A5037387251- Memory and Neural Mechanisms
- Prostate Cancer Treatment and Research
- Child and Animal Learning Development
- Olfactory and Sensory Function Studies
- Neural and Behavioral Psychology Studies
- Radiopharmaceutical Chemistry and Applications
- Neuroscience and Neuropharmacology Research
- Bone health and treatments
- Stress Responses and Cortisol
- Neural dynamics and brain function
- Theological Perspectives and Practices
- Fiber-reinforced polymer composites
- Prostate Cancer Diagnosis and Treatment
- American Constitutional Law and Politics
- Neuroendocrine regulation and behavior
- Sleep and Wakefulness Research
- Religion and Society Interactions
- X-ray Diffraction in Crystallography
- Epoxy Resin Curing Processes
- Diamond and Carbon-based Materials Research
- Mechanical Behavior of Composites
- LGBTQ Health, Identity, and Policy
- Graphite, nuclear technology, radiation studies
- Religion, Spirituality, and Psychology
- Mineralogy and Gemology Studies
University of the Basque Country
2013-2025
UPMC Hillman Cancer Center
2017
San Sebastián University
2017
University of Pittsburgh
2004-2016
University of Washington
2011-2012
Baylor College of Medicine
2012
Duke Medical Center
2011
AstraZeneca (Canada)
2011
Institut Gustave Roussy
2011
Johns Hopkins University
2000-2007
Measurements on X-ray photographs of cylindrical specimens different absorption and thickness taken in a camera without eccentricity show that the error apparent unit-cell dimension is proportional to cos2θ/sinθ + cos2θ/θ. The plot against ½(cos2θ/sinθ cos2θ/θ) linear down θ = 30° for all four used. extrapolated values are good agreement, this extrapolation function accordingly recommended case data from well constructed cameras. Other functions also considered, effect various sources...
The variation with temperature of the a and c unti-cell dimensions hexagonal Ceylon graphite has been measured over range 15°-800°c. by X-ray powder method. At 14°·6c., a=2.4562±0.0001 kx. c=6.6943±0.0007 carbon-carbon bond length, C-C=1.4210±0.0001a.
Four experiments with rats examined the effects of a context switch on inhibition that was acquired during feature-negative discrimination. A target conditioned stimulus paired food when it presented alone but occurred without combined feature stimulus. following training did not disrupt to feature. However, responding more difficult inhibit tested in different context. It is suggested both and target's especially sensitive The may (a) by directly suppressing representation (b) activating...
Extinction may alter the representation of a cue (e.g., it becomes less salient). To assess that idea, three groups learned to suppress mouse clicking in video game negative-patterning (X+/Y+/XY-) and positive-patterning (Z+/W+/ZW++) discriminations followed by extinction X Z. The discrimination should depend on configural is dependent Y. Removal excitatory influence further reduce responding XY. In contrast, if alters X, original XY supporting also be changed, affecting inhibitory control,...
Latent inhibition refers to the retardation in learning an association between a target stimulus and outcome when has been pre-exposed absence of consequences. The inhibitory properties latent inhibitors have subject controversy, as standard training—consisting pre-exposure alone—does not provide inhibitor with ability pass summation test, key criterion for demonstrating genuine inhibition. However, previous research animals shown that specific procedure, which (A) is presented compound...
Two experiments with human participants are presented that differentiate renewal from other behavioral effects can produce a response after extinction. Participants played video game and learned to suppress their behavior when sensor stimuli predicted an attack. Contexts (A, B, & C) were provided by fictitious galaxies where the play took place. In Experiment 1, who received conditioning in A, extinction testing A showed some context specificity of during recovery suppression on test. 2...
A procedure is developed to obtain practical numerical results in connection with the m-out-of-n sliding-window detection problem. This effort was motivated by difficulties previous approaches involving approximation, Markov models, and Monte Carlo simulation. Generating-function methods were found be unsatisfactory for window lengths greater than 6 due their complexity. Instead, a model described that then constructively reduced minimum number of state variables. The are derived binary...
4508 Background: In earlier trials, atrasentan, a potent, selective, oral endothelin A receptor antagonist, significantly delays time to disease progression (TTP) in per-protocol group of hormone-refractory prostate cancer (HRPC) patients identified pre–blind break. We report the results from phase 3 trial. Methods: 809 subjects with metastatic HRPC enrolled into 3, randomized, double-blind, placebo-controlled study 10 mg atrasentan were analyzed (401 placebo, 408 atrasentan). Kaplan-Meier...
4563 Background: Atrasentan (Xinlay), a selective endothelin-A receptor antagonist, has been studied in 2 randomized placebo controlled studies of men with metastatic hormone-refractory prostate cancer (HRPC) using time to disease progression as the primary endpoint. A meta-analysis these was performed more precisely define clinical benefit atrasentan 10 mg this patient population. Methods: subject-specific data conducted on intent-to-treat populations both studies. Time (TTP), bone pain...
Three studies used a computer video game preparation to demonstrate latent inhibition in adult humans. In all participants fired torpedoes at target spaceship by clicking the mouse. Conditioned stimuli (CSs) were presented form of coloured "sensors" bottom screen. Conditioning was conducted pairing sensor with an attack from spaceship. Participants learned suppress their rate mouse for attack. Experiment 1 total 10 preexposures CS, prior conditioning, retarded acquisition suppression. 2...
In 2 experiments, participants completed a computer task in which they judged the probability of outcomes occurring (e.g., flowers growing, bug infestation) given cues treatment soil with fictitious garden product). each 2-phase experiment, cue X was associated 1 outcome Phase and 2nd 2. When led to replaced growing), contextual control observed (Experiments 2). Information learned phase less likely be retrieved when tested context different from where training occurred. did not conflict...