Pardeep Kumar Bhardwaj

ORCID: 0000-0002-3681-3391
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Research Areas
  • Genetic and Environmental Crop Studies
  • Agricultural pest management studies
  • Phytoestrogen effects and research
  • Phytochemistry and Biological Activities
  • Plant Stress Responses and Tolerance
  • Plant biochemistry and biosynthesis
  • Plant Pathogens and Fungal Diseases
  • GABA and Rice Research
  • Cholinesterase and Neurodegenerative Diseases
  • Phytochemicals and Antioxidant Activities
  • Essential Oils and Antimicrobial Activity
  • Ginseng Biological Effects and Applications
  • Pharmacological Effects of Natural Compounds
  • Medicinal Plants and Neuroprotection
  • Food Science and Nutritional Studies
  • Computational Drug Discovery Methods
  • Ethnobotanical and Medicinal Plants Studies
  • Photosynthetic Processes and Mechanisms
  • Phytochemicals and Medicinal Plants
  • Nephrotoxicity and Medicinal Plants
  • Drug-Induced Hepatotoxicity and Protection
  • Botanical Research and Chemistry
  • Phytochemical compounds biological activities
  • Piperaceae Chemical and Biological Studies
  • Phytochemistry and biological activity of medicinal plants

National Institute of Technology Meghalaya
2025

Government of India
2019-2025

Institute of Bio-Resources and Sustainable Development
2014-2025

Ministry of Science and Technology
2019-2023

Sikkim University
2016-2019

Government of Sikkim
2019

Lala Lajpat Rai University of Veterinary and Animal Sciences
2018

Institute of Biosciences and Bioresources
2017

Institute of Himalayan Bioresource Technology
2008-2016

Council of Scientific and Industrial Research
2009-2014

Secondary metabolites are reported to interfere with the isolation of RNA particularly recipes that use guanidinium-based salt. Such interference was observed in medicinal plants rheum (Rheum australe) and arnebia (Arnebia euchroma). A rapid less cumbersome system for essential facilitate any study related gene expression.An free guanidinium salt developed successfully isolated from arnebia. The method took about 45 min evaluated on twenty one tissues varied secondary metabolites. A260/280...

10.1186/1756-0500-4-85 article EN cc-by BMC Research Notes 2011-03-28

Capsaicin is the primary bioactive constituent in chillies, responsible for its incomparable pungent taste and many health advantages. In current study, 32 samples of three different species Capsicum (Capsicum annuum L., frutescens chinense Jacq.) from various geographical regions Northeast India were evaluated their total capsaicin content by high performance thin layer chromatography (HPTLC). An excellent separation (Rf = 0.268 ± 0.02) was obtained using toluene ethyl acetate as mobile...

10.1080/14786419.2025.2450220 article EN Natural Product Research 2025-01-09

ABSTRACT Introduction Black rice ( Oryza sativa L.) has gained prominence as a functional food because of its rich content anthocyanins and polyphenols, offering potential health benefits. However, comprehensive research addressing the diverse anthocyanin compositions in black cultivars remains limited. Objective This study aimed to quantify contents, specifically kuromanin, cyanidin‐3‐glucoside, peonidin‐3‐O‐glucoside, peonidin‐3‐glucoside chloride, cyanidin‐3‐rutinoside 150 varieties...

10.1002/pca.3510 article EN Phytochemical Analysis 2025-01-21

ABSTRACT Introduction The Zingiberaceae family is well known for its therapeutic characteristics, notably antidiabetic and antioxidant potential, which may be linked to diverse bioactive metabolite composition. Despite widespread usage in traditional medicine, there has been little research on the chemical composition biological activity of plants from Manipur, India. Objective This study aims comprehensively profile metabolites evaluate properties seven species through vitro assays silico...

10.1002/pca.3517 article EN Phytochemical Analysis 2025-02-24

Abstract Background Geranyl pyrophosphate (GPP) and p -hydroxybenzoate (PHB) are the basic precursors involved in shikonins biosynthesis. GPP is derived from mevalonate (MVA) and/or 2- C -methyl-D-erythritol 4-phosphate (MEP) pathway(s), depending upon metabolite plant system under consideration. PHB, however, synthesized by only phenylpropanoid (PP) pathway. PHB central moieties to yield through synthesis of m -geranyl- (GHB). Enzyme -hydroxybenzoate- -geranyltransferase (PGT) catalyses...

