A5062068011- Essential Oils and Antimicrobial Activity
- Natural Antidiabetic Agents Studies
- Piperaceae Chemical and Biological Studies
- Phytochemistry and Biological Activities
- Medicinal Plants and Neuroprotection
- Computational Drug Discovery Methods
- Ethnobotanical and Medicinal Plants Studies
- Cytokine Signaling Pathways and Interactions
- interferon and immune responses
- Bioactive natural compounds
- Phytochemicals and Antioxidant Activities
- Phytochemicals and Medicinal Plants
- SARS-CoV-2 and COVID-19 Research
- Advances in Cucurbitaceae Research
- Pharmacological Effects of Natural Compounds
- Natural product bioactivities and synthesis
- Ginger and Zingiberaceae research
- Nanoplatforms for cancer theranostics
- Nanoparticles: synthesis and applications
- Pharmacological Effects of Medicinal Plants
- Protein Kinase Regulation and GTPase Signaling
- Ubiquitin and proteasome pathways
- Nephrotoxicity and Medicinal Plants
- Laser-Ablation Synthesis of Nanoparticles
- COVID-19 Clinical Research Studies
Institute of Bio-Resources and Sustainable Development
2017-2025
Government of India
2020-2025
Institute of Biosciences and Bioresources
2022-2024
Ministry of Science and Technology
2023
Weizmann Institute of Science
2014-2018
Candiolo Cancer Institute
2018
Istituti di Ricovero e Cura a Carattere Scientifico
2018
University of Turin
2011-2017
In this experiment, biosynthesized silver nanoparticles were synthesized using aqueous leaf extract of Erythrina suberosa (Roxb.).The biosynthesis nanoparticle was monitored ultraviolet-visible spectroscopy. The effect the phytoconstituents present in E. suberusa, on formation stable analyzed by fourier-transform infrared size, charge and polydispersity nature studied dynamic light scattering morphology determined scanning electron microscopy. result indicates that glycosides, flavonoids...
A variant of type I interferon stimulates expression only those genes required for an antiviral response.
Artemisia vulgaris is an enormously useful aromatic plant known for its insecticidal, antifungal, parasiticidal, and medicinal values. The main aim of this study to investigate phytochemical contents the potential antimicrobial activities essential oil (AVEO) from fresh leaves A. grown in Manipur. AVEO isolated by hydro-distillation were analyzed gas chromatography/mass spectrometry solid-phase microextraction-GC/MS describe their volatile chemical profile. There 47 components identified...
Immunity boosting has emerged as a global strategy to fight the SARS-CoV-2 pandemic situation. In India, AYUSH systems of medicine have been promoted an immune-protection strategy. Andrographis paniculata (Burm. F) Nees (AP) mentioned in Ayurveda widely used for treating sore throat, flu, and upper respiratory tract infections which may provide possible novel therapeutic approaches, exclusively targeting its pathways.The present work uses liquid chromatography-tandem mass spectrometry...
Abstract Type-I interferons (IFNs) play a key role in the immune defences against viral and bacterial infections, cancer immunosurveillance. We have established that clathrin-dependent endocytosis of type-I interferon (IFN-α/β) receptor (IFNAR) is required for JAK/STAT signalling. Here we show internalized IFNAR1 IFNAR2 subunits IFNAR complex are differentially sorted by retromer at early endosome. Binding VPS35 subunit to results recycling plasma membrane, whereas lysosome degradation....
Introduction: Euryale ferox Salisb. popularly called "Foxnut" is a spiny aquatic plant locally named "Thangjing" in Manipur and one of the most highly consumed crops while Eupatorium birmanicum DC. "Langthrei" an endemic ethnomedicinal found Manipur, India. Methods: This study was carried out to examine phytochemical content, evaluate Total Phenolic Content (TPC), Flavonoid (TFC) vitro antioxidant potential (DPPH ABTS assays) seeds, arils E. leaves birmanicum. Results: Phytochemicals such as...
Capsaicin is the primary bioactive constituent in chillies, responsible for its incomparable pungent taste and many health advantages. In current study, 32 samples of three different species Capsicum (Capsicum annuum L., frutescens chinense Jacq.) from various geographical regions Northeast India were evaluated their total capsaicin content by high performance thin layer chromatography (HPTLC). An excellent separation (Rf = 0.268 ± 0.02) was obtained using toluene ethyl acetate as mobile...
ABSTRACT Introduction Black rice ( Oryza sativa L.) has gained prominence as a functional food because of its rich content anthocyanins and polyphenols, offering potential health benefits. However, comprehensive research addressing the diverse anthocyanin compositions in black cultivars remains limited. Objective This study aimed to quantify contents, specifically kuromanin, cyanidin‐3‐glucoside, peonidin‐3‐O‐glucoside, peonidin‐3‐glucoside chloride, cyanidin‐3‐rutinoside 150 varieties...
ABSTRACT Introduction The Zingiberaceae family is well known for its therapeutic characteristics, notably antidiabetic and antioxidant potential, which may be linked to diverse bioactive metabolite composition. Despite widespread usage in traditional medicine, there has been little research on the chemical composition biological activity of plants from Manipur, India. Objective This study aims comprehensively profile metabolites evaluate properties seven species through vitro assays silico...
Ginger constitutes the rhizome part of plant Zingiber officinale from Zingiberaceae family. A large number ginger varieties with high sensorial and functional quality are found in Northeast India. Hence, phytopharmacological screening different is essential that will serve as a guideline applied research to develop high-end products improve economical margins.
Protein phosphorylation tightly regulates specific binding of effector proteins that control many diverse biological functions cells (e. g. signaling, migration and proliferation). p140Cap is an adaptor protein, specifically expressed in brain, testis epithelial cells, undergoes tunes its interactions with other regulatory molecules via post-translation modification. In this work, using mass spectrometry, we found vivo phosphorylated on tyrosine (Y) within the peptide GEGLpYADPYGLLHEGR (from...