A5032468086- Radiation Therapy and Dosimetry
- Advanced Radiotherapy Techniques
- Glioma Diagnosis and Treatment
- Mass Spectrometry Techniques and Applications
- Brain Tumor Detection and Classification
- Functional Brain Connectivity Studies
- Medical Imaging Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Optical Imaging and Spectroscopy Techniques
- Molecular Sensors and Ion Detection
- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
- Advanced Proteomics Techniques and Applications
- Photoreceptor and optogenetics research
- Radiomics and Machine Learning in Medical Imaging
- Photochromic and Fluorescence Chemistry
- Ion-surface interactions and analysis
- Esophageal Cancer Research and Treatment
- Luminescence and Fluorescent Materials
- Health Systems, Economic Evaluations, Quality of Life
- Boron Compounds in Chemistry
- Ultrasound and Hyperthermia Applications
- Analytical Chemistry and Chromatography
- Colorectal and Anal Carcinomas
- Brain Metastases and Treatment
Aarhus University Hospital
2017-2025
Aarhus University
2013-2022
Purpose: To present results from the trial radiotherapy quality assurance (RTQA) programme of centres involved in randomised phase-III PROton versus photon Therapy for esophageal Cancer – a Trimodality strategy (PROTECT)-trial, investigating clinical effect proton therapy (PT) vs. (XT) patients with oesophageal cancer. Materials and methods: The pre-trial RTQA consists benchmark target organ at risk (OAR) delineations as well treatment planning cases, facility questionnaire beam output...
The strong UV chromophores thymine (Thy) and uracil (Ura) have identical heteroaromatic rings that only differ by one methyl substituent. While their photophysics has been elucidated in detail, the effect on excited states of base protonation single water molecules is less explored. Here we report gas-phase absorption spectra ThyH(+) UraH(+) monohydrated ions demonstrate substituent not responsible for spectral shifts but also influences tautomer distribution, being different bare ions....
The Danish Neuro Oncology Group (DNOG) has established national consensus guidelines for the delineation of organs at risk (OAR) structures based on published literature. This study was conducted to finalise these and evaluate inter-observer variability delineated OAR by expert observers.The DNOG were formed participants from all centres that treat brain tumours with radiotherapy. In a two-day workshop, discussed finalised pilot study. Following this, ten contoured following OARs T1-weighted...
Microsolvation of chromophore ions commonly has large effects on their electronic structure and as a result optical absorption spectra. Here spectroscopy protonated adenine (AdeH+) its complex with one water molecule isolated in vacuo was done using home-built mass spectrometer combination tuneable pulsed laser system. Experiments also included the adenosine 5′-monophosphate nucleotide (AMPH+). In case bare AdeH+ ions, one-photon leads to four dominant fragment corresponding ammonium formed...
To significantly induce backbone dissociation in a prompt process by ultraviolet light, the photon should be absorbed amide.
Light absorption in the visible region by isolated Ru(bipy)3(+) (bipy = 2,2'-bipyridine) monocations, prepared vacuo reduction of dications collisional electron transfer from cesium atoms, was recorded using photodissociation mass spectroscopy and found to be broad similar that acetonitrile-solvated ions (maximum at 520 nm).
Patients with lower-grade gliomas are long-term survivors after radiotherapy and may benefit from the reduced dose to normal tissue achievable proton therapy. Here, we aimed quantify differences in uninvolved brain contralateral hippocampus compare risk of radiation-induced secondary cancer for photon plans glioma patients.Twenty-three patients were included this in-silico planning comparative study had calculated (50.4 Gy(RBE = 1.1), 28 Fx) applying similar constraints target organs at...
Background and purposeRadiotherapy (RT) of rectal cancer is challenged by potentially large inter-fractional anatomy changes. The risk radiation-induced morbidity a particular concern in patients receiving re-irradiation for recurrent disease. We propose an adaptive RT plan selection strategy these report on its clinical feasibility normal tissue sparing potential.Material methodsEight with pelvic recurrence were re-irradiated according to hyper-fractionation protocol (ReRAD-I; 40.8 Gy)...
Prompt dissociation competes with statistical after photoexcitation of the amide chromophore.
Abstract Background Stereotactic radiosurgery (SRS) is preferred to whole brain radiotherapy (WBRT) for the treatment of patients with a limited number metastases, both as primary and after surgery. SRS can be delivered in single fraction (SF) or multiple fractions (MF) depending on tumor size location. The aim this single-center retrospective study was evaluate intracranial control overall survival (OS) who received SF MF metastases. Material Methods All treated metastases at Aarhus...