituents evaluate molecular mechanism antidiabetic activity Methods: hydroalcoholic extract (HAZR) was evaluated for in-vitro antioxidant assays α-amylase α-glucosidase inhibition assay....
Cytochrome P450, one of nature's oxidative workhorses, catalyzes the oxidation C-H bonds in complex biological settings. Extensive research has been conducted over past five decades to develop a fully functional mimic that activates O2 or H2O2 water oxidize strong bonds. We report first example synthetic iron functionally mimics cytochrome P450 100% using as oxidant. This complex, which methyl group is replaced with phenyl either wing macrocycle, oxidized unactivated small organic molecules...
Breast adenocarcinoma is one of the leading causes death among women regardless development in field diagnosis, treatment and prevention. Synergistic approaches are emerging as a strategy to overcome monotherapy resistance cancer treatment. Evaluation combinatory activity β-carotene (BC) lupeol (LUP) for anti-proliferative by median effect equation combination index. Validation was performed fixed dose against murine mammary namely Ehrlich ascites carcinoma (EAC). Cytotoxicity assay using...
An oxoiron(IV) cation radical is generated upon two-electron oxidation of an iron(III) complex bearing electron-rich methoxy substituted bTAML framework and thoroughly characterized via multiple spectroscopic techniques density functional theory (DFT). Reactivity studies demonstrate faster rates for strong aliphatic sp3 C-H bonds than its corresponding oxoiron(V) valence tautomer.