- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Heart Failure Treatment and Management
- Renal Transplantation Outcomes and Treatments
- Viral Infections and Immunology Research
- Cardiovascular Function and Risk Factors
- Cardiac Arrest and Resuscitation
- Organ Transplantation Techniques and Outcomes
- Cardiac pacing and defibrillation studies
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Hemodynamic Monitoring and Therapy
- Advanced MRI Techniques and Applications
- Ultrasound in Clinical Applications
- Pneumocystis jirovecii pneumonia detection and treatment
- Cytomegalovirus and herpesvirus research
- Cardiomyopathy and Myosin Studies
- Geriatric Care and Nursing Homes
- Blood Pressure and Hypertension Studies
- Antifungal resistance and susceptibility
- Organ and Tissue Transplantation Research
- Chronic Disease Management Strategies
- Amyloidosis: Diagnosis, Treatment, Outcomes
The University of Texas at San Antonio
2020-2024
The University of Texas Health Science Center at San Antonio
2020-2024
International Society for Heart and Lung Transplantation
2024
IFC Research (United Kingdom)
2024
Northwestern Memorial Hospital
2016-2023
Northwestern University
2014-2023
Cardiovascular Institute of the South
2013-2021
The University of Texas Health Science Center at Houston
2020-2021
University of Florida Health
2021
Northwestern Medicine
2015-2019
Mechanical circulatory support with a left ventricular assist device (LVAD) is an established treatment for patients advanced heart failure. We compared newer LVAD design (a small intrapericardial centrifugal-flow device) against existing technology commercially available axial-flow in failure who were ineligible transplantation.
Contemporary ventricular assist device therapy results in a high rate of successful heart transplantation but is associated with bleeding, infections, and other complications. Further reductions pump size, centrifugal design, intrapericardial positioning may reduce complications improve outcomes.We studied small, intrapericardially positioned, continuous-flow patients requiring an implanted as bridge to transplantation. The course investigational recipients was compared that...
Endomyocardial biopsy is the standard method of monitoring for rejection in recipients a cardiac transplant. However, this procedure uncomfortable, and there are risks associated with it. Gene-expression profiling peripheral-blood specimens has been shown to correlate results an endomyocardial biopsy.We randomly assigned 602 patients who had undergone transplantation 6 months 5 years previously be monitored use gene-expression or routine biopsies, addition clinical echocardiographic...
Rationale: Potential benefits of mesenchymal stem cell (MSC) therapy in heart failure may be related to paracrine properties and systemic effects, including anti-inflammatory activities. If this hypothesis is valid, intravenous administration MSCs should improve outcomes failure, an entity which excessive chronic inflammation play a pivotal role. Objective: To assess the safety preliminary efficacy intravenously administered ischemia-tolerant (itMSCs) patients with nonischemic...
In October 2018, the U.S. heart allocation system expanded number of priority "status" tiers from 3 to 6 and added cardiogenic shock requirements for some transplant candidates listed with specific types treatments. This study sought determine impact new policy on treatment practices centers. Initial listing data all adult December 1, 2017 April 30, 2019 were collected Scientific Registry Transplant Recipients. The status-qualifying treatments (or exception requests) hemodynamic values at a...
Driveline (DL) infection has been a major source of morbidity and mortality following HeartMate II left ventricular assist device (LVAD) implant, despite significantly lower incidence compared with pulsatile flow devices. The purpose this study was to compare the DL using two different externalization techniques. Between July 1, 2008, October 15, 2011, 125 consecutive patients underwent LVAD implant at single institution. Patients that in 2008-2009 (n = 45) had velour portion externalized...