10.1186/1471-2199-11-88 article EN cc-by BMC Molecular Biology 2010-11-21

The medicinal legume Mucuna pruriens (L.) DC. has attracted attention worldwide as a source of the anti-Parkinson's drug L-Dopa. It is also popular green manure cover crop that offers many agronomic benefits including high protein content, nitrogen fixation and soil nutrients. plant currently lacks genomic resources there limited knowledge on gene expression, metabolic pathways, genetics secondary metabolite production. Here, we present transcriptomic for M. pruriens, de novo transcriptome...

10.1186/s12864-017-3780-9 article EN cc-by BMC Genomics 2017-05-25

Ginger constitutes the rhizome part of plant Zingiber officinale from Zingiberaceae family. A large number ginger varieties with high sensorial and functional quality are found in Northeast India. Hence, phytopharmacological screening different is essential that will serve as a guideline applied research to develop high-end products improve economical margins.

10.1002/pca.3201 article EN Phytochemical Analysis 2023-01-03

Aspergillus terreus is one of the most harmful filamentous fungal pathogen humans, animals and plants. Recently, researchers have discovered that A. can cause foliar blight disease in potato (Solanum tuberosum L.). We used light scanning electron microscopy, performed proteomics analysis an attempt to dissect invasion process this important crop. Microscopic study revealed leaf tissue marked by rapid germination phialidic conidia (PC) 4 h after inoculation. By 8 inoculation, primary germ...

10.1186/1756-0500-7-350 article EN cc-by BMC Research Notes 2014-06-10

Superoxide dismutase (SOD) plays a central role in cellular defence against oxidative stress and is of pharmaceutical importance. The SOD from Potentilla atrosanguinea (Pa-SOD) unique enzyme as it possesses free-radical scavenging capability at temperatures ranging between 263 353 K. crystal structure recombinant Pa-SOD has been determined to 2.3 A resolution. active-site residues are well ordered additional water molecules present place bound copper ion. There significant difference the...

10.1107/s0907444908019069 article EN Acta Crystallographica Section D Biological Crystallography 2008-07-16

The present work was conducted to understand the basis of adaptation in Caragana jubata its niche environment at high altitude cold desert Himalaya. Molecular data showed predominance genes encoding chaperones and those involved growth development low temperature (LT), a major cue operative altitude. Importantly, these expressed C. natural habitat. Their homologues Arabidopsis thaliana, Oryza sativa, Glycine max did not exhibit similar trend gene expression LT. Constitutive quick...

10.1038/srep01022 article EN cc-by-nc-nd Scientific Reports 2013-01-03

This study compared eight major ginsenosides (Rg1, Rg2, Rf, Re, Rd, Rc, Rb1 and Rb2) between Panax sokpayensis bipinnatifidus collected from Sikkim Himalaya, India. High-performance liquid chromatographic analysis revealed that all were present in the rhizomes of P. except ginsenoside whereas Rc Rb2 not detected bipinnatifidus.

10.1080/14786419.2017.1343322 article EN Natural Product Research 2017-06-26

Abstract Background Studying plasticity in gene expression natural systems is crucial, for predicting and managing the effects of climate change on plant species. To understand contribution level variations to abiotic stress compensation a Himalaya ( Primula sikkimensis ), we carried out transplant experiment within (Ambient), beyond (Below Ambient Above Ambient) altitudinal range limit We sequenced nine transcriptomes (three each from condition) using Illumina sequencing technology....

10.1186/s12864-019-6354-1 article EN cc-by BMC Genomics 2019-12-01

Plant and animal pathogenic fungus Cochliobolus lunatus cause great economic damages worldwide every year. C. displays an increased temperature dependent-virulence to a wide range of hosts. Nonetheless, this phenomenon is poorly understood due lack insights on the coordinated secretome weaponries produced by under heat-stress conditions putative To understand mechanism better, we dissected interacting with potato (Solanum tuberosum L.) leaf at different regimes.C. melanized colonizing hyphae...

10.1186/1471-2164-15-213 article EN cc-by BMC Genomics 2014-01-01
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