A5102931904- Advanced Radiotherapy Techniques
- Prostate Cancer Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Lung Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Prostate Cancer Treatment and Research
- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- Advances in Oncology and Radiotherapy
- Lung Cancer Research Studies
- Breast Implant and Reconstruction
- Medical Imaging and Analysis
- Head and Neck Cancer Studies
- Statistical Methods in Clinical Trials
- Medical Imaging Techniques and Applications
- Breast Lesions and Carcinomas
- Antiplatelet Therapy and Cardiovascular Diseases
- Cancer and Skin Lesions
- Lipoproteins and Cardiovascular Health
- Head and Neck Surgical Oncology
- Economic and Financial Impacts of Cancer
- Heart Rate Variability and Autonomic Control
- Management of metastatic bone disease
- Colorectal and Anal Carcinomas
- Patient-Provider Communication in Healthcare
Northern Cancer Institute
2009-2023
Port Macquarie Base Hospital
2016-2017
UNSW Sydney
2017
University of California, Davis
2013
Coffs Harbour City Council
2009
We hypothesised that severe asthmatics taking a statin drug, in addition to inhaled corticosteroids/long-acting β-agonist inhaler therapy, would have better asthma symptom control and improved lung function compared their controls.A retrospective, cross-sectional study of 165 patients with seen from 2001-2008. Hierarchical linear logistic regression models were used for modelling fitting.University California, Davis Medical Center (Sacramento, USA). Academic, single-centre, subspecialty...
Contouring organs at risk (OARs) is a time-intensive task that critical part of radiation therapy. Atlas-based automatic segmentation has shown some success reducing this time burden on practitioners; however, method often requires significant manual editing to reach clinically accurate standard. Deep learning (DL) auto-segmentation recently emerged as promising solution. This study compares the accuracy DL and atlas-based in relation clinical 'gold standard' reference contours.Ninety CT...
We compare the results of modern external-beam radiotherapy (EBRT), using combined androgen deprivation and dose-escalated intensity-modulated with MRI-CT fusion daily image guidance fiducial markers (DE-IG-IMRT), recently published Australian series brachytherapy surgery.Five-year actuarial biochemical disease-free survival (bDFS), metastasis-free (MFS) prostate cancer-specific (PCaSS) were calculated for 675 patients treated DE-IG-IMRT therapy (ADT). Patients had intermediate-risk (IR)...
Dose-escalated (DE) radiotherapy in the setting of localized prostate cancer has been shown to improve biochemical disease-free survival (bDFS) several studies. In same group patients, androgen deprivation therapy (ADT) confer a benefit when combined with doses up 70 Gy; however, there is currently little long-term data on patients who have received high-dose intensity-modulated (IMRT) ADT. We report outcomes large cohort treated combination DE image-guided IMRT (IG-IMRT) and ADT.Patients...
Abstract Introduction The most recent clinical practice guidelines released by C ancer A ustralia draw attention to unanswered questions concerning the health economic considerations associated with hypofractionated radiotherapy. This study aimed quantify and compare healthcare costs at a regional ustralian radiotherapy institute respect conventionally fractionated post‐mastectomy ( f‐ PMRT ) versus H administration. Methods Medical records of 196 patients treated NSW N orth oast I nstitute...
Purpose. Glioblastoma multiforme (GBM) is optimally treated by maximal debulking followed combined chemoradiation. Intensity modulated radiation therapy (IMRT) gaining widespread acceptance in other tumour sites, although evidence to support its use over three-dimensional conformal (3DCRT) the treatment of gliomas currently lacking. We examined survival outcomes for patients with GBM IMRT and Temozolomide. Methods Materials. In all, 31 were 23 these received chemoradiation correlated patient...
Metaplastic breast carcinoma is an uncommon subtype of invasive ductal with a tendency towards poorer clinical outcomes. Following ethical approval, the current study reviewed institutional records ~2,500 women cancer. A total 14 cases metaplastic cancer were for management and treatment The results demonstrated that patients had median follow up 30 months, 5‑year disease‑free survival 57.1% overall 57.1%. majority at least T2 disease all tumours high grade. Additionally, most triple...
For patients receiving radiotherapy for locally advance non-small cell lung cancer (NSCLC), the probability of experiencing severe radiation pneumonitis (RP) appears to rise with an increase in received by lungs. Intensity modulated (IMRT) provides ability reduce planned doses healthy organs at risk (OAR) and can potentially treatment-related side effects. This study reports toxicity outcomes a dosimetric comparison three-dimensional conformal (3DCRT).Thirty curative NSCLC using...
Oropharyngeal squamous cell carcinoma (OPSCC) incidence has increased over the past two decades largely because of an increase in human papilloma virus (HPV)-related OPSCC. We report here outcomes definitive radiation therapy for OPSCC with simultaneous integrated boost intensity-modulated radiotherapy (IMRT) a regional Australian cancer centre.We retrospectively reviewed electronic medical records (EMR) all patients treated IMRT head and neck cancer. included who received curative intent...
Inverse-planned intensity modulated radiation therapy (IP-IMRT) has potential benefits over other techniques for tangential intact breast radiotherapy. Possible include increased homogeneity, faster planning time, less inter-planner variability and lower doses to organs at risk (OAR). We therefore conducted a pilot study of previously treated patients compare the current forward-planned 'field-in-field' technique (FP-IMRT) with an IP-IMRT alternative.The plans 20 were generated from template...
New techniques for adjuvant radiation therapy after breast conservation include prone positioning, hypofractionation and intensity-modulated (IMRT). Long-term evaluations of this combination are lacking, we report our own experience.Patients with invasive cancer followed a minimum 36 months post-IMRT were eligible. Dose used was 40 Gray in 15 fractions over 3 weeks to the whole via forward-planned prone, IMRT. A 10 Gy 5 fraction supine boost offered.Between January 2012 2020, 2199 patients...
Abstract Radiation Oncology Practice Standards have been developed over the last 10 years and were published for use in Australia 2011. Although majority of radiation oncology community supports implementation standards, there has no mechanism uniform assessment or governance. North Coast Cancer Institute's public service is provided across three main centres on north coast NSW . With a strong focus quality management, we embraced opportunity to demonstrate conformity with The Local Health...
Abstract Introduction Stereotactic ablative radiotherapy (SABR) for lung cancer is a modality of treatment that has improved outcomes patients. However, underutilized and fewer than half elderly patients with non‐small cell (NSCLC) receive active treatment. The purpose this study to report on collaboration in implementing an NSCLC SABR (stereotactic body radiation) program safely, efficiently, uniformly across several centers, including regional sites. first aim paper detail the...
e17507 Background: eviQ is an Australian, web-based point-of-care information resource which aims to improve cancer outcomes by supporting evidence-based practice. Over the last decade, has provided access more than 500 treatment protocols in Medical/Radiation Oncology, Haematology and Cancer Genetics. Each chemotherapy protocol a schedule, administering instructions, side effects, key evidence patient information. Protocols are developed consultation with oncology, haematology genetics...
We evaluated single institution toxicity outcomes after post-prostatectomy radiotherapy (PPRT) via image-guided intensity-modulated radiation therapy (IG-IMRT) with implanted fiducial markers following national eviQ guidelines, for which late have not been published.Prospectively collected data were retrospectively reviewed 293 men who underwent 64-66 Gy IG-IMRT to the prostate bed between 2007 and 2015.Median follow-up PPRT was 39 months. Baseline grade ≥2 genitourinary (GU),...